Crystalluria in HIV/AIDS patients on highly active anti-retroviral therapy in the Kumasi metropolis; a cross sectional study.
Identifieur interne : 000348 ( PubMed/Checkpoint ); précédent : 000347; suivant : 000349Crystalluria in HIV/AIDS patients on highly active anti-retroviral therapy in the Kumasi metropolis; a cross sectional study.
Auteurs : Richard K D. Ephraim [Ghana] ; Ruth C. Brenyah [Ghana] ; Richmond Osei [Ghana] ; Bright D. Bossipe [Ghana] ; Prince Adoba [Ghana] ; Derick N M. Osakunor [Ghana] ; Hope Agbodzakey [Ghana]Source :
- Nigerian medical journal : journal of the Nigeria Medical Association [ 0300-1652 ] ; 2014.
Abstract
Crystalluria is associated with some highly active anti-retroviral therapies (HAART's) used in the management of HIV/AIDS.
DOI: 10.4103/0300-1652.144709
PubMed: 25538371
Affiliations:
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<front><div type="abstract" xml:lang="en">Crystalluria is associated with some highly active anti-retroviral therapies (HAART's) used in the management of HIV/AIDS.</div>
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<pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">25538371</PMID>
<DateCreated><Year>2014</Year>
<Month>12</Month>
<Day>24</Day>
</DateCreated>
<DateCompleted><Year>2014</Year>
<Month>12</Month>
<Day>24</Day>
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<Issue>6</Issue>
<PubDate><Year>2014</Year>
<Month>Nov</Month>
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<Title>Nigerian medical journal : journal of the Nigeria Medical Association</Title>
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<ArticleTitle>Crystalluria in HIV/AIDS patients on highly active anti-retroviral therapy in the Kumasi metropolis; a cross sectional study.</ArticleTitle>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Crystalluria is associated with some highly active anti-retroviral therapies (HAART's) used in the management of HIV/AIDS.</AbstractText>
<AbstractText Label="AIMS" NlmCategory="OBJECTIVE">This study used light microscopy to establish the prevalence of crystalluria among HIV/AIDS patients on HAART and identified the routine crystals present in their urine.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">In this simple randomised cross-sectional study, 200 HIV/AIDS participants, comprising 150 on HAART and 50 HAART-naïve were recruited from the HIV clinic at the Komfo Anokye Teaching Hospital (KATH). Urine and blood samples were collected, for urinalysis and the determination of the CD4 count, respectively. A well-structured pre-tested questionnaire was used to obtain socio-demographic data and clinical history of the participants.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The prevalence of crystalluria was higher among HIV-infected persons on HAART than those not on HAART (6.7% vs 4%; P = 0.733). Calcium oxalate and triple phosphate crystals were the crystal types present in their urine (3.5% and 2.5%, respectively) and was present only in HIV subjects on first line of treatment (without protease inhibitors). Participants aged between 40-50 years and those with hypersthenuria and acidic urine had the highest amount of crystalluria (41.6%, 83.3%, and 58.3%, respectively).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">HAART is associated with crystalluria in HIV patients. Light microscopy will be of disgnostic value in resource limited settings.</AbstractText>
</Abstract>
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<AffiliationInfo><Affiliation>Department of Laboratory Technology, Medical Laboratory Division, University of Cape Coast, Cape Coast, Ghana.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Clinical Microbiology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Molecular Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.</Affiliation>
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<Keyword MajorTopicYN="N">highly active antiretroviral therapy</Keyword>
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