Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study
Identifieur interne : 000B43 ( Main/Exploration ); précédent : 000B42; suivant : 000B44Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study
Auteurs : Hermela Melese ; Molla Mesele Wassie ; Haile Woldie ; Abilo Tadesse [Éthiopie] ; Nebiyu Mesfin [Éthiopie]Source :
- HIV/AIDS (Auckland, N.Z.) [ 1179-1373 ] ; 2017.
Abstract
Anemia is a major public health problem in HIV patients around the world. It has a negative effect on the quality of life of HIV patients and progression of the HIV disease. In the sub-Saharan African setting, including Ethiopia where both HIV infection and under-nutrition are expected to be high, there is a paucity of data on the matter. This study was aimed to reveal the magnitude and factors associated with anemia among adult HIV patients in Debre-Tabor Hospital, northwest Ethiopia.
A hospital-based cross-sectional study was used among adult HIV patients in Debre-Tabor Hospital from April 1 to May 30, 2015. The diagnosis of anemia was made following the 2011 World Health Organization recommendation on hemoglobin cut-off points. Univariable and multivariable logistic regression was carried out to assess factors associated with anemia.
A total of 377 patients’ charts were reviewed. Most of the participants (n=237, 62.9%) were taking antiretroviral treatment (ART). The overall prevalence of anemia was 23% (95% CI: 19.1, 27.6). Being ART-naïve (adjusted odds ratio [AOR]: 3.37; 95% CI: 1.59, 7.14), having treatment history with anti-tuberculosis (TB) drug (AOR: 3.2; 95% CI: 1.19, 8.67), taking zidovudine (ZDV)-containing ART regimen (AOR: 2.14; 95% CI: 1.03, 4.57), and having recent CD4+ T-lymphocytes count of <200 cells/μL (AOR: 2.13; 95% CI: 1.04, 4.36) were associated with occurrence of anemia among adult HIV patients.
Anemia continues to be a major co-morbidity among adult HIV patients in Ethiopia. Adult HIV patients who are taking ZDV-containing ART, with a history of TB treatment, have a low CD4+T-lymphocytes count and are ART-naïve should be carefully screened and treated for anemia.
Url:
DOI: 10.2147/HIV.S121021
PubMed: 28243151
PubMed Central: 5317259
Affiliations:
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type="main">Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study</title><author><name sortKey="Melese, Hermela" sort="Melese, Hermela" uniqKey="Melese H" first="Hermela" last="Melese">Hermela Melese</name><affiliation><nlm:aff id="af1-hiv-9-025">HIV Follow-up Care Clinic, Debre-Tabor Hospital, Debre-Tabor</nlm:aff><wicri:noCountry code="subfield">Debre-Tabor</wicri:noCountry></affiliation></author><author><name sortKey="Wassie, Molla Mesele" sort="Wassie, Molla Mesele" uniqKey="Wassie M" first="Molla Mesele" last="Wassie">Molla Mesele Wassie</name><affiliation><nlm:aff id="af2-hiv-9-025">Department of Human Nutrition, Institute of Public Health</nlm:aff><wicri:noCountry code="subfield">Institute of Public Health</wicri:noCountry></affiliation></author><author><name sortKey="Woldie, Haile" sort="Woldie, Haile" uniqKey="Woldie H" first="Haile" last="Woldie">Haile Woldie</name><affiliation><nlm:aff id="af2-hiv-9-025">Department of Human Nutrition, Institute of Public Health</nlm:aff><wicri:noCountry code="subfield">Institute of Public Health</wicri:noCountry></affiliation></author><author><name sortKey="Tadesse, Abilo" sort="Tadesse, Abilo" uniqKey="Tadesse A" first="Abilo" last="Tadesse">Abilo Tadesse</name><affiliation wicri:level="1"><nlm:aff id="af3-hiv-9-025">Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia</nlm:aff><country xml:lang="fr">Éthiopie</country><wicri:regionArea>Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar</wicri:regionArea><wicri:noRegion>Gondar</wicri:noRegion></affiliation></author><author><name sortKey="Mesfin, Nebiyu" sort="Mesfin, Nebiyu" uniqKey="Mesfin N" first="Nebiyu" last="Mesfin">Nebiyu Mesfin</name><affiliation wicri:level="1"><nlm:aff id="af3-hiv-9-025">Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia</nlm:aff><country xml:lang="fr">Éthiopie</country><wicri:regionArea>Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar</wicri:regionArea><wicri:noRegion>Gondar</wicri:noRegion></affiliation></author></analytic><series><title level="j">HIV/AIDS (Auckland, N.Z.)