Le SIDA au Ghana (serveur d'exploration)

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[Isolation of HIV-2 from AIDS patient in Ghana and analysis of sero-reactive patterns of Ghanaian sera].

Identifieur interne : 000307 ( PubMed/Curation ); précédent : 000306; suivant : 000308

[Isolation of HIV-2 from AIDS patient in Ghana and analysis of sero-reactive patterns of Ghanaian sera].

Auteurs : M. Hayami

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RBID : pubmed:2724559

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PubMed: 2724559

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<title xml:lang="en">[Isolation of HIV-2 from AIDS patient in Ghana and analysis of sero-reactive patterns of Ghanaian sera].</title>
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<name sortKey="Hayami, M" sort="Hayami, M" uniqKey="Hayami M" first="M" last="Hayami">M. Hayami</name>
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<title xml:lang="en">[Isolation of HIV-2 from AIDS patient in Ghana and analysis of sero-reactive patterns of Ghanaian sera].</title>
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<name sortKey="Hayami, M" sort="Hayami, M" uniqKey="Hayami M" first="M" last="Hayami">M. Hayami</name>
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<title level="j">Nihon rinsho. Japanese journal of clinical medicine</title>
<idno type="ISSN">0047-1852</idno>
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<keywords scheme="KwdEn" xml:lang="en">
<term>AIDS Serodiagnosis</term>
<term>Acquired Immunodeficiency Syndrome (epidemiology)</term>
<term>Acquired Immunodeficiency Syndrome (microbiology)</term>
<term>Acquired Immunodeficiency Syndrome (transmission)</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Female</term>
<term>Ghana</term>
<term>HIV Seropositivity (epidemiology)</term>
<term>HIV-2 (genetics)</term>
<term>HIV-2 (isolation & purification)</term>
<term>Humans</term>
<term>Male</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Femelle</term>
<term>Ghana</term>
<term>Humains</term>
<term>Mâle</term>
<term>Syndrome d'immunodéficience acquise (microbiologie)</term>
<term>Syndrome d'immunodéficience acquise (transmission)</term>
<term>Syndrome d'immunodéficience acquise (épidémiologie)</term>
<term>Sérodiagnostic du SIDA</term>
<term>Séropositivité VIH (épidémiologie)</term>
<term>VIH-2 (Virus de l'Immunodéficience Humaine de type 2) (génétique)</term>
<term>VIH-2 (Virus de l'Immunodéficience Humaine de type 2) (isolement et purification)</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en">
<term>Ghana</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Acquired Immunodeficiency Syndrome</term>
<term>HIV Seropositivity</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en">
<term>HIV-2</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr">
<term>VIH-2 (Virus de l'Immunodéficience Humaine de type 2)</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en">
<term>HIV-2</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr">
<term>VIH-2 (Virus de l'Immunodéficience Humaine de type 2)</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr">
<term>Syndrome d'immunodéficience acquise</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en">
<term>Acquired Immunodeficiency Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en">
<term>Acquired Immunodeficiency Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Syndrome d'immunodéficience acquise</term>
<term>Séropositivité VIH</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>AIDS Serodiagnosis</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Femelle</term>
<term>Ghana</term>
<term>Humains</term>
<term>Mâle</term>
<term>Sérodiagnostic du SIDA</term>
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<term>Ghana</term>
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<Year>1989</Year>
<Month>07</Month>
<Day>11</Day>
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<DateCompleted>
<Year>1989</Year>
<Month>07</Month>
<Day>11</Day>
</DateCompleted>
<DateRevised>
<Year>2011</Year>
<Month>07</Month>
<Day>27</Day>
</DateRevised>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Print">0047-1852</ISSN>
<JournalIssue CitedMedium="Print">
<Volume>47</Volume>
<Issue>1</Issue>
<PubDate>
<Year>1989</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>Nihon rinsho. Japanese journal of clinical medicine</Title>
<ISOAbbreviation>Nippon Rinsho</ISOAbbreviation>
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<ArticleTitle>[Isolation of HIV-2 from AIDS patient in Ghana and analysis of sero-reactive patterns of Ghanaian sera].</ArticleTitle>
<Pagination>
<MedlinePgn>141-8</MedlinePgn>
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<AuthorList CompleteYN="Y">
