Facilitators and barriers to antiretroviral therapy adherence among adolescents in Ghana.
Identifieur interne : 000306 ( PubMed/Curation ); précédent : 000305; suivant : 000307Facilitators and barriers to antiretroviral therapy adherence among adolescents in Ghana.
Auteurs : Daniel Na Ankrah [Ghana] ; Ellen S. Koster [Ghana] ; Aukje K. Mantel-Teeuwisse [Ghana] ; Daniel K. Arhinful [Ghana] ; Irene A. Agyepong [Ghana] ; Margaret Lartey [Ghana]Source :
- Patient preference and adherence [ 1177-889X ] ; 2016.
Abstract
Adherence to antiretroviral therapy (ART) is known to be challenging among adolescents living with HIV/AIDS, notwithstanding the life-saving importance of this therapy. Of the global total number of adolescents living with HIV in 2013, 83% reside in sub-Saharan Africa. The study aimed to identify facilitators of and barriers to antiretroviral treatment adherence among adolescents in Ghana.
DOI: 10.2147/PPA.S96691
PubMed: 27042024
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Koster</name><affiliation wicri:level="1"><nlm:affiliation>Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, the Netherlands, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, the Netherlands, Accra</wicri:regionArea></affiliation></author><author><name sortKey="Mantel Teeuwisse, Aukje K" sort="Mantel Teeuwisse, Aukje K" uniqKey="Mantel Teeuwisse A" first="Aukje K" last="Mantel-Teeuwisse">Aukje K. Mantel-Teeuwisse</name><affiliation wicri:level="1"><nlm:affiliation>Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, the Netherlands, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, the Netherlands, Accra</wicri:regionArea></affiliation></author><author><name sortKey="Arhinful, Daniel K" sort="Arhinful, Daniel K" uniqKey="Arhinful D" first="Daniel K" last="Arhinful">Daniel K. Arhinful</name><affiliation wicri:level="1"><nlm:affiliation>Noguchi Memorial Institute for Medical Research, University of Ghana (Legon), Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Noguchi Memorial Institute for Medical Research, University of Ghana (Legon), Accra</wicri:regionArea></affiliation></author><author><name sortKey="Agyepong, Irene A" sort="Agyepong, Irene A" uniqKey="Agyepong I" first="Irene A" last="Agyepong">Irene A. Agyepong</name><affiliation wicri:level="1"><nlm:affiliation>Health Policy, Planning and Management, University of Ghana School of Public Health, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Health Policy, Planning and Management, University of Ghana School of Public Health, Accra</wicri:regionArea></affiliation></author><author><name sortKey="Lartey, Margaret" sort="Lartey, Margaret" uniqKey="Lartey M" first="Margaret" last="Lartey">Margaret Lartey</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Ghana Medical School, Accra, Ghana; Department of Medicine and Therapeutics, Korle-Bu Teaching Hospital, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Medicine, University of Ghana Medical School, Accra, Ghana; Department of Medicine and Therapeutics, Korle-Bu Teaching Hospital, Accra</wicri:regionArea></affiliation></author></analytic><series><title level="j">Patient preference and adherence</title><idno type="ISSN">1177-889X</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Adherence to antiretroviral therapy (ART) is known to be challenging among adolescents living with HIV/AIDS, notwithstanding the life-saving importance of this therapy. Of the global total number of adolescents living with HIV in 2013, 83% reside in sub-Saharan Africa. The study aimed to identify facilitators of and barriers to antiretroviral treatment adherence among adolescents in Ghana.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">27042024</PMID><DateCreated><Year>2016</Year><Month>04</Month><Day>04</Day></DateCreated><DateCompleted><Year>2016</Year><Month>04</Month><Day>04</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>20</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Print">1177-889X</ISSN><JournalIssue CitedMedium="Print"><Volume>10</Volume><PubDate><Year>2016</Year></PubDate></JournalIssue><Title>Patient preference and adherence</Title><ISOAbbreviation>Patient Prefer Adherence</ISOAbbreviation></Journal><ArticleTitle>Facilitators and barriers to antiretroviral therapy adherence among adolescents in Ghana.</ArticleTitle><Pagination><MedlinePgn>329-37</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.2147/PPA.S96691</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Adherence to antiretroviral therapy (ART) is known to be challenging among adolescents living with HIV/AIDS, notwithstanding the life-saving importance of this therapy. Of the global total number of adolescents living with HIV in 2013, 83% reside in sub-Saharan Africa. The study aimed to identify facilitators of and barriers to antiretroviral treatment adherence among adolescents in Ghana.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A cross-sectional qualitative study using semi-structured interviews for data collection was carried out among adolescents (aged 12-19 years) at the adolescents HIV clinic at the Korle-Bu Teaching Hospital in Ghana. Predominantly open-ended questions relating to ART were used. Interviews were done until saturation. In total, 19 interviews were conducted. Analysis was done manually to maintain proximity with the text.