High HIV testing uptake and linkage to care in a novel program of home-based HIV counseling and testing with facilitated referral in KwaZulu-Natal, South Africa.
Identifieur interne : 001222 ( PubMed/Curation ); précédent : 001221; suivant : 001223High HIV testing uptake and linkage to care in a novel program of home-based HIV counseling and testing with facilitated referral in KwaZulu-Natal, South Africa.
Auteurs : Heidi Van Rooyen [Afrique du Sud] ; Ruanne V. Barnabas ; Jared M. Baeten ; Zipho Phakathi ; Philip Joseph ; Meighan Krows ; Ting Hong ; Pamela M. Murnane ; James Hughes ; Connie CelumSource :
- Journal of acquired immune deficiency syndromes (1999) [ 1944-7884 ] ; 2013.
Descripteurs français
- KwdFr :
- Acceptation des soins par le patient (), Adolescent, Adulte, Adulte d'âge moyen, Agents antiVIH (usage thérapeutique), Assistance (), Assistance (organisation et administration), Charge virale, Connaissances, attitudes et pratiques en santé, Dépistage systématique (organisation et administration), Femelle, Humains, Infections à VIH (sang), Infections à VIH (traitement médicamenteux), Infections à VIH (épidémiologie), Mâle, Numération des lymphocytes CD4, Observance du traitement médicamenteux (), Orientation vers un spécialiste (), Orientation vers un spécialiste (organisation et administration), Population rurale, Projets pilotes, Prévalence, République d'Afrique du Sud (épidémiologie), Services de soins à domicile (), Services de soins à domicile (organisation et administration), Systèmes automatisés lit malade, Sérodiagnostic du SIDA ().
- MESH :
- organisation et administration : Assistance, Dépistage systématique, Orientation vers un spécialiste, Services de soins à domicile.
- sang : Infections à VIH.
- traitement médicamenteux : Infections à VIH.
- usage thérapeutique : Agents antiVIH.
- épidémiologie : Infections à VIH, République d'Afrique du Sud.
- Acceptation des soins par le patient, Adolescent, Adulte, Adulte d'âge moyen, Assistance, Charge virale, Connaissances, attitudes et pratiques en santé, Femelle, Humains, Mâle, Numération des lymphocytes CD4, Observance du traitement médicamenteux, Orientation vers un spécialiste, Population rurale, Projets pilotes, Prévalence, Services de soins à domicile, Systèmes automatisés lit malade, Sérodiagnostic du SIDA.
- Wicri :
- geographic : Afrique du Sud.
English descriptors
- KwdEn :
- AIDS Serodiagnosis (statistics & numerical data), Adolescent, Adult, Anti-HIV Agents (therapeutic use), CD4 Lymphocyte Count, Counseling (organization & administration), Counseling (statistics & numerical data), Female, HIV Infections (blood), HIV Infections (drug therapy), HIV Infections (epidemiology), Health Knowledge, Attitudes, Practice, Home Care Services (organization & administration), Home Care Services (statistics & numerical data), Humans, Male, Mass Screening (organization & administration), Medication Adherence (statistics & numerical data), Middle Aged, Patient Acceptance of Health Care (statistics & numerical data), Pilot Projects, Point-of-Care Systems, Prevalence, Referral and Consultation (organization & administration), Referral and Consultation (statistics & numerical data), Rural Population, South Africa (epidemiology), Viral Load.
- MESH :
- chemical , therapeutic use : Anti-HIV Agents.
- geographic , epidemiology : South Africa.
- blood : HIV Infections.
- drug therapy : HIV Infections.
- epidemiology : HIV Infections.
- organization & administration : Counseling, Home Care Services, Mass Screening, Referral and Consultation.
- statistics & numerical data : AIDS Serodiagnosis, Counseling, Home Care Services, Medication Adherence, Patient Acceptance of Health Care, Referral and Consultation.
- Adolescent, Adult, CD4 Lymphocyte Count, Female, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Pilot Projects, Point-of-Care Systems, Prevalence, Rural Population, Viral Load.
Abstract
For antiretroviral therapy (ART) to have a population-level HIV prevention impact, high levels of HIV testing and effective linkages to HIV care among HIV-infected persons are required.
DOI: 10.1097/QAI.0b013e31829b567d
PubMed: 23714740
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pubmed:23714740Le document en format XML
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<term>Infections à VIH (traitement médicamenteux)</term>
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<front><div type="abstract" xml:lang="en">For antiretroviral therapy (ART) to have a population-level HIV prevention impact, high levels of HIV testing and effective linkages to HIV care among HIV-infected persons are required.</div>
</front>
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<Title>Journal of acquired immune deficiency syndromes (1999)</Title>
<ISOAbbreviation>J. Acquir. Immune Defic. Syndr.</ISOAbbreviation>
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<ArticleTitle>High HIV testing uptake and linkage to care in a novel program of home-based HIV counseling and testing with facilitated referral in KwaZulu-Natal, South Africa.</ArticleTitle>
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<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">For antiretroviral therapy (ART) to have a population-level HIV prevention impact, high levels of HIV testing and effective linkages to HIV care among HIV-infected persons are required.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We piloted home-based counseling and testing (HBCT) with point-of-care CD4 count testing and follow-up visits to facilitate linkage of HIV-infected persons to local HIV clinics and uptake of ART in rural KwaZulu-Natal, South Africa. Lay counselor follow-up visits at months one, three and six evaluated the primary outcome of linkage to care. Plasma viral load was measured at baseline and month six.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">671 adults were tested for HIV (91% coverage) and 201 (30%) were HIV-infected, of which 73 (36%) were new diagnoses. By month three, 90% of HIV-infected persons not on ART at baseline had visited an HIV clinic and 80% of those eligible for ART at baseline by South African guidelines (CD4≤200 cells/μL at the time of the study) had initiated ART. Among HIV-infected participants who were eligible for ART at baseline, mean viral load decreased by 3.23 log10 copies/mL (p<0.001) and the proportion with viral load suppression increased from 20% to 80% between baseline and month six.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In this pilot of HBCT and linkages to care in KwaZulu-Natal, 91% of adults were tested for HIV. Linkage to care was ∼90% both among newly-identified HIV-infected persons as well as known HIVinfected persons who were not engaged in care. Among those eligible for ART, a high proportion initiated ART and achieved viral suppression, indicating high adherence and reduced infectiousness.</AbstractText>
</Abstract>
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<Author ValidYN="Y"><LastName>Baeten</LastName>
<ForeName>Jared M</ForeName>
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<Initials>Z</Initials>
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<Author ValidYN="Y"><LastName>Hong</LastName>
<ForeName>Ting</ForeName>
<Initials>T</Initials>
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<ForeName>Pamela M</ForeName>
<Initials>PM</Initials>
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