[Preventive and therapeutic effects of recombinant IFN-alpha2b nasal spray on SARS-CoV infection in Macaca mulata].
Identifieur interne : 004518 ( Main/Curation ); précédent : 004517; suivant : 004519[Preventive and therapeutic effects of recombinant IFN-alpha2b nasal spray on SARS-CoV infection in Macaca mulata].
Auteurs : Hong Gao [République populaire de Chine] ; Li-Lan Zhang ; Qiang Wei ; Zhao-Jun Duan ; Xin-Ming Tu ; Zhi-Ai Yu ; Wei Deng ; Li-Ping Zhang ; Lin-Lin Bao ; Bin Zhang ; Wei Tong ; Yun-De Hou ; Bing-Lin Zhang ; Lan Huang ; Chuan QinSource :
- Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology [ 1003-9279 ] ; 2005.
Descripteurs français
- KwdFr :
- Animaux, Antiviraux (usage thérapeutique), Attribution aléatoire, Cellules Vero, Femelle, Interféron alpha (usage thérapeutique), Macaca mulatta, Maladies des singes (), Maladies des singes (traitement médicamenteux), Maladies des singes (virologie), Modèles animaux de maladie humaine, Mâle, Poumon (), Poumon (anatomopathologie), Poumon (virologie), Protéines recombinantes, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (), Virus du SRAS (isolement et purification).
- MESH :
- anatomopathologie : Poumon.
- isolement et purification : Virus du SRAS.
- traitement médicamenteux : Maladies des singes, Syndrome respiratoire aigu sévère.
- usage thérapeutique : Antiviraux, Interféron alpha.
- virologie : Maladies des singes, Poumon, Syndrome respiratoire aigu sévère.
- Animaux, Attribution aléatoire, Cellules Vero, Femelle, Macaca mulatta, Maladies des singes, Modèles animaux de maladie humaine, Mâle, Poumon, Protéines recombinantes, Syndrome respiratoire aigu sévère, Virus du SRAS.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (therapeutic use), Chlorocebus aethiops, Disease Models, Animal, Female, Interferon alpha-2, Interferon-alpha (therapeutic use), Lung (drug effects), Lung (pathology), Lung (virology), Macaca mulatta, Male, Monkey Diseases (drug therapy), Monkey Diseases (prevention & control), Monkey Diseases (virology), Random Allocation, Recombinant Proteins, SARS Virus (drug effects), SARS Virus (isolation & purification), Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (prevention & control), Severe Acute Respiratory Syndrome (virology), Vero Cells.
- MESH :
- chemical , therapeutic use : Antiviral Agents, Interferon-alpha.
- drug effects : Lung, SARS Virus.
- drug therapy : Monkey Diseases, Severe Acute Respiratory Syndrome.
- isolation & purification : SARS Virus.
- pathology : Lung.
- prevention & control : Monkey Diseases, Severe Acute Respiratory Syndrome.
- virology : Lung, Monkey Diseases, Severe Acute Respiratory Syndrome.
- Animals, Chlorocebus aethiops, Disease Models, Animal, Female, Interferon alpha-2, Macaca mulatta, Male, Random Allocation, Recombinant Proteins, Vero Cells.
Abstract
To study the preventive and therapeutic effects of recombinant IFN-alpha2b for nasal spray on SARS-CoV infection in Macaca mulata (rhesus monkey).
PubMed: 16261198
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pubmed:16261198Le document en format XML
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<affiliation wicri:level="1"><nlm:affiliation>Institute of Laboratory Animals Science, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China.</nlm:affiliation>
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<term>Disease Models, Animal</term>
<term>Female</term>
<term>Interferon alpha-2</term>
<term>Interferon-alpha (therapeutic use)</term>
<term>Lung (drug effects)</term>
<term>Lung (pathology)</term>
<term>Lung (virology)</term>
<term>Macaca mulatta</term>
<term>Male</term>
<term>Monkey Diseases (drug therapy)</term>
<term>Monkey Diseases (prevention & control)</term>
<term>Monkey Diseases (virology)</term>
<term>Random Allocation</term>
<term>Recombinant Proteins</term>
<term>SARS Virus (drug effects)</term>
<term>SARS Virus (isolation & purification)</term>
<term>Severe Acute Respiratory Syndrome (drug therapy)</term>
<term>Severe Acute Respiratory Syndrome (prevention & control)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
<term>Vero Cells</term>
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<term>Antiviraux (usage thérapeutique)</term>
<term>Attribution aléatoire</term>
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<term>Femelle</term>
<term>Interféron alpha (usage thérapeutique)</term>
<term>Macaca mulatta</term>
<term>Maladies des singes ()</term>
<term>Maladies des singes (traitement médicamenteux)</term>
<term>Maladies des singes (virologie)</term>
<term>Modèles animaux de maladie humaine</term>
<term>Mâle</term>
<term>Poumon ()</term>
<term>Poumon (anatomopathologie)</term>
<term>Poumon (virologie)</term>
<term>Protéines recombinantes</term>
<term>Syndrome respiratoire aigu sévère ()</term>
<term>Syndrome respiratoire aigu sévère (traitement médicamenteux)</term>
<term>Syndrome respiratoire aigu sévère (virologie)</term>
<term>Virus du SRAS ()</term>
<term>Virus du SRAS (isolement et purification)</term>
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<term>Interferon-alpha</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Poumon</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Lung</term>
<term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Monkey Diseases</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>SARS Virus</term>
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<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus du SRAS</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lung</term>
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<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Monkey Diseases</term>
<term>Severe Acute Respiratory Syndrome</term>
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<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Maladies des singes</term>
<term>Syndrome respiratoire aigu sévère</term>
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<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term>
<term>Interféron alpha</term>
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<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Maladies des singes</term>
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<term>Syndrome respiratoire aigu sévère</term>
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<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Lung</term>
<term>Monkey Diseases</term>
<term>Severe Acute Respiratory Syndrome</term>
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<term>Chlorocebus aethiops</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Interferon alpha-2</term>
<term>Macaca mulatta</term>
<term>Male</term>
<term>Random Allocation</term>
<term>Recombinant Proteins</term>
<term>Vero Cells</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Attribution aléatoire</term>
<term>Cellules Vero</term>
<term>Femelle</term>
<term>Macaca mulatta</term>
<term>Maladies des singes</term>
<term>Modèles animaux de maladie humaine</term>
<term>Mâle</term>
<term>Poumon</term>
<term>Protéines recombinantes</term>
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<front><div type="abstract" xml:lang="en">To study the preventive and therapeutic effects of recombinant IFN-alpha2b for nasal spray on SARS-CoV infection in Macaca mulata (rhesus monkey).</div>
</front>
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</record>
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