</AbstractText><AbstractText Label="FINDINGS" NlmCategory="RESULTS">The main facilitators were support from health care providers, parental support, patient's knowledge of disease and self-motivation, patient's perceived positive outcomes, and dispensed formulation. The identified barriers were patient's forgetfulness to take medicines, perceived stigmatization due to disclosure, financial barriers, and adverse effects of ART. Support from health care workers was the most frequently mentioned facilitator, and patient's forgetfulness and perceived stigmatization after disclosure were the most frequently mentioned barriers. Self-motivation (knowledge induced) to adhere to treatment was a specific facilitator among older adolescents.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Continuous information provision in addition to unflinching support from health care workers and parents or guardians may improve adherence among adolescents. Also, interventions to reduce patient forgetfulness may be beneficial. A multi-sectorial approach would be needed to address adolescent disclosure of HIV/AIDS status.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ankrah</LastName><ForeName>Daniel Na</ForeName><Initials>DN</Initials><AffiliationInfo><Affiliation>Pharmacy Department, Korle-Bu Teaching Hospital, Accra, Ghana, Accra, Ghana; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, the Netherlands, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koster</LastName><ForeName>Ellen S</ForeName><Initials>ES</Initials><AffiliationInfo><Affiliation>Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, the Netherlands, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mantel-Teeuwisse</LastName><ForeName>Aukje K</ForeName><Initials>AK</Initials><AffiliationInfo><Affiliation>Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, the Netherlands, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arhinful</LastName><ForeName>Daniel K</ForeName><Initials>DK</Initials><AffiliationInfo><Affiliation>Noguchi Memorial Institute for Medical Research, University of Ghana (Legon), Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Agyepong</LastName><ForeName>Irene A</ForeName><Initials>IA</Initials><AffiliationInfo><Affiliation>Health Policy, Planning and Management, University of Ghana School of Public Health, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lartey</LastName><ForeName>Margaret</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Ghana Medical School, Accra, Ghana; Department of Medicine and Therapeutics, Korle-Bu Teaching Hospital, Accra, Ghana.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>03</Month><Day>15</Day></ArticleDate></Article><MedlineJournalInfo><Country>New Zealand</Country><MedlineTA>Patient Prefer Adherence</MedlineTA><NlmUniqueID>101475748</NlmUniqueID><ISSNLinking>1177-889X</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>J Med Internet Res. 2012 Apr 05;14(2):e51</RefSource><PMID Version="1">22481246</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>AIDS Patient Care STDS. 2006 Jun;20(6):438-44</RefSource><PMID Version="1">16789857</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Aliment Pharmacol Ther. 2005 May 15;21(10):1255-62</RefSource><PMID Version="1">15882247</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Int AIDS Soc. 2014 Mar 10;17:18866</RefSource><PMID Version="1">24629845</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Infect Dis. 2009 Feb 15;48(4):484-8</RefSource><PMID Version="1">19140758</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Salud Publica Mex. 2003 May-Jun;45(3):191-7</RefSource><PMID Version="1">12870420</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Adolesc Health. 2000 Dec;27(6):391-8</RefSource><PMID Version="1">11090741</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Pediatr Adolesc Med. 2003 Mar;157(3):249-55</RefSource><PMID Version="1">12622674</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Allergy Clin Immunol. 2003 Sep;112(3):489-94</RefSource><PMID Version="1">13679805</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMJ. 2000 Jan 8;320(7227):114-6</RefSource><PMID Version="1">10625273</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Consult Clin Psychol. 1994 Jun;62(3):603-10</RefSource><PMID Version="1">8063987</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Ther. 2001 Aug;23(8):1296-310</RefSource><PMID Version="1">11558866</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Paediatr Child Health. 2008 Jan;13(1):19-24</RefSource><PMID Version="1">19119348</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Top HIV Med. 2009 Feb-Mar;17(1):14-25</RefSource><PMID Version="1">19270345</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Patient Educ Couns. 2004 Jul;54(1):55-60</RefSource><PMID Version="1">15210260</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>AIDS Care. 2007 Jan;19(1):28-33</RefSource><PMID Version="1">17129855</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Ther. 1999 Jun;21(6):1074-90; 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discussion 317-41</RefSource><PMID Version="1">16921915</PMID></CommentsCorrections></CommentsCorrectionsList><OtherID Source="NLM">PMC4801129</OtherID><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">disclosure</Keyword><Keyword MajorTopicYN="N">forgetfulness</Keyword><Keyword MajorTopicYN="N">parental support</Keyword><Keyword MajorTopicYN="N">qualitative study</Keyword><Keyword MajorTopicYN="N">stigmatization</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>4</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>4</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>4</Month><Day>5</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27042024</ArticleId><ArticleId IdType="doi">10.2147/PPA.S96691</ArticleId><ArticleId IdType="pii">ppa-10-329</ArticleId><ArticleId IdType="pmc">PMC4801129</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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