Prevention of HIV Infection among Injection Drug Users in Resource-Limited Settings
Identifieur interne : 001211 ( Pmc/Corpus ); précédent : 001210; suivant : 001212Prevention of HIV Infection among Injection Drug Users in Resource-Limited Settings
Auteurs : David Vlahov ; Angela M. Robertson ; Steffanie A. StrathdeeSource :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1058-4838 ] ; 2010.
Abstract
Injection drug use contributes to considerable global morbidity and mortality associated with human immunodeficiency virus (HIV) infection and AIDS and other infections due to blood-borne pathogens through the direct sharing of needles, syringes, and other injection equipment. Of ~16 million injection drug users (IDUs) worldwide, an estimated 3 million are HIV infected. The prevalence of HIV infection among IDUs is high in many countries in Asia and eastern Europe and could exacerbate the HIV epidemic in sub- Saharan Africa. This review summarizes important components of a comprehensive program for prevention of HIV infection in IDUs, including unrestricted legal access to sterile syringes through needle exchange programs and enhanced pharmacy services, treatment for opioid dependence (i.e., methadone and buprenorphine treatment), behavioral interventions, and identification and treatment of noninjection drug and alcohol use, which accounts for increased sexual transmission of HIV. Evidence supports the effectiveness of harm-reduction programs over punitive drug-control policies.
Url:
DOI: 10.1086/651482
PubMed: 20397939
PubMed Central: 3114556
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<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9203213</journal-id><journal-id journal-id-type="pubmed-jr-id">1135</journal-id><journal-id journal-id-type="nlm-ta">Clin Infect Dis</journal-id><journal-title-group><journal-title>Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</journal-title></journal-title-group><issn pub-type="ppub">1058-4838</issn><issn pub-type="epub">1537-6591</issn></journal-meta><article-meta><article-id pub-id-type="pmid">20397939</article-id><article-id pub-id-type="pmc">3114556</article-id><article-id pub-id-type="doi">10.1086/651482</article-id><article-id pub-id-type="manuscript">NIHMS296991</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Prevention of HIV Infection among Injection Drug Users in Resource-Limited Settings</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Vlahov</surname><given-names>David</given-names></name><xref rid="A1" ref-type="aff">1</xref><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Robertson</surname><given-names>Angela M.</given-names></name><xref rid="A3" ref-type="aff">3</xref></contrib><contrib contrib-type="author"><name><surname>Strathdee</surname><given-names>Steffanie A.</given-names></name><xref rid="A3" ref-type="aff">3</xref></contrib></contrib-group><aff id="A1"><label>1</label> Center for Urban Epidemiologic Studies, New York Academy of Medicine, New York, New York</aff><aff id="A2"><label>2</label> Joseph L. Mailman School of Public Health, Columbia University, New York, New York</aff><aff id="A3"><label>3</label> Division of Global Public Health, Department of Medicine, University of California, San Diego, La Jolla</aff><author-notes><corresp id="FN1">Reprints or correspondence: Dr David Vlahov, New York Academy of Medicine, 1216 Fifth Ave, New York, NY 10029, (<email>dvlahov@nyam.org</email>)</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>19</day><month>5</month><year>2011</year></pub-date><pub-date pub-type="ppub"><day>15</day><month>5</month><year>2010</year></pub-date><pub-date pub-type="pmc-release"><day>14</day><month>6</month><year>2011</year></pub-date><volume>50</volume><issue>Suppl 3</issue><fpage>S114</fpage><lpage>S121</lpage><abstract><p id="P1">Injection drug use contributes to considerable global morbidity and mortality associated with human immunodeficiency virus (HIV) infection and AIDS and other infections due to blood-borne pathogens through the direct sharing of needles, syringes, and other injection equipment. Of ~16 million injection drug users (IDUs) worldwide, an estimated 3 million are HIV infected. The prevalence of HIV infection among IDUs is high in many countries in Asia and eastern Europe and could exacerbate the HIV epidemic in sub- Saharan Africa. This review summarizes important components of a comprehensive program for prevention of HIV infection in IDUs, including unrestricted legal access to sterile syringes through needle exchange programs and enhanced pharmacy services, treatment for opioid dependence (i.e., methadone and buprenorphine treatment), behavioral interventions, and identification and treatment of noninjection drug and alcohol use, which accounts for increased sexual transmission of HIV. Evidence supports the effectiveness of harm-reduction programs over punitive drug-control policies.</p></abstract><funding-group><award-group><funding-source country="United States">National Institute on Drug Abuse : NIDA</funding-source><award-id>T32 DA023356-04 || DA</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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