Hepatitis C Virus in North Africa: An Emerging Threat
Identifieur interne : 003996 ( Ncbi/Checkpoint ); précédent : 003995; suivant : 003997Hepatitis C Virus in North Africa: An Emerging Threat
Auteurs : Mohamed A. Daw [Libye] ; Abdallah El-Bouzedi [Libye] ; Mohamed O. Ahmed [Libye] ; Aghnyia A. Dau [Libye] ; Mohamed M. Agnan [Libye]Source :
- The Scientific World Journal [ 2356-6140 ] ; 2016.
Abstract
Hepatitis C virus is a major public health threat associated with serious clinical consequences worldwide. North Africa is a unique region composed of seven countries that vary considerably in the predisposing factors to microbial diseases both historically and at the present time. The dynamics of HCV in the region are not well documented. The data are both limited and controversial in most of the countries in the region. In North Africa, the epidemiology of HCV is disparate and understanding it has been hampered by regional “epidemiological homogeneity” concepts. As the dynamics of HCV vary from country to country, context-specific research is needed. In this review, we assess studies performed in each country in the general populations as well as among blood donors and groups exposed to the HCV infection. The reported prevalence of HCV ranges from 0.6% to 8.4% in the Maghreb countries and is predominated by genotype 1. In the Nile valley region, it ranges from 2.2% to 18.9% and is dominated by genotype 4. In North African countries, HCV seems to be a serious problem that is driven by different vectors even in different geographical locations within the same country. Efforts should be combined at both the national and regional levels to implement efficient preventive and treatment strategies.
Url:
DOI: 10.1155/2016/7370524
PubMed: 27610403
PubMed Central: 5004010
Affiliations:
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Box 82668, Tripoli, Libya</nlm:aff><country xml:lang="fr">Libye</country><wicri:regionArea>Department of Laboratory Medicine, Faculty of Biotechnology, Tripoli University, P.O. Box 82668, Tripoli</wicri:regionArea><wicri:noRegion>Tripoli</wicri:noRegion></affiliation></author><author><name sortKey="Ahmed, Mohamed O" sort="Ahmed, Mohamed O" uniqKey="Ahmed M" first="Mohamed O." last="Ahmed">Mohamed O. Ahmed</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, Tripoli University, P.O. Box 13662, Tripoli, Libya</nlm:aff><country xml:lang="fr">Libye</country><wicri:regionArea>Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, Tripoli University, P.O. Box 13662, Tripoli</wicri:regionArea><wicri:noRegion>Tripoli</wicri:noRegion></affiliation></author><author><name sortKey="Dau, Aghnyia A" sort="Dau, Aghnyia A" uniqKey="Dau A" first="Aghnyia A." last="Dau">Aghnyia A. Dau</name><affiliation wicri:level="1"><nlm:aff id="I4">Department of Surgery, Tripoli Medical Centre, Faculty of Medicine, Tripoli University, P.O. Box 82668, Tripoli, Libya</nlm:aff><country xml:lang="fr">Libye</country><wicri:regionArea>Department of Surgery, Tripoli Medical Centre, Faculty of Medicine, Tripoli University, P.O. Box 82668, Tripoli</wicri:regionArea><wicri:noRegion>Tripoli</wicri:noRegion></affiliation></author><author><name sortKey="Agnan, Mohamed M" sort="Agnan, Mohamed M" uniqKey="Agnan M" first="Mohamed M." last="Agnan">Mohamed M. Agnan</name><affiliation wicri:level="1"><nlm:aff id="I5">Department of Pharmacology, Faculty of Medical Technology, Algabal Algarbi University, P.O. Box 3321, Nalut, Libya</nlm:aff><country xml:lang="fr">Libye</country><wicri:regionArea>Department of Pharmacology, Faculty of Medical Technology, Algabal Algarbi University, P.O. 