Deferred donor care in a regional hospital blood center in Ghana.
Identifieur interne : 000261 ( PubMed/Corpus ); précédent : 000260; suivant : 000262Deferred donor care in a regional hospital blood center in Ghana.
Auteurs : Jean-Pierre Allain ; Ohene Opare-Sem ; Francis Sarkodie ; Rabiatu Rahman ; Shirley Owusu-OforiSource :
- Transfusion [ 1537-2995 ] ; 2009.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Appointments and Schedules, Blood Donors (statistics & numerical data), Communicable Diseases (blood), Communicable Diseases (diagnosis), Communicable Diseases (epidemiology), Communicable Diseases (therapy), Delivery of Health Care (economics), Delivery of Health Care (methods), Delivery of Health Care (statistics & numerical data), Follow-Up Studies, Ghana (epidemiology), Hematologic Tests (statistics & numerical data), Hospitals (statistics & numerical data), Humans, Middle Aged, Patient Selection, Regional Medical Programs (economics), Regional Medical Programs (statistics & numerical data), Seroepidemiologic Studies, Young Adult.
- MESH :
- geographic , epidemiology : Ghana.
- blood : Communicable Diseases.
- diagnosis : Communicable Diseases.
- economics : Delivery of Health Care, Regional Medical Programs.
- epidemiology : Communicable Diseases.
- methods : Delivery of Health Care.
- statistics & numerical data : Blood Donors, Delivery of Health Care, Hematologic Tests, Hospitals, Regional Medical Programs.
- therapy : Communicable Diseases.
- Adolescent, Adult, Aged, Aged, 80 and over, Appointments and Schedules, Follow-Up Studies, Humans, Middle Aged, Patient Selection, Seroepidemiologic Studies, Young Adult.
Abstract
In sub-Saharan Africa, the viral marker burden in blood donor populations ranges between 10 and 30 percent. Deferred donors constitute a rare population of asymptomatic human immunodeficiency virus (HIV)- and hepatitis B virus (HBV)-infected individuals with high likelihood of long survival if cared for. Deferred donor care provides an opportunity for a public health impact on highly pathogenic infections.
DOI: 10.1111/j.1537-2995.2008.02055.x
PubMed: 19170991
Links to Exploration step
pubmed:19170991Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Deferred donor care in a regional hospital blood center in Ghana.</title><author><name sortKey="Allain, Jean Pierre" sort="Allain, Jean Pierre" uniqKey="Allain J" first="Jean-Pierre" last="Allain">Jean-Pierre Allain</name><affiliation><nlm:affiliation>Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge Blood Centre, Long Road, Cambridge, UK. jpa1000@cam.ac.uk</nlm:affiliation></affiliation></author><author><name sortKey="Opare Sem, Ohene" sort="Opare Sem, Ohene" uniqKey="Opare Sem O" first="Ohene" last="Opare-Sem">Ohene Opare-Sem</name></author><author><name sortKey="Sarkodie, Francis" sort="Sarkodie, Francis" uniqKey="Sarkodie F" first="Francis" last="Sarkodie">Francis Sarkodie</name></author><author><name sortKey="Rahman, Rabiatu" sort="Rahman, Rabiatu" uniqKey="Rahman R" first="Rabiatu" last="Rahman">Rabiatu Rahman</name></author><author><name sortKey="Owusu Ofori, Shirley" sort="Owusu Ofori, Shirley" uniqKey="Owusu Ofori S" first="Shirley" last="Owusu-Ofori">Shirley Owusu-Ofori</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="RBID">pubmed:19170991</idno><idno type="pmid">19170991</idno><idno type="doi">10.1111/j.1537-2995.2008.02055.x</idno><idno type="wicri:Area/PubMed/Corpus">000261</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000261</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Deferred donor care in a regional hospital blood center in Ghana.</title><author><name sortKey="Allain, Jean Pierre" sort="Allain, Jean Pierre" uniqKey="Allain J" first="Jean-Pierre" last="Allain">Jean-Pierre Allain</name><affiliation><nlm:affiliation>Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge Blood Centre, Long Road, Cambridge, UK. jpa1000@cam.ac.uk</nlm:affiliation></affiliation></author><author><name sortKey="Opare Sem, Ohene" sort="Opare Sem, Ohene" uniqKey="Opare Sem O" first="Ohene" last="Opare-Sem">Ohene Opare-Sem</name></author><author><name sortKey="Sarkodie, Francis" sort="Sarkodie, Francis" uniqKey="Sarkodie F" first="Francis" last="Sarkodie">Francis Sarkodie</name></author><author><name sortKey="Rahman, Rabiatu" sort="Rahman, Rabiatu" uniqKey="Rahman R" first="Rabiatu" last="Rahman">Rabiatu Rahman</name></author><author><name sortKey="Owusu Ofori, Shirley" sort="Owusu Ofori, Shirley" uniqKey="Owusu Ofori S" first="Shirley" last="Owusu-Ofori">Shirley Owusu-Ofori</name></author></analytic><series><title level="j">Transfusion</title><idno type="eISSN">1537-2995</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Appointments and Schedules</term><term>Blood Donors (statistics & numerical data)</term><term>Communicable Diseases (blood)</term><term>Communicable Diseases (diagnosis)</term><term>Communicable Diseases (epidemiology)</term><term>Communicable Diseases (therapy)</term><term>Delivery of Health Care (economics)</term><term>Delivery of Health Care (methods)</term><term>Delivery of Health Care (statistics & numerical data)</term><term>Follow-Up Studies</term><term>Ghana (epidemiology)</term><term>Hematologic Tests (statistics & numerical data)</term><term>Hospitals (statistics & numerical data)</term><term>Humans</term><term>Middle Aged</term><term>Patient Selection</term><term>Regional Medical Programs (economics)</term><term>Regional Medical Programs (statistics & numerical data)</term><term>Seroepidemiologic Studies</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Ghana</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Communicable Diseases</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Communicable Diseases</term></keywords><keywords scheme="MESH" qualifier="economics" xml:lang="en"><term>Delivery of Health Care</term><term>Regional Medical Programs</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Communicable