Brief Report: Recovery of Bone Mineral Density After Discontinuation of Tenofovir-Based HIV Pre-exposure Prophylaxis.
Identifieur interne : 004308 ( Ncbi/Curation ); précédent : 004307; suivant : 004309Brief Report: Recovery of Bone Mineral Density After Discontinuation of Tenofovir-Based HIV Pre-exposure Prophylaxis.
Auteurs : David V. Glidden [États-Unis] ; Kathleen Mulligan ; Vanessa Mcmahan ; Peter L. Anderson ; Juan Guanira ; Suwat Chariyalertsak ; Susan P. Buchbinder ; Linda Gail Bekker ; Mauro Schechter ; Beatriz Grinsztejn ; Robert M. GrantSource :
- Journal of acquired immune deficiency syndromes (1999) [ 1944-7884 ] ; 2017.
Descripteurs français
- KwdFr :
- Absorptiométrie photonique, Adulte, Agents antiVIH (administration et posologie), Agents antiVIH (effets indésirables), Densité osseuse (), Emtricitabine (administration et posologie), Femelle, Homosexualité masculine, Humains, Infections à VIH (), Infections à VIH (traitement médicamenteux), Maladies osseuses (), Mâle, Observance thérapeutique, Prophylaxie pré-exposition, Ténofovir (administration et posologie), Ténofovir (effets indésirables), Études de suivi.
- MESH :
- administration et posologie : Agents antiVIH, Emtricitabine, Ténofovir.
- effets indésirables : Agents antiVIH, Ténofovir.
- traitement médicamenteux : Infections à VIH.
- Absorptiométrie photonique, Adulte, Densité osseuse, Femelle, Homosexualité masculine, Humains, Infections à VIH, Maladies osseuses, Mâle, Observance thérapeutique, Prophylaxie pré-exposition, Études de suivi.
English descriptors
- KwdEn :
- Absorptiometry, Photon, Adult, Anti-HIV Agents (administration & dosage), Anti-HIV Agents (adverse effects), Bone Density (drug effects), Bone Diseases (chemically induced), Bone Diseases (therapy), Emtricitabine (administration & dosage), Female, Follow-Up Studies, HIV Infections (complications), HIV Infections (drug therapy), HIV Infections (prevention & control), Homosexuality, Male, Humans, Male, Patient Compliance, Pre-Exposure Prophylaxis, Tenofovir (administration & dosage), Tenofovir (adverse effects).
- MESH :
- chemical , administration & dosage : Anti-HIV Agents, Emtricitabine, Tenofovir.
- chemical , adverse effects : Anti-HIV Agents, Tenofovir.
- chemically induced : Bone Diseases.
- complications : HIV Infections.
- drug effects : Bone Density.
- drug therapy : HIV Infections.
- prevention & control : HIV Infections.
- therapy : Bone Diseases.
- Absorptiometry, Photon, Adult, Female, Follow-Up Studies, Homosexuality, Male, Humans, Male, Patient Compliance, Pre-Exposure Prophylaxis.
Abstract
Oral tenofovir disoproxil fumarate (TDF) for HIV prevention and treatment is associated with decreases in bone mineral density (BMD). Previous reports suggest that these changes may be reversible after discontinuation of TDF.
DOI: 10.1097/QAI.0000000000001475
PubMed: 28639995
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<affiliation wicri:level="2"><nlm:affiliation>*Departments of Epidemiology and Biostatistics; †Medicine,University of California, San Francisco, San Francisco, CA; ‡Department of Health Services, University of Washington, Seattle, WA; §Department of Pharmaceutical Sciences, University of Colorado, Denver, Aurora, CO; ∥Investigaciones Médicas en Salud, Lima, Peru; ¶Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; #Bridge HIV, San Francisco Department of Public Health, San Francisco, CA; **Department of Medicine, Desmond Tutu HIV Foundation, Cape Town, South Africa; ††Projeto Praça Onze, Hospital Escola São Francisco de Assis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; ‡‡Evandro Chagas National Institute of Infectious Diseases-Fiocruz, Rio de Janeiro, Brazil; and §§Gladstone Institute of Virology and San Francisco AIDS Foundation, San Francisco, CA.</nlm:affiliation>
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<term>Prophylaxie pré-exposition</term>
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<term>Ténofovir (effets indésirables)</term>
<term>Études de suivi</term>
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<term>Homosexualité masculine</term>
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<front><div type="abstract" xml:lang="en">Oral tenofovir disoproxil fumarate (TDF) for HIV prevention and treatment is associated with decreases in bone mineral density (BMD). Previous reports suggest that these changes may be reversible after discontinuation of TDF.</div>
</front>
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