Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253.
Identifieur interne : 001D55 ( Ncbi/Merge ); précédent : 001D54; suivant : 001D56Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253.
Auteurs : S. Swindells [États-Unis] ; L. Komarow ; S. Tripathy ; K P Cain ; R R Macgregor ; J M Achkar ; A. Gupta ; V G Veloso ; A. Asmelash ; A E Omoz-Oarhe ; S. Gengiah ; U. Lalloo ; R. Allen ; C. Shiboski ; J. Andersen ; S S Qasba ; D K KatzensteinSource :
- The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease [ 1815-7920 ] ; 2013.
Descripteurs français
- KwdFr :
- Adulte, Afrique subsaharienne (épidémiologie), Algorithmes, Brésil (épidémiologie), Co-infection, Dépistage systématique (), Expectoration (microbiologie), Femelle, Fièvre (microbiologie), Humains, Inde (épidémiologie), Infections à VIH (diagnostic), Infections à VIH (épidémiologie), Microscopie de fluorescence, Mycobacterium tuberculosis (isolement et purification), Mâle, Norme de soins, Numération des lymphocytes CD4, Perte de poids, Protocoles cliniques, Prévalence, Pérou (épidémiologie), Radiographie thoracique, Sudation, Techniques bactériologiques, Toux (microbiologie), Tuberculose pulmonaire (diagnostic), Tuberculose pulmonaire (microbiologie), Tuberculose pulmonaire (épidémiologie), Valeur prédictive des tests, Études prospectives, Études transversales.
- MESH :
- diagnostic : Infections à VIH, Tuberculose pulmonaire.
- isolement et purification : Mycobacterium tuberculosis.
- microbiologie : Expectoration, Fièvre, Toux, Tuberculose pulmonaire.
- épidémiologie : Afrique subsaharienne, Brésil, Inde, Infections à VIH, Pérou, Tuberculose pulmonaire.
- Adulte, Algorithmes, Co-infection, Dépistage systématique, Femelle, Humains, Microscopie de fluorescence, Mâle, Norme de soins, Numération des lymphocytes CD4, Perte de poids, Protocoles cliniques, Prévalence, Radiographie thoracique, Sudation, Techniques bactériologiques, Valeur prédictive des tests, Études prospectives, Études transversales.
- Wicri :
English descriptors
- KwdEn :
- Adult, Africa South of the Sahara (epidemiology), Algorithms, Bacteriological Techniques, Brazil (epidemiology), CD4 Lymphocyte Count, Clinical Protocols, Coinfection, Cough (microbiology), Cross-Sectional Studies, Female, Fever (microbiology), HIV Infections (diagnosis), HIV Infections (epidemiology), Humans, India (epidemiology), Male, Mass Screening (methods), Microscopy, Fluorescence, Mycobacterium tuberculosis (isolation & purification), Peru (epidemiology), Predictive Value of Tests, Prevalence, Prospective Studies, Radiography, Thoracic, Sputum (microbiology), Standard of Care, Sweating, Tuberculosis, Pulmonary (diagnosis), Tuberculosis, Pulmonary (epidemiology), Tuberculosis, Pulmonary (microbiology), Weight Loss.
- MESH :
- geographic , epidemiology : Africa South of the Sahara, Brazil, India, Peru.
- diagnosis : HIV Infections, Tuberculosis, Pulmonary.
- epidemiology : HIV Infections, Tuberculosis, Pulmonary.
- isolation & purification : Mycobacterium tuberculosis.
- methods : Mass Screening.
- microbiology : Cough, Fever, Sputum, Tuberculosis, Pulmonary.
- Adult, Algorithms, Bacteriological Techniques, CD4 Lymphocyte Count, Clinical Protocols, Coinfection, Cross-Sectional Studies, Female, Humans, Male, Microscopy, Fluorescence, Predictive Value of Tests, Prevalence, Prospective Studies, Radiography, Thoracic, Standard of Care, Sweating, Weight Loss.
Abstract
Improved tuberculosis (TB) screening is urgently needed for human immunodeficiency virus (HIV) infected patients.