Diseases</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Delivery of Health Care</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Blood Donors</term><term>Delivery of Health Care</term><term>Hematologic Tests</term><term>Hospitals</term><term>Regional Medical Programs</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Communicable Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Appointments and Schedules</term><term>Follow-Up Studies</term><term>Humans</term><term>Middle Aged</term><term>Patient Selection</term><term>Seroepidemiologic Studies</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In sub-Saharan Africa, the viral marker burden in blood donor populations ranges between 10 and 30 percent. Deferred donors constitute a rare population of asymptomatic human immunodeficiency virus (HIV)- and hepatitis B virus (HBV)-infected individuals with high likelihood of long survival if cared for. Deferred donor care provides an opportunity for a public health impact on highly pathogenic infections.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19170991</PMID><DateCreated><Year>2009</Year><Month>04</Month><Day>01</Day></DateCreated><DateCompleted><Year>2009</Year><Month>05</Month><Day>01</Day></DateCompleted><DateRevised><Year>2009</Year><Month>04</Month><Day>01</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1537-2995</ISSN><JournalIssue CitedMedium="Internet"><Volume>49</Volume><Issue>4</Issue><PubDate><Year>2009</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Transfusion</Title><ISOAbbreviation>Transfusion</ISOAbbreviation></Journal><ArticleTitle>Deferred donor care in a regional hospital blood center in Ghana.</ArticleTitle><Pagination><MedlinePgn>669-75</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/j.1537-2995.2008.02055.x</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">In sub-Saharan Africa, the viral marker burden in blood donor populations ranges between 10 and 30 percent. Deferred donors constitute a rare population of asymptomatic human immunodeficiency virus (HIV)- and hepatitis B virus (HBV)-infected individuals with high likelihood of long survival if cared for. Deferred donor care provides an opportunity for a public health impact on highly pathogenic infections.</AbstractText><AbstractText Label="STUDY DESIGN AND METHODS" NlmCategory="METHODS">Between 2004 and 2007, all candidate donors deferred before donation for reactivity of anti-HIV, hepatitis C virus antibody (anti-HCV), and hepatitis B virus surface antigen (HBsAg) rapid tests were informed and referred to a donor care program consisting of test confirmation, information, counseling, and potential referral for follow-up and therapy. Dedicated trained nurses supervised the program including alanine aminotransferase (ALT) level testing to identify liver disease.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In a 4-year period 51,100 donors were screened and 5778, 1578, and 227 candidate donors were deferred for reactivity to HBV, HIV, or HCV serologic markers, respectively. The rates of entry into the donor care program were 48, 14.3, and 22 percent of deferred donors, respectively. A total of 83 of 210 HBsAg-positive donors with elevated ALT levels were referred and 66 received antiviral treatment. A total of 89 of 516 confirmed anti-HIV-positive donors were referred to the hospital acquired immune deficiency syndrome clinic for follow-up.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">With little additional expense, the deferred donor care program identified asymptomatic infections with high odds of benefiting from monitoring and therapy. In the local circumstances, this public health-limited but definite impact was permitted by the rapid-test pre-donation screening, and this impact could be increased if more resources were available.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Allain</LastName><ForeName>Jean-Pierre</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge Blood Centre, Long Road, Cambridge, UK. jpa1000@cam.ac.uk</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Opare-Sem</LastName><ForeName>Ohene</ForeName><Initials>O</Initials></Author><Author ValidYN="Y"><LastName>Sarkodie</LastName><ForeName>Francis</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Rahman</LastName><ForeName>Rabiatu</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Owusu-Ofori</LastName><ForeName>Shirley</ForeName><Initials>S</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D023362">Evaluation Studies</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2008</Year><Month>01</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Transfusion</MedlineTA><NlmUniqueID>0417360</NlmUniqueID><ISSNLinking>0041-1132</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001071" MajorTopicYN="N">Appointments and Schedules</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001782" MajorTopicYN="Y">Blood Donors</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003141" MajorTopicYN="N">Communicable Diseases</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003695" MajorTopicYN="Y">Delivery of Health Care</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005869" MajorTopicYN="N" Type="Geographic">Ghana</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006403" MajorTopicYN="N">Hematologic Tests</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006761" MajorTopicYN="N">Hospitals</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018579" MajorTopicYN="Y">Patient Selection</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012041" MajorTopicYN="N">Regional Medical Programs</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016036" MajorTopicYN="N">Seroepidemiologic Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>1</Month><Day>28</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>1</Month><Day>28</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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