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Daw</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Medical Microbiology, Faculty of Medicine, Tripoli University, P.O. Box 82668, Tripoli, Libya</nlm:aff><country xml:lang="fr">Libye</country><wicri:regionArea>Department of Medical Microbiology, Faculty of Medicine, Tripoli University, P.O. Box 82668, Tripoli</wicri:regionArea><wicri:noRegion>Tripoli</wicri:noRegion></affiliation></author><author><name sortKey="El Bouzedi, Abdallah" sort="El Bouzedi, Abdallah" uniqKey="El Bouzedi A" first="Abdallah" last="El-Bouzedi">Abdallah El-Bouzedi</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Laboratory Medicine, Faculty of Biotechnology, Tripoli University, P.O. Box 82668, Tripoli, Libya</nlm:aff><country xml:lang="fr">Libye</country><wicri:regionArea>Department of Laboratory Medicine, Faculty of Biotechnology, Tripoli University, P.O. Box 82668, Tripoli</wicri:regionArea><wicri:noRegion>Tripoli</wicri:noRegion></affiliation></author><author><name sortKey="Ahmed, Mohamed O" sort="Ahmed, Mohamed O" uniqKey="Ahmed M" first="Mohamed O." last="Ahmed">Mohamed O. Ahmed</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, Tripoli University, P.O. Box 13662, Tripoli, Libya</nlm:aff><country xml:lang="fr">Libye</country><wicri:regionArea>Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, Tripoli University, P.O. Box 13662, Tripoli</wicri:regionArea><wicri:noRegion>Tripoli</wicri:noRegion></affiliation></author><author><name sortKey="Dau, Aghnyia A" sort="Dau, Aghnyia A" uniqKey="Dau A" first="Aghnyia A." last="Dau">Aghnyia A. Dau</name><affiliation wicri:level="1"><nlm:aff id="I4">Department of Surgery, Tripoli Medical Centre, Faculty of Medicine, Tripoli University, P.O. Box 82668, Tripoli, Libya</nlm:aff><country xml:lang="fr">Libye</country><wicri:regionArea>Department of Surgery, Tripoli Medical Centre, Faculty of Medicine, Tripoli University, P.O. Box 82668, Tripoli</wicri:regionArea><wicri:noRegion>Tripoli</wicri:noRegion></affiliation></author><author><name sortKey="Agnan, Mohamed M" sort="Agnan, Mohamed M" uniqKey="Agnan M" first="Mohamed M." last="Agnan">Mohamed M. Agnan</name><affiliation wicri:level="1"><nlm:aff id="I5">Department of Pharmacology, Faculty of Medical Technology, Algabal Algarbi University, P.O. Box 3321, Nalut, Libya</nlm:aff><country xml:lang="fr">Libye</country><wicri:regionArea>Department of Pharmacology, Faculty of Medical Technology, Algabal Algarbi University, P.O. Box 3321, Nalut</wicri:regionArea><wicri:noRegion>Nalut</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Scientific World Journal</title><idno type="ISSN">2356-6140</idno><idno type="eISSN">1537-744X</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Hepatitis C virus is a major public health threat associated with serious clinical consequences worldwide. North Africa is a unique region composed of seven countries that vary considerably in the predisposing factors to microbial diseases both historically and at the present time. The dynamics of HCV in the region are not well documented. The data are both limited and controversial in most of the countries in the region. In North Africa, the epidemiology of HCV is disparate and understanding it has been hampered by regional “epidemiological homogeneity” concepts. As the dynamics of HCV vary from country to country, context-specific research is needed. In this review, we assess studies performed in each country in the general populations as well as among blood donors and groups exposed to the HCV infection. The reported prevalence of HCV ranges from 0.6% to 8.4% in the Maghreb countries and is predominated by genotype 1. In the Nile valley region, it ranges from 2.2% to 18.9% and is dominated by genotype 4. In North African countries, HCV seems to be a serious problem that is driven by different vectors even in different geographical locations within the same country. 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Drah</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Libye</li></country></list><tree><country name="Libye"><noRegion><name sortKey="Daw, Mohamed A" sort="Daw, Mohamed A" uniqKey="Daw M" first="Mohamed A." last="Daw">Mohamed A. Daw</name></noRegion><name sortKey="Agnan, Mohamed M" sort="Agnan, Mohamed M" uniqKey="Agnan M" first="Mohamed M." last="Agnan">Mohamed M. Agnan</name><name sortKey="Ahmed, Mohamed O" sort="Ahmed, Mohamed O" uniqKey="Ahmed M" first="Mohamed O." last="Ahmed">Mohamed O. Ahmed</name><name sortKey="Dau, Aghnyia A" sort="Dau, Aghnyia A" uniqKey="Dau A" first="Aghnyia A." last="Dau">Aghnyia A. Dau</name><name sortKey="El Bouzedi, Abdallah" sort="El Bouzedi, Abdallah" uniqKey="El Bouzedi A" first="Abdallah" last="El-Bouzedi">Abdallah El-Bouzedi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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