DOI: 10.5588/ijtld.12.0737
PubMed: 23485388
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001221
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pubmed:23485388Le document en format XML
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<term>Infections à VIH (diagnostic)</term>
<term>Infections à VIH (épidémiologie)</term>
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<term>Mycobacterium tuberculosis (isolement et purification)</term>
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<term>Pérou</term>
<term>Tuberculose pulmonaire</term>
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<term>Algorithms</term>
<term>Bacteriological Techniques</term>
<term>CD4 Lymphocyte Count</term>
<term>Clinical Protocols</term>
<term>Coinfection</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Microscopy, Fluorescence</term>
<term>Predictive Value of Tests</term>
<term>Prevalence</term>
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<term>Weight Loss</term>
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<term>Algorithmes</term>
<term>Co-infection</term>
<term>Dépistage systématique</term>
<term>Femelle</term>
<term>Humains</term>
<term>Microscopie de fluorescence</term>
<term>Mâle</term>
<term>Norme de soins</term>
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<front><div type="abstract" xml:lang="en">Improved tuberculosis (TB) screening is urgently needed for human immunodeficiency virus (HIV) infected patients.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23485388</PMID>
<DateCreated><Year>2013</Year>
<Month>03</Month>
<Day>14</Day>
</DateCreated>
<DateCompleted><Year>2013</Year>
<Month>08</Month>
<Day>30</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>12</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1815-7920</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>17</Volume>
<Issue>4</Issue>
<PubDate><Year>2013</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease</Title>
<ISOAbbreviation>Int. J. Tuberc. Lung Dis.</ISOAbbreviation>
</Journal>
<ArticleTitle>Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253.</ArticleTitle>
<Pagination><MedlinePgn>532-9</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.5588/ijtld.12.0737</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Improved tuberculosis (TB) screening is urgently needed for human immunodeficiency virus (HIV) infected patients.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">An observational, multi-country, cross-sectional study of HIV-infected patients to compare a standardized diagnostic evaluation (SDE) for TB with standard of care (SOC). SOC evaluations included TB symptom review (current cough, fever, night sweats and/or weight loss), sputum Ziehl-Neelsen staining and chest radiography. SDE screening added extended clinical signs and symptoms and fluorescent microscopy (FM). All participants underwent all evaluations. Mycobacterium tuberculosis on sputum culture was the primary outcome.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 801 participants were enrolled from Botswana, Malawi, South Africa, Zimbabwe, India, Peru and Brazil. The median age was 33 years; 37% were male, and median CD4 count was 275 cells/mm(3). Thirty-one participants (4%) had a positive culture on Löwenstein-Jensen media and 54 (8%) on MGIT. All but one positive culture came from sub-Saharan Africa, where the prevalence of TB was 54/445 (12%). SOC screening had 54% sensitivity (95%CI 40-67) and 76% specificity (95%CI 72-80). Positive and negative predictive values were respectively 24% and 92%. No elements of the SDE improved the predictive values of SOC.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Symptom-based screening with smear microscopy was insufficiently sensitive. More sensitive diagnostic testing is required for HIV-infected patients.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Swindells</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198-8106, USA. sswindells@unmc.edu</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Komarow</LastName>
<ForeName>L</ForeName>
<Initials>L</Initials>
</Author>
<Author ValidYN="Y"><LastName>Tripathy</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Cain</LastName>
<ForeName>K P</ForeName>
<Initials>KP</Initials>
</Author>
<Author ValidYN="Y"><LastName>MacGregor</LastName>
<ForeName>R R</ForeName>
<Initials>RR</Initials>
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<ForeName>J M</ForeName>
<Initials>JM</Initials>
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<ForeName>A</ForeName>
<Initials>A</Initials>
</Author>
<Author ValidYN="Y"><LastName>Veloso</LastName>
<ForeName>V G</ForeName>
<Initials>VG</Initials>
</Author>
<Author ValidYN="Y"><LastName>Asmelash</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
</Author>
<Author ValidYN="Y"><LastName>Omoz-Oarhe</LastName>
<ForeName>A E</ForeName>
<Initials>AE</Initials>
</Author>
<Author ValidYN="Y"><LastName>Gengiah</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Lalloo</LastName>
<ForeName>U</ForeName>
<Initials>U</Initials>
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<Author ValidYN="Y"><LastName>Allen</LastName>
<ForeName>R</ForeName>
<Initials>R</Initials>
</Author>
<Author ValidYN="Y"><LastName>Shiboski</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Andersen</LastName>
<ForeName>J</ForeName>
<Initials>J</Initials>
</Author>
<Author ValidYN="Y"><LastName>Qasba</LastName>
<ForeName>S S</ForeName>
<Initials>SS</Initials>
</Author>
<Author ValidYN="Y"><LastName>Katzenstein</LastName>
<ForeName>D K</ForeName>
<Initials>DK</Initials>
</Author>
<Author ValidYN="Y"><CollectiveName>AIDS Clinical Trials Group 5253 Study Team</CollectiveName>
</Author>
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