Acute kidney injury in the tropics
Identifieur interne : 002D98 ( Pmc/Curation ); précédent : 002D97; suivant : 002D99Acute kidney injury in the tropics
Auteurs : Ashish Jacob Mathew ; Jacob George [Inde]Source :
- Annals of Saudi Medicine [ 0256-4947 ] ; 2011.
Abstract
Acute kidney injury (AKI) is one of the most challenging problems faced by clinicians in the tropics owing to its fast-changing burden. AKI in the tropics is strikingly different from that in the developed world in terms of etiology and presentation. In addition, there is a stark contrast between well-developed and poor areas in the tropics. The true epidemiological picture of AKI in the tropics is not well understood due to the late presentation of patients to tertiary centers. Infections remain the major culprit in most cases of AKI, with high mortality rates in the tropics. Human immunodeficiency virus–related AKI, related to nephrotoxicity due to antiretroviral therapy, is on the rise. Acute tubular necrosis and thrombotic microangiopathy are the most common mechanisms of AKI. A notable problem in the tropics is the scarcity of resources in health centers to support patients who require critical care due to AKI. This article reviews the unique and contrasting nature of AKI in the tropics and describes its management in each situation.
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DOI: 10.4103/0256-4947.84620
PubMed: 21911980
PubMed Central: 3183677
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Acute kidney injury in the tropics</title><author><name sortKey="Mathew, Ashish Jacob" sort="Mathew, Ashish Jacob" uniqKey="Mathew A" first="Ashish Jacob" last="Mathew">Ashish Jacob Mathew</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="George, Jacob" sort="George, Jacob" uniqKey="George J" first="Jacob" last="George">Jacob George</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Nephrology, Medical College Hospital, Trivandrum, Kerala, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Nephrology, Medical College Hospital, Trivandrum, Kerala</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21911980</idno><idno type="pmc">3183677</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183677</idno><idno type="RBID">PMC:3183677</idno><idno type="doi">10.4103/0256-4947.84620</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">002D99</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002D99</idno><idno type="wicri:Area/Pmc/Curation">002D98</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002D98</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Acute kidney injury in the tropics</title><author><name sortKey="Mathew, Ashish Jacob" sort="Mathew, Ashish Jacob" uniqKey="Mathew A" first="Ashish Jacob" last="Mathew">Ashish Jacob Mathew</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="George, Jacob" sort="George, Jacob" uniqKey="George J" first="Jacob" last="George">Jacob George</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Nephrology, Medical College Hospital, Trivandrum, Kerala, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Nephrology, Medical College Hospital, Trivandrum, Kerala</wicri:regionArea></affiliation></author></analytic><series><title level="j">Annals of Saudi Medicine</title><idno type="ISSN">0256-4947</idno><idno type="eISSN">0975-4466</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Acute kidney injury (AKI) is one of the most challenging problems faced by clinicians in the tropics owing to its fast-changing burden. AKI in the tropics is strikingly different from that in the developed world in terms of etiology and presentation. In addition, there is a stark contrast between well-developed and poor areas in the tropics. The true epidemiological picture of AKI in the tropics is not well understood due to the late presentation of patients to tertiary centers. Infections remain the major culprit in most cases of AKI, with high mortality rates in the tropics. Human immunodeficiency virus–related AKI, related to nephrotoxicity due to antiretroviral therapy, is on the rise. Acute tubular necrosis and thrombotic microangiopathy are the most common mechanisms of AKI. A notable problem in the tropics is the scarcity of resources in health centers to support patients who require critical care due to AKI. This article reviews the unique and contrasting nature of AKI in the tropics and describes its management in each situation.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Lameire, N" uniqKey="Lameire N">N Lameire</name></author><author><name sortKey="Van, Bw" uniqKey="Van B">BW Van</name></author><author><name sortKey="Vanholder, R" uniqKey="Vanholder R">R Vanholder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chugh, Ks" uniqKey="Chugh K">KS Chugh</name></author><author><name sortKey="Sitprija, V" uniqKey="Sitprija V">V Sitprija</name></author><author><name sortKey="Jha, V" uniqKey="Jha V">V Jha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burdmann, Ea" uniqKey="Burdmann E">EA Burdmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chugh, Ks" uniqKey="Chugh K">KS Chugh</name></author><author><name sortKey="Sakhuja, 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Ann Saudi Med</journal-id><journal-id journal-id-type="publisher-id">ASM</journal-id><journal-title-group><journal-title>Annals of Saudi Medicine</journal-title></journal-title-group><issn pub-type="ppub">0256-4947</issn><issn pub-type="epub">0975-4466</issn><publisher><publisher-name>Medknow Publications</publisher-name><publisher-loc>India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">21911980</article-id><article-id pub-id-type="pmc">3183677</article-id><article-id pub-id-type="publisher-id">ASM-31-451</article-id><article-id pub-id-type="doi">10.4103/0256-4947.84620</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Acute kidney injury in the tropics</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Mathew</surname><given-names>Ashish Jacob</given-names></name><xref ref-type="aff" rid="aff1">a</xref></contrib><contrib contrib-type="author"><name><surname>George</surname><given-names>Jacob</given-names></name><xref ref-type="aff" rid="aff2">b</xref><xref ref-type="corresp" rid="cor1"></xref></contrib></contrib-group><aff id="aff1">From the<label>a</label>Department of Internal Medicine, Medical College Hospital, Trivandrum, Kerala, India</aff><aff id="aff2"><label>b</label>Department of Nephrology, Medical College Hospital, Trivandrum, Kerala, India</aff><author-notes><corresp id="cor1">Correspondence: Dr. Jacob George · Department of Nephrology, Medical College Hospital, Trivandrum, Kerala 695 011, India · <email xlink:href="drjacobgeo@rediffmail.com">drjacobgeo@rediffmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><season>Sep-Oct</season><year>2011</year></pub-date><volume>31</volume><issue>5</issue><fpage>451</fpage><lpage>456</lpage><history><date date-type="accepted"><month>8</month><year>2010</year></date></history><permissions><copyright-statement>© Annals of Saudi Medicine</copyright-statement><copyright-year>2011</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>Acute kidney injury (AKI) is one of the most challenging problems faced by clinicians in the tropics owing to its fast-changing burden. AKI in the tropics is strikingly different from that in the developed world in terms of etiology and presentation. In addition, there is a stark contrast between well-developed and poor areas in the tropics. The true epidemiological picture of AKI in the tropics is not well understood due to the late presentation of patients to tertiary centers. Infections remain the major culprit in most cases of AKI, with high mortality rates in the tropics. Human immunodeficiency virus–related AKI, related to nephrotoxicity due to antiretroviral therapy, is on the rise. Acute tubular necrosis and thrombotic microangiopathy are the most common mechanisms of AKI. A notable problem in the tropics is the scarcity of resources in health centers to support patients who require critical care due to AKI. This article reviews the unique and contrasting nature of AKI in the tropics and describes its management in each situation.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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