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<LastName>Hayami</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
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<Language>jpn</Language>
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<PublicationType UI="D004740">English Abstract</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
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<Country>Japan</Country>
<MedlineTA>Nihon Rinsho</MedlineTA>
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<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D015492" MajorTopicYN="Y">AIDS Serodiagnosis</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000163" MajorTopicYN="N">Acquired Immunodeficiency Syndrome</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName>
<QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005869" MajorTopicYN="N" Type="Geographic">Ghana</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006679" MajorTopicYN="N">HIV Seropositivity</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015498" MajorTopicYN="N">HIV-2</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<OtherID Source="POP">00203853</OtherID>
<OtherAbstract Type="PIP" Language="eng">
<AbstractText>Institute for Virus Research, Kyoto University, and Noguchi Memorial Research Institute in Ghana jointly isolated HIV-2 from a Ghanaian AIDS patient. Ghanaian HIV-2[GH-1] was similar in genomic organization to, but different in Restriction Enzyme Maps from the first isolated case, French LAV-2 (HIV-2ROD). This fact is significant in suggesting multiplicity of HIV-2 virus. HIV-2[GH-1] was different from LAV-2 in its antigenicity of envProtein. Sero-reactive patterns of 125 Ghanaians including 57 AIDS/ARC patients were analyzed using HIV-1, HIV-2, and SIVAGM as antigen. 4 groups were recognized. Group I was HIV-1 only positive; Group II, HIV-2-only positive; Group III, mixed HIV-1 and HIV-2 positive; Group IV reacted to gag protein of HIV-1, HIV-2 and SIVAGM but not to envProtein of any. 24 Ghanians were HIV-1 positive; 38 were HIV-2 positive. 19 out of 20 HIV-2-only positive patients were AIDS/ARC patients. Symptoms and route of infection from HIV-1 and HIV-2 AIDS seem to be similar but HIV-2 is weaker pathologically and in communicability. HIV positive patients were mostly found in the big city such as Accra among young women, especially prostitutes who were migratory "workers" in neighboring countries along the Ivory Coast. Sero-reactive patterns of Ghanaians with SIV as antigen had been known for some time to be different from those of Kenyans in the east coast and those of Gabonese. While KEnyan's antibody was high for HIV-1 and lower for SIVAGM, Ghanian's was higher for SIVAGM than HIV-1. Gabonese's was in between. With discovery of LAV-2 (HIV-2ROD) and Ghanian hybridization with its DNA probe Ghanaian's was found to have among other things VPX and VPR in common with HIV-2ROD.</AbstractText>
</OtherAbstract>
<KeywordList Owner="PIP">
<Keyword MajorTopicYN="Y">Acquired Immunodeficiency Syndrome--transmission</Keyword>
<Keyword MajorTopicYN="Y">Adolescents</Keyword>
<Keyword MajorTopicYN="Y">Adult</Keyword>
<Keyword MajorTopicYN="N">Africa</Keyword>
<Keyword MajorTopicYN="N">Africa South Of The Sahara</Keyword>
<Keyword MajorTopicYN="N">Age Factors</Keyword>
<Keyword MajorTopicYN="N">Asia</Keyword>
<Keyword MajorTopicYN="Y">Comparative Studies</Keyword>
<Keyword MajorTopicYN="N">Demographic Factors</Keyword>
<Keyword MajorTopicYN="N">Developed Countries</Keyword>
<Keyword MajorTopicYN="N">Developing Countries</Keyword>
<Keyword MajorTopicYN="N">Diseases</Keyword>
<Keyword MajorTopicYN="N">Eastern Africa</Keyword>
<Keyword MajorTopicYN="N">Eastern Asia</Keyword>
<Keyword MajorTopicYN="N">English Speaking Africa</Keyword>
<Keyword MajorTopicYN="N">Examinations And Diagnoses</Keyword>
<Keyword MajorTopicYN="N">Ghana</Keyword>
<Keyword MajorTopicYN="Y">Hematologic Tests</Keyword>
<Keyword MajorTopicYN="N">Hiv Infections</Keyword>
<Keyword MajorTopicYN="N">Japan</Keyword>
<Keyword MajorTopicYN="N">Kenya</Keyword>
<Keyword MajorTopicYN="N">Laboratory Examinations And Diagnoses</Keyword>
<Keyword MajorTopicYN="N">Laboratory Procedures</Keyword>
<Keyword MajorTopicYN="N">Population</Keyword>
<Keyword MajorTopicYN="N">Population Characteristics</Keyword>
<Keyword MajorTopicYN="N">Research Methodology</Keyword>
<Keyword MajorTopicYN="N">Studies</Keyword>
<Keyword MajorTopicYN="N">Viral Diseases</Keyword>
<Keyword MajorTopicYN="N">Western Africa</Keyword>
<Keyword MajorTopicYN="N">Youth</Keyword>
</KeywordList>
<GeneralNote Owner="PIP">TJ: NIPPON RINSHO.</GeneralNote>
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