Measuring the Burden of Neglected Tropical Diseases: The Global Burden of Disease Framework
Identifieur interne : 006460 ( Main/Exploration ); précédent : 006459; suivant : 006461Measuring the Burden of Neglected Tropical Diseases: The Global Burden of Disease Framework
Auteurs : Colin D. Mathers [Suisse] ; Majid Ezzati [États-Unis] ; Alan D. Lopez [Australie]Source :
- PLoS Neglected Tropical Diseases [ 1935-2727 ] ; 2007.
Abstract
Reliable, comparable information about the main causes of disease and injury in populations, and how these are changing, is a critical input for debates about priorities in the health sector. Traditional sources of information about the descriptive epidemiology of diseases, injuries, and risk factors are generally incomplete, fragmented, and of uncertain reliability and comparability. The Global Burden of Disease (GBD) study has provided a conceptual and methodological framework to quantify and compare the health of populations using a summary measure of both mortality and disability, the disability-adjusted life year (DALY).
This paper describes key features of the Global Burden of Disease analytic approach, which provides a standardized measurement framework to permit comparisons across diseases and injuries, as well as risk factors, and a systematic approach to the evaluation of data. The paper describes the evolution of the GBD, starting from the first study for the year 1990, summarizes the methodological improvements incorporated into GBD revisions for the years 2000–2004 carried out by the World Health Organization, and examines priorities and issues for the next major GBD study, funded by the Bill & Melinda Gates Foundation, and commencing in 2007.
The paper presents an overview of summary results from the Global Burden of Disease study 2002, with a particular focus on the neglected tropical diseases, and also an overview of the comparative risk assessment for 26 global risk factors. Taken together, trypanosomiasis, Chagas disease, schistosomiasis, leishmaniasis, lymphatic filariasis, onchocerciasis, intestinal nematode infections, Japanese encephalitis, dengue, and leprosy accounted for an estimated 177,000 deaths worldwide in 2002, mostly in sub-Saharan Africa, and about 20 million DALYs, or 1.3% of the global burden of disease and injuries. Further research is currently underway to revise and update these estimates.
Url:
DOI: 10.1371/journal.pntd.0000114
PubMed: 18060077
PubMed Central: 2100367
Affiliations:
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Mathers</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Information, Evidence and Research Cluster, World Health Organization, Geneva, Switzerland</addr-line></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Information, Evidence and Research Cluster, World Health Organization, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Ezzati, Majid" sort="Ezzati, Majid" uniqKey="Ezzati M" first="Majid" last="Ezzati">Majid Ezzati</name><affiliation wicri:level="2"><nlm:aff id="aff2"><addr-line>Harvard School of Public Health and Harvard University Initiative for Global Health, Cambridge, Massachusetts, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard School of Public Health and Harvard University Initiative for Global Health, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Lopez, Alan D" sort="Lopez, Alan D" uniqKey="Lopez A" first="Alan D." last="Lopez">Alan D. Lopez</name><affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>School of Population Health, University of Queensland, Brisbane, Queensland, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Population Health, University of Queensland, Brisbane, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author></analytic><series><title level="j">PLoS Neglected Tropical Diseases</title><idno type="ISSN">1935-2727</idno><idno type="eISSN">1935-2735</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Reliable, comparable information about the main causes of disease and injury in populations, and how these are changing, is a critical input for debates about priorities in the health sector. Traditional sources of information about the descriptive epidemiology of diseases, injuries, and risk factors are generally incomplete, fragmented, and of uncertain reliability and comparability. The Global Burden of Disease (GBD) study has provided a conceptual and methodological framework to quantify and compare the health of populations using a summary measure of both mortality and disability, the disability-adjusted life year (DALY).</p><p>This paper describes key features of the Global Burden of Disease analytic approach, which provides a standardized measurement framework to permit comparisons across diseases and injuries, as well as risk factors, and a systematic approach to the evaluation of data. The paper describes the evolution of the GBD, starting from the first study for the year 1990, summarizes the methodological improvements incorporated into GBD revisions for the years 2000–2004 carried out by the World Health Organization, and examines priorities and issues for the next major GBD study, funded by the Bill & Melinda Gates Foundation, and commencing in 2007.</p><p>The paper presents an overview of summary results from the Global Burden of Disease study 2002, with a particular focus on the neglected tropical diseases, and also an overview of the comparative risk assessment for 26 global risk factors. Taken together, trypanosomiasis, Chagas disease, schistosomiasis, leishmaniasis, lymphatic filariasis, onchocerciasis, intestinal nematode infections, Japanese encephalitis, dengue, and leprosy accounted for an estimated 177,000 deaths worldwide in 2002, mostly in sub-Saharan Africa, and about 20 million DALYs, or 1.3% of the global burden of disease and injuries. 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Vounatsou</name></author><author><name sortKey="Singer, Bh" uniqKey="Singer B">BH Singer</name></author><author><name sortKey="N Goran, Ek" uniqKey="N Goran E">EK N'Goran</name></author><author><name sortKey="Tanner, M" uniqKey="Tanner M">M Tanner</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Australie</li><li>Suisse</li><li>États-Unis</li></country><region><li>Massachusetts</li></region></list><tree><country name="Suisse"><noRegion><name sortKey="Mathers, Colin D" sort="Mathers, Colin D" uniqKey="Mathers C" first="Colin D." last="Mathers">Colin D. Mathers</name></noRegion></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Ezzati, Majid" sort="Ezzati, Majid" uniqKey="Ezzati M" first="Majid" last="Ezzati">Majid Ezzati</name></region></country><country name="Australie"><noRegion><name sortKey="Lopez, Alan D" sort="Lopez, Alan D" uniqKey="Lopez A" first="Alan D." last="Lopez">Alan D. Lopez</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|area= SidaSubSaharaV1
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|texte= Measuring the Burden of Neglected Tropical Diseases: The Global Burden of Disease Framework
}}
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