Acute kidney injury in the tropics
Identifieur interne : 003E74 ( Main/Exploration ); précédent : 003E73; suivant : 003E75Acute kidney injury in the tropics
Auteurs : Ashish Jacob Mathew ; Jacob George [Inde]Source :
- Annals of Saudi Medicine [ 0256-4947 ] ; 2011.
Abstract
Acute kidney injury (AKI) is one of the most challenging problems faced by clinicians in the tropics owing to its fast-changing burden. AKI in the tropics is strikingly different from that in the developed world in terms of etiology and presentation. In addition, there is a stark contrast between well-developed and poor areas in the tropics. The true epidemiological picture of AKI in the tropics is not well understood due to the late presentation of patients to tertiary centers. Infections remain the major culprit in most cases of AKI, with high mortality rates in the tropics. Human immunodeficiency virus–related AKI, related to nephrotoxicity due to antiretroviral therapy, is on the rise. Acute tubular necrosis and thrombotic microangiopathy are the most common mechanisms of AKI. A notable problem in the tropics is the scarcity of resources in health centers to support patients who require critical care due to AKI. This article reviews the unique and contrasting nature of AKI in the tropics and describes its management in each situation.
Url:
DOI: 10.4103/0256-4947.84620
PubMed: 21911980
PubMed Central: 3183677
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Acute kidney injury in the tropics</title><author><name sortKey="Mathew, Ashish Jacob" sort="Mathew, Ashish Jacob" uniqKey="Mathew A" first="Ashish Jacob" last="Mathew">Ashish Jacob Mathew</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="George, Jacob" sort="George, Jacob" uniqKey="George J" first="Jacob" last="George">Jacob George</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Nephrology, Medical College Hospital, Trivandrum, Kerala, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Nephrology, Medical College Hospital, Trivandrum, Kerala</wicri:regionArea><wicri:noRegion>Kerala</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21911980</idno><idno type="pmc">3183677</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183677</idno><idno type="RBID">PMC:3183677</idno><idno type="doi">10.4103/0256-4947.84620</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">002D99</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002D99</idno><idno type="wicri:Area/Pmc/Curation">002D98</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002D98</idno><idno type="wicri:Area/Pmc/Checkpoint">002378</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002378</idno><idno type="wicri:Area/Ncbi/Merge">001443</idno><idno type="wicri:Area/Ncbi/Curation">001443</idno><idno type="wicri:Area/Ncbi/Checkpoint">001443</idno><idno type="wicri:doubleKey">0256-4947:2011:Mathew A:acute:kidney:injury</idno><idno type="wicri:Area/Main/Merge">003F17</idno><idno type="wicri:Area/Main/Curation">003E74</idno><idno type="wicri:Area/Main/Exploration">003E74</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Acute kidney injury in the tropics</title><author><name sortKey="Mathew, Ashish Jacob" sort="Mathew, Ashish Jacob" uniqKey="Mathew A" first="Ashish Jacob" last="Mathew">Ashish Jacob Mathew</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="George, Jacob" sort="George, Jacob" uniqKey="George J" first="Jacob" last="George">Jacob George</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Nephrology, Medical College Hospital, Trivandrum, Kerala, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Nephrology, Medical College Hospital, Trivandrum, Kerala</wicri:regionArea><wicri:noRegion>Kerala</wicri:noRegion></affiliation></author></analytic><series><title level="j">Annals of Saudi Medicine</title><idno type="ISSN">0256-4947</idno><idno type="eISSN">0975-4466</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Acute kidney injury (AKI) is one of the most challenging problems faced by clinicians in the tropics owing to its fast-changing burden. AKI in the tropics is strikingly different from that in the developed world in terms of etiology and presentation. In addition, there is a stark contrast between well-developed and poor areas in the tropics. The true epidemiological picture of AKI in the tropics is not well understood due to the late presentation of patients to tertiary centers. Infections remain the major culprit in most cases of AKI, with high mortality rates in the tropics. Human immunodeficiency virus–related AKI, related to nephrotoxicity due to antiretroviral therapy, is on the rise. Acute tubular necrosis and thrombotic microangiopathy are the most common mechanisms of AKI. A notable problem in the tropics is the scarcity of resources in health centers to support patients who require critical care due to AKI. This article reviews the unique and contrasting nature of AKI in the tropics and describes its management in each situation.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Lameire, N" uniqKey="Lameire N">N Lameire</name></author><author><name sortKey="Van, Bw" uniqKey="Van B">BW Van</name></author><author><name sortKey="Vanholder, R" uniqKey="Vanholder R">R Vanholder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chugh, Ks" uniqKey="Chugh K">KS Chugh</name></author><author><name sortKey="Sitprija, V" uniqKey="Sitprija V">V Sitprija</name></author><author><name sortKey="Jha, V" uniqKey="Jha V">V Jha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burdmann, Ea" uniqKey="Burdmann E">EA Burdmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chugh, Ks" uniqKey="Chugh K">KS Chugh</name></author><author><name sortKey="Sakhuja, 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Murthy</name></author><author><name sortKey="Srivastava, Pk" uniqKey="Srivastava P">PK Srivastava</name></author><author><name sortKey="Tripathi, K" uniqKey="Tripathi K">K Tripathi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Srivastava, Rn" uniqKey="Srivastava R">RN Srivastava</name></author><author><name sortKey="Bagga, A" uniqKey="Bagga A">A Bagga</name></author><author><name sortKey="Moudgil, A" uniqKey="Moudgil A">A Moudgil</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Mathew, Ashish Jacob" sort="Mathew, Ashish Jacob" uniqKey="Mathew A" first="Ashish Jacob" last="Mathew">Ashish Jacob Mathew</name></noCountry><country name="Inde"><noRegion><name sortKey="George, Jacob" sort="George, Jacob" uniqKey="George J" first="Jacob" last="George">Jacob George</name></noRegion></country></tree></affiliations></record>Pour manipuler ce 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