Causes of death and factors associated with early mortality of HIV-infected adults admitted to Korle-Bu Teaching Hospital.
Identifieur interne : 000B91 ( Ncbi/Merge ); précédent : 000B90; suivant : 000B92Causes of death and factors associated with early mortality of HIV-infected adults admitted to Korle-Bu Teaching Hospital.
Auteurs : Adriana Saavedra [États-Unis] ; Nia Campinha-Bacote [États-Unis] ; Maurice Hajjar [États-Unis] ; Ernest Kenu ; Fizza Syeda Gillani [États-Unis] ; Adjoa Obo-Akwa [Ghana] ; Margaret Lartey [Ghana] ; Awewura Kwara [États-Unis]Source :
- The Pan African medical journal [ 1937-8688 ] ; 2017.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Agents antiVIH (administration et posologie), Cause de décès, Facteurs temps, Femelle, Ghana (épidémiologie), Hospitalisation, Humains, Hôpitaux d'enseignement, Infections opportunistes liées au SIDA (épidémiologie), Infections à VIH (mortalité), Infections à VIH (traitement médicamenteux), Jeune adulte, Mortalité hospitalière, Mâle, Thérapie antirétrovirale hautement active (), Études rétrospectives.
- MESH :
- administration et posologie : Agents antiVIH.
- mortalité : Infections à VIH.
- traitement médicamenteux : Infections à VIH.
- épidémiologie : Ghana, Infections opportunistes liées au SIDA.
- Adolescent, Adulte, Adulte d'âge moyen, Cause de décès, Facteurs temps, Femelle, Hospitalisation, Humains, Hôpitaux d'enseignement, Jeune adulte, Mortalité hospitalière, Mâle, Thérapie antirétrovirale hautement active, Études rétrospectives.
English descriptors
- KwdEn :
- AIDS-Related Opportunistic Infections (epidemiology), Adolescent, Adult, Anti-HIV Agents (administration & dosage), Antiretroviral Therapy, Highly Active (methods), Cause of Death, Female, Ghana (epidemiology), HIV Infections (drug therapy), HIV Infections (mortality), Hospital Mortality, Hospitalization, Hospitals, Teaching, Humans, Male, Middle Aged, Retrospective Studies, Time Factors, Young Adult.
- MESH :
- chemical , administration & dosage : Anti-HIV Agents.
- drug therapy : HIV Infections.
- epidemiology : AIDS-Related Opportunistic Infections, Ghana.
- methods : Antiretroviral Therapy, Highly Active.
- mortality : HIV Infections.
- Adolescent, Adult, Cause of Death, Female, Hospital Mortality, Hospitalization, Hospitals, Teaching, Humans, Male, Middle Aged, Retrospective Studies, Time Factors, Young Adult.
Abstract
This study sought to identify common causes of death as well as the factors associated with the high inpatient mortality rate of HIV-infected patients at the Korle-Bu Teaching Hospital (KBTH).
DOI: 10.11604/pamj.2017.27.48.8917
PubMed: 28819470
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pubmed:28819470Le document en format XML
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(épidémiologie)</term><term>Infections à VIH (mortalité)</term><term>Infections à VIH (traitement médicamenteux)</term><term>Jeune adulte</term><term>Mortalité hospitalière</term><term>Mâle</term><term>Thérapie antirétrovirale hautement active ()</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Anti-HIV Agents</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Agents antiVIH</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>AIDS-Related Opportunistic Infections</term><term>Ghana</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Antiretroviral Therapy, Highly Active</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>HIV 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temps</term><term>Femelle</term><term>Hospitalisation</term><term>Humains</term><term>Hôpitaux d'enseignement</term><term>Jeune adulte</term><term>Mortalité hospitalière</term><term>Mâle</term><term>Thérapie antirétrovirale hautement active</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study sought to identify common causes of death as well as the factors associated with the high inpatient mortality rate of HIV-infected patients at the Korle-Bu Teaching Hospital (KBTH).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28819470</PMID><DateCreated><Year>2017</Year><Month>08</Month><Day>18</Day></DateCreated><DateCompleted><Year>2017</Year><Month>09</Month><Day>04</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>04</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1937-8688</ISSN><JournalIssue CitedMedium="Internet"><Volume>27</Volume><PubDate><Year>2017</Year></PubDate></JournalIssue><Title>The Pan African medical journal</Title><ISOAbbreviation>Pan Afr Med J</ISOAbbreviation></Journal><ArticleTitle>Causes of death and factors associated with early mortality of HIV-infected adults admitted to Korle-Bu Teaching Hospital.</ArticleTitle><Pagination><MedlinePgn>48</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.11604/pamj.2017.27.48.8917</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">This study sought to identify common causes of death as well as the factors associated with the high inpatient mortality rate of HIV-infected patients at the Korle-Bu Teaching Hospital (KBTH).</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The retrospective study reviewed the medical records of 547 HIV-infected adults aged 18 years or older admitted to the KBTH between the months of January 2012 and October 2013. Using standardized abstraction forms, clinical and demographic data of eligible patients was collected. Data was summarized using descriptive statistics. Demographic and clinical characteristics of patients who died within 7 days (early) and after (late) admission were compared using Rank Sum tests or Chi-square tests.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Of 547 eligible patients during the period, 222 (40.6%) died during hospitalization, with 124 (55.9%) of them dying within a week of admission. Of the 222 patients who died, 190 (85.6%) were previously known HIV-positive. Yet, 141 (63.5%) of the 222 patients who died had no prior highly active antiretroviral therapy (HAART). The most common admitting diagnoses were anemia (34.2%), cerebral toxoplasmosis (29.3%), and pneumonia (25.7%); the most common causes of death were tuberculosis (34.7%), anemia (30.2%) and cerebral toxoplasmosis (27.5%). Tuberculosis was the only factor significantly associated with early death (P<0.05).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The inpatient mortality rate among HIV-infected adults admitted to the KBTH is high. A majority of the patients were not receiving HAART despite known HIV diagnosis. Earlier initiation of HAART may lower the risk of opportunistic infections and HIV mortality rates. Additionally, a high index of suspicion and initiation of empiric treatment for TB may reduce early deaths.