</title><idno type="eISSN">1179-1373</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>Anemia is a major public health problem in HIV patients around the world. It has a negative effect on the quality of life of HIV patients and progression of the HIV disease. In the sub-Saharan African setting, including Ethiopia where both HIV infection and under-nutrition are expected to be high, there is a paucity of data on the matter. This study was aimed to reveal the magnitude and factors associated with anemia among adult HIV patients in Debre-Tabor Hospital, northwest Ethiopia.</p></sec><sec><title>Methods</title><p>A hospital-based cross-sectional study was used among adult HIV patients in Debre-Tabor Hospital from April 1 to May 30, 2015. The diagnosis of anemia was made following the 2011 World Health Organization recommendation on hemoglobin cut-off points. Univariable and multivariable logistic regression was carried out to assess factors associated with anemia.</p></sec><sec><title>Results</title><p>A total of 377 patients’ charts were reviewed. Most of the participants (n=237, 62.9%) were taking antiretroviral treatment (ART). The overall prevalence of anemia was 23% (95% CI: 19.1, 27.6). Being ART-naïve (adjusted odds ratio [AOR]: 3.37; 95% CI: 1.59, 7.14), having treatment history with anti-tuberculosis (TB) drug (AOR: 3.2; 95% CI: 1.19, 8.67), taking zidovudine (ZDV)-containing ART regimen (AOR: 2.14; 95% CI: 1.03, 4.57), and having recent CD4+ T-lymphocytes count of <200 cells/μL (AOR: 2.13; 95% CI: 1.04, 4.36) were associated with occurrence of anemia among adult HIV patients.</p></sec><sec><title>Conclusion and recommendation</title><p>Anemia continues to be a major co-morbidity among adult HIV patients in Ethiopia. Adult HIV patients who are taking ZDV-containing ART, with a history of TB treatment, have a low CD4+T-lymphocytes count and are ART-naïve should be carefully screened and treated for anemia.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Mclean, E" uniqKey="Mclean E">E McLean</name></author><author><name sortKey="Cogswell, M" uniqKey="Cogswell M">M Cogswell</name></author><author><name sortKey="Egli, I" uniqKey="Egli I">I Egli</name></author><author><name sortKey="Wojdyla, D" uniqKey="Wojdyla D">D Wojdyla</name></author><author><name sortKey="De Benoist, B" uniqKey="De Benoist B">B De Benoist</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pande, A" uniqKey="Pande A">A Pande</name></author><author><name sortKey="Bhattacharyya, M" uniqKey="Bhattacharyya M">M Bhattacharyya</name></author><author><name sortKey="Pain, S" uniqKey="Pain S">S 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A">AE Ezeamama</name></author><author><name sortKey="Loscher, T" uniqKey="Loscher T">T Löscher</name></author><author><name sortKey="Fawzi, W" uniqKey="Fawzi W">W Fawzi</name></author><author><name sortKey="Guwatudde, D" uniqKey="Guwatudde D">D Guwatudde</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Phe, T" uniqKey="Phe T">T Phe</name></author><author><name sortKey="Thai, S" uniqKey="Thai S">S Thai</name></author><author><name sortKey="Veng, C" uniqKey="Veng C">C Veng</name></author><author><name sortKey="Sok, S" uniqKey="Sok S">S Sok</name></author><author><name sortKey="Lynen, L" uniqKey="Lynen L">L Lynen</name></author><author><name sortKey="Van Griensven, J" uniqKey="Van Griensven J">J van Griensven</name></author></analytic></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Éthiopie</li></country></list><tree><noCountry><name sortKey="Melese, Hermela" sort="Melese, Hermela" uniqKey="Melese H" first="Hermela" last="Melese">Hermela Melese</name><name sortKey="Wassie, Molla Mesele" sort="Wassie, Molla Mesele" uniqKey="Wassie M" first="Molla Mesele" last="Wassie">Molla Mesele Wassie</name><name sortKey="Woldie, Haile" sort="Woldie, Haile" uniqKey="Woldie H" first="Haile" last="Woldie">Haile Woldie</name></noCountry><country name="Éthiopie"><noRegion><name sortKey="Tadesse, Abilo" sort="Tadesse, Abilo" uniqKey="Tadesse A" first="Abilo" last="Tadesse">Abilo Tadesse</name></noRegion><name sortKey="Mesfin, Nebiyu" sort="Mesfin, Nebiyu" uniqKey="Mesfin N" first="Nebiyu" last="Mesfin">Nebiyu Mesfin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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