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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antiretroviral Therapy for the Prevention of HIV Transmission: What Will It Take?</title></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24429438</idno><idno type="pmc">3952607</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952607</idno><idno type="RBID">PMC:3952607</idno><idno type="doi">10.1093/cid/ciu018</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001655</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001655</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antiretroviral Therapy for the Prevention of HIV Transmission: What Will It Take?</title></analytic><series><title level="j">Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America</title><idno type="ISSN">1058-4838</idno><idno type="eISSN">1537-6591</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The promise of antiretroviral therapy (ART) for prevention requires attention to every step of the human immunodeficiency virus (HIV) care continuum, from expanding HIV testing to linkage to and retention in care, to prompt initiation of ART for eligible persons, to virologic suppression.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Infect Dis</journal-id><journal-id journal-id-type="iso-abbrev">Clin. Infect. Dis</journal-id><journal-id journal-id-type="publisher-id">cid</journal-id><journal-id journal-id-type="hwp">cid</journal-id><journal-title-group><journal-title>Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America</journal-title></journal-title-group><issn pub-type="ppub">1058-4838</issn><issn pub-type="epub">1537-6591</issn><publisher><publisher-name>Oxford University Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24429438</article-id><article-id pub-id-type="pmc">3952607</article-id><article-id pub-id-type="doi">10.1093/cid/ciu018</article-id><article-id pub-id-type="publisher-id">ciu018</article-id><article-categories><subj-group subj-group-type="heading"><subject>Invited Articles</subject><subj-group subj-group-type="heading"><subject>HIV/AIDS</subject></subj-group></subj-group><series-title>Editor's choice</series-title></article-categories><title-group><article-title>Antiretroviral Therapy for the Prevention of HIV Transmission: What Will It Take?</article-title></title-group><contrib-group><contrib contrib-type="editor"><name><surname>Mayer</surname><given-names>Kenneth H.</given-names></name><role>Section Editor</role></contrib></contrib-group><contrib-group><contrib contrib-type="author"><name><surname>McNairy</surname><given-names>Margaret L.</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="aff" rid="af2">2</xref></contrib><contrib contrib-type="author"><name><surname>El-Sadr</surname><given-names>Wafaa M.</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="aff" rid="af3">3</xref></contrib></contrib-group><aff id="af1"><label>1</label><addr-line>Mailman School of Public Health</addr-line>,<institution>ICAP at Columbia University</institution></aff><aff id="af2"><label>2</label><institution>Weill-Cornell Medical College</institution></aff><aff id="af3"><label>3</label><addr-line>Department of Epidemiology, Mailman School of Public Health</addr-line>,<institution>Columbia University</institution>,<addr-line>New York, New York</addr-line></aff><author-notes><corresp>Correspondence: Margaret McNairy, MD, MSc, ICAP at Columbia University, Mailman School of Public Health, 722 W 168th St, 7th Floor, New York, NY 10032 (<email>mm3780@columbia.edu</email>).</corresp></author-notes><pub-date pub-type="ppub"><day>1</day><month>4</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>14</day><month>1</month><year>2014</year></pub-date><volume>58</volume><issue>7</issue><fpage>1003</fpage><lpage>1011</lpage><history><date date-type="received"><day>2</day><month>5</month><year>2013</year></date><date date-type="accepted"><day>18</day><month>10</month><year>2013</year></date></history><permissions><copyright-statement>© The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: <email>journals.permissions@oup.com</email>.</copyright-statement><copyright-year>2014</copyright-year></permissions><self-uri content-type="pdf" xlink:type="simple" xlink:href="ciu018.pdf"></self-uri><abstract abstract-type="precis"><p>The promise of antiretroviral therapy (ART) for prevention requires attention to every step of the human immunodeficiency virus (HIV) care continuum, from expanding HIV testing to linkage to and retention in care, to prompt initiation of ART for eligible persons, to virologic suppression.</p></abstract><abstract><p>The evidence in support of use of antiretroviral therapy (ART) for prevention of human immunodeficiency virus (HIV) transmission is encouraging and has stimulated optimism for achieving a dramatic change in the trajectory of the HIV epidemic. Yet, there are substantial challenges that, if not addressed, could be the Achilles’ heel for this concept. These challenges require strengthening every step of the HIV care continuum, including expansion of HIV testing to reach all those with HIV infection, effective linkage to and retention in care, timely initiation of ART, and high levels of treatment adherence with viral load suppression. Also important is the identification of individuals with acute HIV infection whose contribution to HIV transmission may be substantial. Implementation research is needed to identify strategies that address these challenges and to determine the efficacy of ART for prevention in key populations as well as to evaluate the effectiveness of combination strategies for HIV prevention at the population level.</p></abstract><kwd-group><kwd>HIV</kwd><kwd>prevention</kwd><kwd>antiretroviral therapy</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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