Le SIDA au Ghana (serveur d'exploration)

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Prevalence of hepatitis B virus co-infection among HIV-seropositive persons attending antiretroviral clinics in the Eastern Region of Ghana.

Identifieur interne : 000042 ( PubMed/Curation ); précédent : 000041; suivant : 000043

Prevalence of hepatitis B virus co-infection among HIV-seropositive persons attending antiretroviral clinics in the Eastern Region of Ghana.

Auteurs : Gideon Kye-Duodu [Ghana] ; Priscillia Nortey [Ghana] ; Keziah Malm [Ghana] ; Kofi Mensah Nyarko [Ghana] ; Samuel Oko Sackey [Ghana] ; Sampson Ofori [Ghana] ; Edwin Andrews Afari [Ghana]

Source :

RBID : pubmed:28210375

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English descriptors

Abstract

Hepatitis B and HIV infections are endemic in sub-Saharan Africa including Ghana. Understanding the extent of the co-infection is critical to the optimal care of persons living with HIV and AIDS (PLHIV). We determined the prevalence and risk factors of HBV co-infection in PLHIV and assessed the knowledge of health care workers (HCW) in Antiretroviral Therapy (ART) clinics regarding the co-infection.

DOI: 10.11604/pamj.supp.2016.25.1.6172
PubMed: 28210375

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<div type="abstract" xml:lang="en">Hepatitis B and HIV infections are endemic in sub-Saharan Africa including Ghana. Understanding the extent of the co-infection is critical to the optimal care of persons living with HIV and AIDS (PLHIV). We determined the prevalence and risk factors of HBV co-infection in PLHIV and assessed the knowledge of health care workers (HCW) in Antiretroviral Therapy (ART) clinics regarding the co-infection.</div>
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<ArticleTitle>Prevalence of hepatitis B virus co-infection among HIV-seropositive persons attending antiretroviral clinics in the Eastern Region of Ghana.</ArticleTitle>
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<AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Hepatitis B and HIV infections are endemic in sub-Saharan Africa including Ghana. Understanding the extent of the co-infection is critical to the optimal care of persons living with HIV and AIDS (PLHIV). We determined the prevalence and risk factors of HBV co-infection in PLHIV and assessed the knowledge of health care workers (HCW) in Antiretroviral Therapy (ART) clinics regarding the co-infection.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A cross sectional study was conducted in five ART clinics to obtain data from a systematic random sample of PLHIV in the Eastern region of Ghana from March to June 2012. We used self-administered questionnaires to assess knowledge of HCW on knowledge and management of the co-infection. Descriptive statistics and logistic regression models were used for analysis at 5% significance level.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Of 320 PLHIV recruited into study, with median age of 40 years (IQR: 33-50 years), 28 tested positive for HBsAg giving an overall prevalence of 8.8%. There were significant associations between HBV infection and being an adult (p=0.004), increasing serum ALT levels (p=0.002) and partner with history of HBV infection (p=0.010). HCW obtained 84.2% (SD± 20.53; 95% CI: 89-98.1) and 53.1% (SD± 35.06; 95% CI: 13.0-88.9) in the "general knowledge" and "management practice" indexes respectively.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Prevalence of HBV-HIV co-infection was relatively high among PLHIV in Eastern region. Knowledge of HCW on management practices of HBV-HIV co-infection and HBV vaccination coverage among PLHIV were found to be relatively low. Regular trainings of HCW and a HBV vaccination programme targeted at PLHIV should be considered.</AbstractText>
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<CommentsCorrections RefType="Cites">
<RefSource>J Glob Infect Dis. 2011 Jul;3(3):269-74</RefSource>
<PMID Version="1">21887060</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>AIDS. 2009 Sep 10;23(14):1881-9</RefSource>
<PMID Version="1">19550291</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>J Acquir Immune Defic Syndr. 2008 Aug 15;48(5):590-8</RefSource>
<PMID Version="1">18645512</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>BMC Public Health. 2008 Dec 19;8:416</RefSource>
<PMID Version="1">19099553</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Jpn J Infect Dis. 2005 Feb;58(1):15-9</RefSource>
<PMID Version="1">15728984</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>AIDS. 2005 Mar 24;19(6):593-601</RefSource>
<PMID Version="1">15802978</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D060085" MajorTopicYN="N">Coinfection</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005869" MajorTopicYN="N">Ghana</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015658" MajorTopicYN="N">HIV Infections</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D007722" MajorTopicYN="Y">Health Knowledge, Attitudes, Practice</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006282" MajorTopicYN="N">Health Personnel</DescriptorName>
<QualifierName UI="Q000592" MajorTopicYN="Y">standards</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006509" MajorTopicYN="N">Hepatitis B</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D017325" MajorTopicYN="N">Hepatitis B Vaccines</DescriptorName>
<QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D016015" MajorTopicYN="N">Logistic Models</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D011795" MajorTopicYN="N">Surveys and Questionnaires</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
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<Keyword MajorTopicYN="Y">Ghana</Keyword>
<Keyword MajorTopicYN="Y">Human Immunodeficiency Virus</Keyword>
<Keyword MajorTopicYN="Y">co-infection</Keyword>
<Keyword MajorTopicYN="Y">hepatitis B virus</Keyword>
<Keyword MajorTopicYN="Y">risk factors</Keyword>
</KeywordList>
<CoiStatement>The authors declare no competing interest.</CoiStatement>
</MedlineCitation>
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<Year>2015</Year>
<Month>01</Month>
<Day>22</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted">
<Year>2016</Year>
<Month>06</Month>
<Day>06</Day>
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<PubMedPubDate PubStatus="entrez">
<Year>2017</Year>
<Month>2</Month>
<Day>18</Day>
<Hour>6</Hour>
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<Day>18</Day>
<Hour>6</Hour>
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<PubMedPubDate PubStatus="medline">
<Year>2017</Year>
<Month>3</Month>
<Day>23</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PublicationStatus>epublish</PublicationStatus>
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<ArticleId IdType="doi">10.11604/pamj.supp.2016.25.1.6172</ArticleId>
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<ArticleId IdType="pmc">PMC5292113</ArticleId>
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