Screening for Cancer in Persons Living with HIV Infection
Identifieur interne : 001B25 ( Pmc/Corpus ); précédent : 001B24; suivant : 001B26Screening for Cancer in Persons Living with HIV Infection
Auteurs : James J. Goedert ; H. Dean Hosgood ; Robert J. Biggar ; Howard D. Strickler ; Charles S. RabkinSource :
- Trends in cancer [ 2405-8033 ] ; 2016.
Abstract
Survival with human immunodeficiency virus (HIV) infection has greatly improved due to effective antiretroviral therapy (ART). As infectious complications have declined, malignancy now accounts for over one-third of deaths among people living with HIV (PLWH). Based on practices in the general population, cancer screening of PLWH can decrease both morbidity and mortality. In this article, we review and consider directed approaches for colorectal, breast, cervical and lung cancer screening. Furthermore, routine physical examinations may detect lymphomas and skin, anal and oral cancers. Comprehensive cancer prevention in PLWH should also include ART adherence, vaccination against oncogenic viruses, treatment of hepatitis viruses and smoking cessation. Cancer screening for PLWH warrants further research on safety and efficacy as well as targeted efforts to increase adherence.
Url:
DOI: 10.1016/j.trecan.2016.06.007
PubMed: 27891533
PubMed Central: 5120729
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PMC:5120729Le document en format XML
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<author><name sortKey="Goedert, James J" sort="Goedert, James J" uniqKey="Goedert J" first="James J." last="Goedert">James J. Goedert</name>
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<author><name sortKey="Hosgood, H Dean" sort="Hosgood, H Dean" uniqKey="Hosgood H" first="H. Dean" last="Hosgood">H. Dean Hosgood</name>
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<author><name sortKey="Strickler, Howard D" sort="Strickler, Howard D" uniqKey="Strickler H" first="Howard D." last="Strickler">Howard D. Strickler</name>
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<author><name sortKey="Biggar, Robert J" sort="Biggar, Robert J" uniqKey="Biggar R" first="Robert J." last="Biggar">Robert J. Biggar</name>
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<front><div type="abstract" xml:lang="en"><p id="P1">Survival with human immunodeficiency virus (HIV) infection has greatly improved due to effective antiretroviral therapy (ART). As infectious complications have declined, malignancy now accounts for over one-third of deaths among people living with HIV (PLWH). Based on practices in the general population, cancer screening of PLWH can decrease both morbidity and mortality. In this article, we review and consider directed approaches for colorectal, breast, cervical and lung cancer screening. Furthermore, routine physical examinations may detect lymphomas and skin, anal and oral cancers. Comprehensive cancer prevention in PLWH should also include ART adherence, vaccination against oncogenic viruses, treatment of hepatitis viruses and smoking cessation. Cancer screening for PLWH warrants further research on safety and efficacy as well as targeted efforts to increase adherence.</p>
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<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101665956</journal-id>
<journal-id journal-id-type="pubmed-jr-id">44235</journal-id>
<journal-id journal-id-type="nlm-ta">Trends Cancer</journal-id>
<journal-id journal-id-type="iso-abbrev">Trends Cancer</journal-id>
<journal-title-group><journal-title>Trends in cancer</journal-title>
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<title-group><article-title>Screening for Cancer in Persons Living with HIV Infection</article-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Goedert</surname>
<given-names>James J.</given-names>
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<degrees>M.D.</degrees>
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<contrib contrib-type="author"><name><surname>Hosgood</surname>
<given-names>H. Dean</given-names>
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<degrees>Ph.D.</degrees>
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<contrib contrib-type="author"><name><surname>Biggar</surname>
<given-names>Robert J.</given-names>
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<contrib contrib-type="author"><name><surname>Strickler</surname>
<given-names>Howard D.</given-names>
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<degrees>M.D.</degrees>
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<contrib contrib-type="author"><name><surname>Rabkin</surname>
<given-names>Charles S.</given-names>
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<degrees>M.D., M.Sc.</degrees>
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<aff id="A1"><label>1</label>
Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland</aff>
<aff id="A2"><label>2</label>
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York</aff>
<aff id="A3"><label>3</label>
Private practice, Bethesda, Maryland</aff>
<author-notes><corresp id="FN1">Correspondence: Dr. Rabkin, 9609 Medical Center Drive MSC 9767, Bethesda MD 20892. <email>rabkinc@mail.nih.gov</email>
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<pub-date pub-type="nihms-submitted"><day>14</day>
<month>11</month>
<year>2016</year>
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<pub-date pub-type="ppub"><month>8</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>01</day>
<month>8</month>
<year>2017</year>
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<volume>2</volume>
<issue>8</issue>
<fpage>416</fpage>
<lpage>428</lpage>
<pmc-comment>elocation-id from pubmed: 10.1016/j.trecan.2016.06.007</pmc-comment>
<self-uri xlink:href="http://www.sciencedirect.com/science/article/pii/S2405803316300681"></self-uri>
<abstract><p id="P1">Survival with human immunodeficiency virus (HIV) infection has greatly improved due to effective antiretroviral therapy (ART). As infectious complications have declined, malignancy now accounts for over one-third of deaths among people living with HIV (PLWH). Based on practices in the general population, cancer screening of PLWH can decrease both morbidity and mortality. In this article, we review and consider directed approaches for colorectal, breast, cervical and lung cancer screening. Furthermore, routine physical examinations may detect lymphomas and skin, anal and oral cancers. Comprehensive cancer prevention in PLWH should also include ART adherence, vaccination against oncogenic viruses, treatment of hepatitis viruses and smoking cessation. Cancer screening for PLWH warrants further research on safety and efficacy as well as targeted efforts to increase adherence.</p>
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