Dynamic HIV-1 genetic recombination and genotypic drug resistance among treatment-experienced adults in northern Ghana.
Identifieur interne : 000731 ( PubMed/Curation ); précédent : 000730; suivant : 000732Dynamic HIV-1 genetic recombination and genotypic drug resistance among treatment-experienced adults in northern Ghana.
Auteurs : Nicholas Israel Nii-Trebi [Ghana] ; James Ashun Mensah Brandful [Ghana] ; Shiro Ibe [Japon] ; Wataru Sugiura [Japon] ; Jacob Samson Barnor [Ghana] ; Patrick Owiredu Bampoh [Ghana] ; Shoji Yamaoka [Japon] ; Tetsuro Matano [Japon] ; Kazuhisa Yoshimura [Japon] ; Koichi Ishikawa [Japon] ; William Kwabena Ampofo [Ghana]Source :
- Journal of medical microbiology [ 1473-5644 ] ; 2017.
Abstract
There have been hardly any reports on the human immunodeficiency virus type 1 (HIV-1) drug-resistance profile from northern Ghana since antiretroviral therapy (ART) was introduced over a decade ago. This study investigated prevailing HIV-1 subtypes and examined the occurrence of drug resistance in ART-experienced patients in Tamale, the capital of the Northern Region of Ghana.
DOI: 10.1099/jmm.0.000621
PubMed: 29068286
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000731
Links to Exploration step
pubmed:29068286Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Dynamic HIV-1 genetic recombination and genotypic drug resistance among treatment-experienced adults in northern Ghana.</title>
<author><name sortKey="Nii Trebi, Nicholas Israel" sort="Nii Trebi, Nicholas Israel" uniqKey="Nii Trebi N" first="Nicholas Israel" last="Nii-Trebi">Nicholas Israel Nii-Trebi</name>
<affiliation wicri:level="1"><nlm:affiliation>3Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>3Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brandful, James Ashun Mensah" sort="Brandful, James Ashun Mensah" uniqKey="Brandful J" first="James Ashun Mensah" last="Brandful">James Ashun Mensah Brandful</name>
<affiliation wicri:level="1"><nlm:affiliation>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ibe, Shiro" sort="Ibe, Shiro" uniqKey="Ibe S" first="Shiro" last="Ibe">Shiro Ibe</name>
<affiliation wicri:level="1"><nlm:affiliation>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sugiura, Wataru" sort="Sugiura, Wataru" uniqKey="Sugiura W" first="Wataru" last="Sugiura">Wataru Sugiura</name>
<affiliation wicri:level="1"><nlm:affiliation>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barnor, Jacob Samson" sort="Barnor, Jacob Samson" uniqKey="Barnor J" first="Jacob Samson" last="Barnor">Jacob Samson Barnor</name>
<affiliation wicri:level="1"><nlm:affiliation>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bampoh, Patrick Owiredu" sort="Bampoh, Patrick Owiredu" uniqKey="Bampoh P" first="Patrick Owiredu" last="Bampoh">Patrick Owiredu Bampoh</name>
<affiliation wicri:level="1"><nlm:affiliation>7Department of Medicine, Tamale Teaching Hospital, Ghana Health Service, Tamale, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>7Department of Medicine, Tamale Teaching Hospital, Ghana Health Service, Tamale</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yamaoka, Shoji" sort="Yamaoka, Shoji" uniqKey="Yamaoka S" first="Shoji" last="Yamaoka">Shoji Yamaoka</name>
<affiliation wicri:level="1"><nlm:affiliation>8Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>8Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Matano, Tetsuro" sort="Matano, Tetsuro" uniqKey="Matano T" first="Tetsuro" last="Matano">Tetsuro Matano</name>
<affiliation wicri:level="1"><nlm:affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yoshimura, Kazuhisa" sort="Yoshimura, Kazuhisa" uniqKey="Yoshimura K" first="Kazuhisa" last="Yoshimura">Kazuhisa Yoshimura</name>
<affiliation wicri:level="1"><nlm:affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ishikawa, Koichi" sort="Ishikawa, Koichi" uniqKey="Ishikawa K" first="Koichi" last="Ishikawa">Koichi Ishikawa</name>
<affiliation wicri:level="1"><nlm:affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ampofo, William Kwabena" sort="Ampofo, William Kwabena" uniqKey="Ampofo W" first="William Kwabena" last="Ampofo">William Kwabena Ampofo</name>
<affiliation wicri:level="1"><nlm:affiliation>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:29068286</idno>
<idno type="pmid">29068286</idno>
<idno type="doi">10.1099/jmm.0.000621</idno>
<idno type="wicri:Area/PubMed/Corpus">000731</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000731</idno>
<idno type="wicri:Area/PubMed/Curation">000731</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000731</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Dynamic HIV-1 genetic recombination and genotypic drug resistance among treatment-experienced adults in northern Ghana.</title>
<author><name sortKey="Nii Trebi, Nicholas Israel" sort="Nii Trebi, Nicholas Israel" uniqKey="Nii Trebi N" first="Nicholas Israel" last="Nii-Trebi">Nicholas Israel Nii-Trebi</name>
