Le SIDA au Ghana (serveur d'exploration)

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Crystalluria in HIV/AIDS patients on highly active anti-retroviral therapy in the Kumasi metropolis; a cross sectional study.

Identifieur interne : 000348 ( PubMed/Checkpoint ); précédent : 000347; suivant : 000349

Crystalluria in HIV/AIDS patients on highly active anti-retroviral therapy in the Kumasi metropolis; a cross sectional study.

Auteurs : Richard K D. Ephraim [Ghana] ; Ruth C. Brenyah [Ghana] ; Richmond Osei [Ghana] ; Bright D. Bossipe [Ghana] ; Prince Adoba [Ghana] ; Derick N M. Osakunor [Ghana] ; Hope Agbodzakey [Ghana]

Source :

RBID : pubmed:25538371

Abstract

Crystalluria is associated with some highly active anti-retroviral therapies (HAART's) used in the management of HIV/AIDS.

DOI: 10.4103/0300-1652.144709
PubMed: 25538371


Affiliations:


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Le document en format XML

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<ArticleTitle>Crystalluria in HIV/AIDS patients on highly active anti-retroviral therapy in the Kumasi metropolis; a cross sectional study.</ArticleTitle>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Crystalluria is associated with some highly active anti-retroviral therapies (HAART's) used in the management of HIV/AIDS.</AbstractText>
<AbstractText Label="AIMS" NlmCategory="OBJECTIVE">This study used light microscopy to establish the prevalence of crystalluria among HIV/AIDS patients on HAART and identified the routine crystals present in their urine.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">In this simple randomised cross-sectional study, 200 HIV/AIDS participants, comprising 150 on HAART and 50 HAART-naïve were recruited from the HIV clinic at the Komfo Anokye Teaching Hospital (KATH). Urine and blood samples were collected, for urinalysis and the determination of the CD4 count, respectively. A well-structured pre-tested questionnaire was used to obtain socio-demographic data and clinical history of the participants.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The prevalence of crystalluria was higher among HIV-infected persons on HAART than those not on HAART (6.7% vs 4%; P = 0.733). Calcium oxalate and triple phosphate crystals were the crystal types present in their urine (3.5% and 2.5%, respectively) and was present only in HIV subjects on first line of treatment (without protease inhibitors). Participants aged between 40-50 years and those with hypersthenuria and acidic urine had the highest amount of crystalluria (41.6%, 83.3%, and 58.3%, respectively).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">HAART is associated with crystalluria in HIV patients. Light microscopy will be of disgnostic value in resource limited settings.</AbstractText>
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<CommentsCorrections RefType="Cites">
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<RefSource>Clin Sci (Lond). 1981 Apr;60(4):411-8</RefSource>
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<RefSource>Arch Esp Urol. 2006 Jul-Aug;59(6):653-9</RefSource>
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