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Saavedra</LastName><ForeName>Adriana</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Brown University, Providence, RI, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Campinha-Bacote</LastName><ForeName>Nia</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Brown University, Providence, RI, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hajjar</LastName><ForeName>Maurice</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Warren Alpert Medical School of Brown University, RI, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kenu</LastName><ForeName>Ernest</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Medicine, Korle Bu Teaching Hospital, Korle-Bu Accra.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gillani</LastName><ForeName>Fizza Syeda</ForeName><Initials>FS</Initials><AffiliationInfo><Affiliation>Warren Alpert Medical School of Brown University, RI, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Miriam Hospital, Providence, RI, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Obo-Akwa</LastName><ForeName>Adjoa</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Ghana School of Medicine & Dentistry, College of Health Sciences, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lartey</LastName><ForeName>Margaret</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Medicine, Korle Bu Teaching Hospital, Korle-Bu Accra.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medicine, University of Ghana School of Medicine & Dentistry, College of Health Sciences, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kwara</LastName><ForeName>Awewura</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Brown University, Providence, RI, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Warren Alpert Medical School of Brown University, RI, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Miriam Hospital, Providence, RI, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Florida College of Medicine, Gainesville, FL, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>05</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>Uganda</Country><MedlineTA>Pan Afr Med J</MedlineTA><NlmUniqueID>101517926</NlmUniqueID></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D019380">Anti-HIV Agents</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Lancet. 1998 Nov 28;352(9142):1725-30</RefSource><PMID Version="1">9848347</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Afr J Prim Health Care Fam Med. 2015;7(1):doi: 10.4102/phcfm.v7i1.883</RefSource><PMID Version="1">26466398</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2013 Aug 16;8(8):e72202</RefSource><PMID Version="1">23977253</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Infect Dev Ctries. 2011 May 28;5(5):377-82</RefSource><PMID Version="1">21628815</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ghana Med J. 2015 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Version="1">17932435</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Infect Dis. 2013 Oct;13(10):852-8</RefSource><PMID Version="1">23954450</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Hematology Am Soc Hematol Educ Program. 2013;2013:377-81</RefSource><PMID Version="1">24319207</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D017088" MajorTopicYN="N">AIDS-Related Opportunistic Infections</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019380" MajorTopicYN="N">Anti-HIV Agents</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D023241" MajorTopicYN="N">Antiretroviral Therapy, Highly Active</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002423" MajorTopicYN="Y">Cause of Death</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005869" MajorTopicYN="N">Ghana</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015658" MajorTopicYN="N">HIV Infections</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017052" MajorTopicYN="Y">Hospital Mortality</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006784" MajorTopicYN="N">Hospitals, Teaching</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Cause of Death</Keyword><Keyword MajorTopicYN="N">Ghana</Keyword><Keyword MajorTopicYN="N">HAART</Keyword><Keyword MajorTopicYN="N">HIV/AIDS</Keyword><Keyword MajorTopicYN="N">Tuberculosis</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>01</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>04</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>8</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>8</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28819470</ArticleId><ArticleId IdType="doi">10.11604/pamj.2017.27.48.8917</ArticleId><ArticleId IdType="pii">PAMJ-27-48</ArticleId><ArticleId IdType="pmc">PMC5554638</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Ghana</li><li>États-Unis</li></country><region><li>Rhode Island</li><li>Région du Grand Accra</li></region><settlement><li>Accra</li><li>Legon (Ghana)</li><li>Providence (Rhode Island)</li></settlement><orgName><li>Université Brown</li><li>Université du Ghana</li></orgName></list><tree><noCountry><name sortKey="Kenu, Ernest" sort="Kenu, Ernest" uniqKey="Kenu E" first="Ernest" last="Kenu">Ernest Kenu</name></noCountry><country name="États-Unis"><region name="Rhode Island"><name sortKey="Saavedra, Adriana" sort="Saavedra, Adriana" uniqKey="Saavedra A" first="Adriana" last="Saavedra">Adriana Saavedra</name></region><name sortKey="Campinha Bacote, Nia" sort="Campinha Bacote, Nia" uniqKey="Campinha Bacote N" first="Nia" last="Campinha-Bacote">Nia Campinha-Bacote</name><name sortKey="Gillani, Fizza Syeda" sort="Gillani, Fizza Syeda" uniqKey="Gillani F" first="Fizza Syeda" last="Gillani">Fizza Syeda Gillani</name><name sortKey="Hajjar, Maurice" sort="Hajjar, Maurice" uniqKey="Hajjar M" first="Maurice" last="Hajjar">Maurice Hajjar</name><name sortKey="Kwara, Awewura" sort="Kwara, Awewura" uniqKey="Kwara A" first="Awewura" last="Kwara">Awewura Kwara</name></country><country name="Ghana"><region name="Région du Grand Accra"><name sortKey="Obo Akwa, Adjoa" sort="Obo Akwa, Adjoa" uniqKey="Obo Akwa A" first="Adjoa" last="Obo-Akwa">Adjoa Obo-Akwa</name></region><name sortKey="Lartey, Margaret" sort="Lartey, Margaret" uniqKey="Lartey M" first="Margaret" last="Lartey">Margaret Lartey</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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