<affiliation wicri:level="1"><nlm:affiliation>3Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>3Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brandful, James Ashun Mensah" sort="Brandful, James Ashun Mensah" uniqKey="Brandful J" first="James Ashun Mensah" last="Brandful">James Ashun Mensah Brandful</name>
<affiliation wicri:level="1"><nlm:affiliation>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ibe, Shiro" sort="Ibe, Shiro" uniqKey="Ibe S" first="Shiro" last="Ibe">Shiro Ibe</name>
<affiliation wicri:level="1"><nlm:affiliation>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sugiura, Wataru" sort="Sugiura, Wataru" uniqKey="Sugiura W" first="Wataru" last="Sugiura">Wataru Sugiura</name>
<affiliation wicri:level="1"><nlm:affiliation>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barnor, Jacob Samson" sort="Barnor, Jacob Samson" uniqKey="Barnor J" first="Jacob Samson" last="Barnor">Jacob Samson Barnor</name>
<affiliation wicri:level="1"><nlm:affiliation>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bampoh, Patrick Owiredu" sort="Bampoh, Patrick Owiredu" uniqKey="Bampoh P" first="Patrick Owiredu" last="Bampoh">Patrick Owiredu Bampoh</name>
<affiliation wicri:level="1"><nlm:affiliation>7Department of Medicine, Tamale Teaching Hospital, Ghana Health Service, Tamale, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>7Department of Medicine, Tamale Teaching Hospital, Ghana Health Service, Tamale</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yamaoka, Shoji" sort="Yamaoka, Shoji" uniqKey="Yamaoka S" first="Shoji" last="Yamaoka">Shoji Yamaoka</name>
<affiliation wicri:level="1"><nlm:affiliation>8Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>8Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Matano, Tetsuro" sort="Matano, Tetsuro" uniqKey="Matano T" first="Tetsuro" last="Matano">Tetsuro Matano</name>
<affiliation wicri:level="1"><nlm:affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yoshimura, Kazuhisa" sort="Yoshimura, Kazuhisa" uniqKey="Yoshimura K" first="Kazuhisa" last="Yoshimura">Kazuhisa Yoshimura</name>
<affiliation wicri:level="1"><nlm:affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ishikawa, Koichi" sort="Ishikawa, Koichi" uniqKey="Ishikawa K" first="Koichi" last="Ishikawa">Koichi Ishikawa</name>
<affiliation wicri:level="1"><nlm:affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ampofo, William Kwabena" sort="Ampofo, William Kwabena" uniqKey="Ampofo W" first="William Kwabena" last="Ampofo">William Kwabena Ampofo</name>
<affiliation wicri:level="1"><nlm:affiliation>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.</nlm:affiliation>
<country xml:lang="fr">Ghana</country>
<wicri:regionArea>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of medical microbiology</title>
<idno type="eISSN">1473-5644</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">There have been hardly any reports on the human immunodeficiency virus type 1 (HIV-1) drug-resistance profile from northern Ghana since antiretroviral therapy (ART) was introduced over a decade ago. This study investigated prevailing HIV-1 subtypes and examined the occurrence of drug resistance in ART-experienced patients in Tamale, the capital of the Northern Region of Ghana.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">29068286</PMID>
<DateCreated><Year>2017</Year>
<Month>10</Month>
<Day>25</Day>
</DateCreated>
<DateRevised><Year>2017</Year>
<Month>11</Month>
<Day>06</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1473-5644</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>66</Volume>
<Issue>11</Issue>
<PubDate><Year>2017</Year>
<Month>Nov</Month>
</PubDate>
</JournalIssue>
<Title>Journal of medical microbiology</Title>
<ISOAbbreviation>J. Med. Microbiol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Dynamic HIV-1 genetic recombination and genotypic drug resistance among treatment-experienced adults in northern Ghana.</ArticleTitle>
<Pagination><MedlinePgn>1663-1672</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1099/jmm.0.000621</ELocationID>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">There have been hardly any reports on the human immunodeficiency virus type 1 (HIV-1) drug-resistance profile from northern Ghana since antiretroviral therapy (ART) was introduced over a decade ago. This study investigated prevailing HIV-1 subtypes and examined the occurrence of drug resistance in ART-experienced patients in Tamale, the capital of the Northern Region of Ghana.</AbstractText>
