Establishment, immortalisation and characterisation of pteropid bat cell lines.
Identifieur interne : 002B24 ( Main/Curation ); précédent : 002B23; suivant : 002B25Establishment, immortalisation and characterisation of pteropid bat cell lines.
Auteurs : Gary Crameri [Australie] ; Shawn Todd ; Samantha Grimley ; Jennifer A. Mceachern ; Glenn A. Marsh ; Craig Smith ; Mary Tachedjian ; Carol De Jong ; Elena R. Virtue ; Meng Yu ; Dieter Bulach ; Jun-Ping Liu ; Wojtek P. Michalski ; Deborah Middleton ; Hume E. Field ; Lin-Fa WangSource :
- PloS one [ 1932-6203 ] ; 2009.
Descripteurs français
- KwdFr :
- Animaux, Chiroptera, Clonage moléculaire, Forme de la cellule (), Humains, Immunité innée (), Immunité innée (immunologie), Infections à hénipavirus (virologie), Interférons (génétique), Lignée de cellules transformées (cytologie), Poly I-C (pharmacologie), Techniques de culture cellulaire (), Virus Hendra (), Virus Hendra (physiologie), Virus Nipah (), Virus Nipah (physiologie), Virus simien 40 (génétique).
- MESH :
- cytologie : Lignée de cellules transformées.
- génétique : Interférons, Virus simien 40.
- immunologie : Immunité innée.
- pharmacologie : Poly I-C.
- physiologie : Virus Hendra, Virus Nipah.
- virologie : Infections à hénipavirus.
- Animaux, Chiroptera, Clonage moléculaire, Forme de la cellule, Humains, Immunité innée, Techniques de culture cellulaire, Virus Hendra, Virus Nipah.
English descriptors
- KwdEn :
- Animals, Cell Culture Techniques (methods), Cell Line, Transformed (cytology), Cell Shape (drug effects), Chiroptera, Cloning, Molecular, Hendra Virus (drug effects), Hendra Virus (physiology), Henipavirus Infections (virology), Humans, Immunity, Innate (drug effects), Immunity, Innate (immunology), Interferons (genetics), Nipah Virus (drug effects), Nipah Virus (physiology), Poly I-C (pharmacology), Simian virus 40 (genetics).
- MESH :
- chemical , genetics : Interferons.
- cytology : Cell Line, Transformed.
- drug effects : Cell Shape, Hendra Virus, Immunity, Innate, Nipah Virus.
- genetics : Simian virus 40.
- immunology : Immunity, Innate.
- methods : Cell Culture Techniques.
- chemical , pharmacology : Poly I-C.
- physiology : Hendra Virus, Nipah Virus.
- virology : Henipavirus Infections.
- Animals, Chiroptera, Cloning, Molecular, Humans.
Abstract
Bats are the suspected natural reservoir hosts for a number of new and emerging zoonotic viruses including Nipah virus, Hendra virus, severe acute respiratory syndrome coronavirus and Ebola virus. Since the discovery of SARS-like coronaviruses in Chinese horseshoe bats, attempts to isolate a SL-CoV from bats have failed and attempts to isolate other bat-borne viruses in various mammalian cell lines have been similarly unsuccessful. New stable bat cell lines are needed to help with these investigations and as tools to assist in the study of bat immunology and virus-host interactions.
DOI: 10.1371/journal.pone.0008266
PubMed: 20011515
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pubmed:20011515Le document en format XML
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<series><title level="j">PloS one</title>
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<term>Cell Culture Techniques (methods)</term>
<term>Cell Line, Transformed (cytology)</term>
<term>Cell Shape (drug effects)</term>
<term>Chiroptera</term>
<term>Cloning, Molecular</term>
<term>Hendra Virus (drug effects)</term>
<term>Hendra Virus (physiology)</term>
<term>Henipavirus Infections (virology)</term>
<term>Humans</term>
<term>Immunity, Innate (drug effects)</term>
<term>Immunity, Innate (immunology)</term>
<term>Interferons (genetics)</term>
<term>Nipah Virus (drug effects)</term>
<term>Nipah Virus (physiology)</term>
<term>Poly I-C (pharmacology)</term>
<term>Simian virus 40 (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Chiroptera</term>
<term>Clonage moléculaire</term>
<term>Forme de la cellule ()</term>
<term>Humains</term>
<term>Immunité innée ()</term>
<term>Immunité innée (immunologie)</term>
<term>Infections à hénipavirus (virologie)</term>
<term>Interférons (génétique)</term>
<term>Lignée de cellules transformées (cytologie)</term>
<term>Poly I-C (pharmacologie)</term>
<term>Techniques de culture cellulaire ()</term>
<term>Virus Hendra ()</term>
<term>Virus Hendra (physiologie)</term>
<term>Virus Nipah ()</term>
<term>Virus Nipah (physiologie)</term>
<term>Virus simien 40 (génétique)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Interferons</term>
</keywords>
<keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Lignée de cellules transformées</term>
</keywords>
<keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Cell Line, Transformed</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Cell Shape</term>
<term>Hendra Virus</term>
<term>Immunity, Innate</term>
<term>Nipah Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Simian virus 40</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Interférons</term>
<term>Virus simien 40</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Immunité innée</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Immunity, Innate</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Cell Culture Techniques</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Poly I-C</term>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Poly I-C</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Virus Hendra</term>
<term>Virus Nipah</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Hendra Virus</term>
<term>Nipah Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à hénipavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Henipavirus Infections</term>
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<term>Chiroptera</term>
<term>Cloning, Molecular</term>
<term>Humans</term>
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<term>Chiroptera</term>
<term>Clonage moléculaire</term>
<term>Forme de la cellule</term>
<term>Humains</term>
<term>Immunité innée</term>
<term>Techniques de culture cellulaire</term>
<term>Virus Hendra</term>
<term>Virus Nipah</term>
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<front><div type="abstract" xml:lang="en">Bats are the suspected natural reservoir hosts for a number of new and emerging zoonotic viruses including Nipah virus, Hendra virus, severe acute respiratory syndrome coronavirus and Ebola virus. Since the discovery of SARS-like coronaviruses in Chinese horseshoe bats, attempts to isolate a SL-CoV from bats have failed and attempts to isolate other bat-borne viruses in various mammalian cell lines have been similarly unsuccessful. New stable bat cell lines are needed to help with these investigations and as tools to assist in the study of bat immunology and virus-host interactions.</div>
</front>
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