<AbstractText Label="METHODOLOGY" NlmCategory="METHODS">A cross-sectional study was carried out on HIV-infected adult patients receiving first-line ART. HIV viral load (VL) and CD4(+) T-cell counts were measured. The pol gene sequences were analysed for genotypic resistance by an in-house HIV-1 drug-resistance test; the prevailing HIV-1 subtypes were analysed in detail.Results/Key findings. A total of 33 subjects were studied. Participants comprised 11 males (33.3 %) and 22 (66.7 %) females, with a median age of 34.5 years [interquartile range (IQR) 30.0-40.3]. The median duration on ART was 12 months (IQR 8.0-24). Of the 24 subjects successfully genotyped, 10 (41.7 %) viruses possessed at least one mutation conferring resistance to nucleoside or non-nucleoside reverse-transcriptase inhibitors (NRTIs/NNRTIs). Two-class drug resistance to NRTI and NNRTI was mostly detected (25 %, 6/24). The most frequent mutations were lamivudine-resistance M184V and efavirenz/nevirapine-resistance K103N. HIV-1 subtype CRF02_AG was predominant (79.2 %). Other HIV-1 subtypes detected were G (8.3 %), A3 (4.2 %) and importantly two (8.3 %) unique HIV-1 recombinant forms with CRF02_AG/A3 mosaic.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">HIV-1 shows high genetic diversity and on-going viral genetic recombination in the study region. Nearly 42 % of the patients studied harboured a drug-resistant virus. The study underscores the need for continued surveillance of HIV-1 subtype diversity; and of drug-resistance patterns to guide selection of second-line regimens in northern Ghana.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nii-Trebi</LastName>
<ForeName>Nicholas Israel</ForeName>
<Initials>NI</Initials>
<AffiliationInfo><Affiliation>3Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, Ghana.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>2Center for AIDS Research, Kumamoto University, Kumamoto, Japan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Brandful</LastName>
<ForeName>James Ashun Mensah</ForeName>
<Initials>JAM</Initials>
<AffiliationInfo><Affiliation>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ibe</LastName>
<ForeName>Shiro</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sugiura</LastName>
<ForeName>Wataru</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>5Department of Infection and Immunology, Clinical Research Center, National Hospital Organization, Nagoya Medical Center, Nagoya, Japan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>6Department of AIDS Research, Nagoya University Graduate School of Medicine, Nagoya, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Barnor</LastName>
<ForeName>Jacob Samson</ForeName>
<Initials>JS</Initials>
<AffiliationInfo><Affiliation>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bampoh</LastName>
<ForeName>Patrick Owiredu</ForeName>
<Initials>PO</Initials>
<AffiliationInfo><Affiliation>7Department of Medicine, Tamale Teaching Hospital, Ghana Health Service, Tamale, Ghana.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yamaoka</LastName>
<ForeName>Shoji</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>8Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Matano</LastName>
<ForeName>Tetsuro</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>2Center for AIDS Research, Kumamoto University, Kumamoto, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yoshimura</LastName>
<ForeName>Kazuhisa</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>2Center for AIDS Research, Kumamoto University, Kumamoto, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ishikawa</LastName>
<ForeName>Koichi</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>1AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ampofo</LastName>
<ForeName>William Kwabena</ForeName>
<Initials>WK</Initials>
<AffiliationInfo><Affiliation>4Department of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2017</Year>
<Month>10</Month>
<Day>25</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>J Med Microbiol</MedlineTA>
<NlmUniqueID>0224131</NlmUniqueID>
<ISSNLinking>0022-2615</ISSNLinking>
</MedlineJournalInfo>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Antiretroviral therapy</Keyword>
<Keyword MajorTopicYN="N">genotypic resistance</Keyword>
<Keyword MajorTopicYN="N">molecular epidemiology</Keyword>
<Keyword MajorTopicYN="N">recombinant HIV-1</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>10</Month>
<Day>27</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>10</Month>
<Day>27</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2017</Year>
<Month>10</Month>
<Day>26</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">29068286</ArticleId>
<ArticleId IdType="doi">10.1099/jmm.0.000621</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaSubSaharaV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000731 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000731 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= SidaSubSaharaV1 |flux= PubMed |étape= Curation |type= RBID |clé= pubmed:29068286 |texte= Dynamic HIV-1 genetic recombination and genotypic drug resistance among treatment-experienced adults in northern Ghana. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:29068286" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \ | NlmPubMed2Wicri -a SidaSubSaharaV1
![]() | This area was generated with Dilib version V0.6.32. | ![]() |