Human herpesvirus 8 transfusion transmission in Ghana, an endemic region of West Africa
Identifieur interne : 000338 ( Istex/Curation ); précédent : 000337; suivant : 000339Human herpesvirus 8 transfusion transmission in Ghana, an endemic region of West Africa
Auteurs : Francesca Gobbini [Royaume-Uni] ; Shirley Owusu-Ofori [Royaume-Uni] ; Anne-Geneviève Marcelin [Royaume-Uni] ; Daniel Candotti [Royaume-Uni] ; Jean-Pierre Allain [Royaume-Uni]Source :
- Transfusion [ 0041-1132 ] ; 2012-11.
Descripteurs français
- Wicri :
- geographic : Ghana.
- topic : Transfusion sanguine.
English descriptors
- KwdEn :
- Assay, Blood donors, Blood products, Blood recipients, Blood samples, Blood transfusion, Bootstrap value, Cambridge blood centre, Cellular fraction, Donor, Genotype, Ghana, Ghanaian, Ghanaian samples, Ghanaian sequences, Guinean samples, Herpesvirus, High titer, Human herpesvirus, Human herpesvirus type, Immune response, Immunocompetent recipients, Immunosuppressive drugs, Komfo anokye teaching hospital, Minor capsid protein, Posttransfusion, Posttransfusion sample, Posttransfusion samples, Serologic, Seronegative, Seronegative recipients, Seropositive, Seropositive blood, Seroprevalence, Transfusion, Transfusion transmission, Transfusion volume, Viral load, West africa, Whole blood.
- Teeft :
- Assay, Blood donors, Blood products, Blood recipients, Blood samples, Blood transfusion, Bootstrap value, Cambridge blood centre, Cellular fraction, Donor, Genotype, Ghana, Ghanaian, Ghanaian samples, Ghanaian sequences, Guinean samples, Herpesvirus, High titer, Human herpesvirus, Human herpesvirus type, Immune response, Immunocompetent recipients, Immunosuppressive drugs, Komfo anokye teaching hospital, Minor capsid protein, Posttransfusion, Posttransfusion sample, Posttransfusion samples, Serologic, Seronegative, Seronegative recipients, Seropositive, Seropositive blood, Seroprevalence, Transfusion, Transfusion transmission, Transfusion volume, Viral load, West africa, Whole blood.
Abstract
BACKGROUND: Human herpesvirus 8 (HHV‐8) seroprevalence ranges between less than 5% in Europe and North America and 50% to 70% in sub‐Saharan Africa. Evidence of HHV‐8 transfusion transmission is only indirect. We conducted a serologic (anti‐HHV‐8) and molecular (HHV‐8 DNA) study of samples from paired donor‐immunocompetent recipients transfused with whole blood.
Url:
DOI: 10.1111/j.1537-2995.2012.03607.x
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ISTEX:9E211FE5028F62D309BCDE38024144571E3B5B0ELe document en format XML
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<author><name sortKey="Gobbini, Francesca" sort="Gobbini, Francesca" uniqKey="Gobbini F" first="Francesca" last="Gobbini">Francesca Gobbini</name>
<affiliation wicri:level="1"><mods:affiliation>From the Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK; the Transfusion Medicine Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana; the Virology Laboratory Hospital Pitié‐Salpêtrière, Paris, France; and the National Blood Service, Cambridge Blood Centre, Cambridge, UK.</mods:affiliation>
<country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country>
<wicri:regionArea>From the Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK; the Transfusion Medicine Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana; the Virology Laboratory Hospital Pitié‐Salpêtrière, Paris, France; and the National Blood Service, Cambridge Blood Centre, Cambridge</wicri:regionArea>
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<author><name sortKey="Owusu Fori, Shirley" sort="Owusu Fori, Shirley" uniqKey="Owusu Fori S" first="Shirley" last="Owusu-Ofori">Shirley Owusu-Ofori</name>
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<wicri:regionArea>From the Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK; the Transfusion Medicine Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana; the Virology Laboratory Hospital Pitié‐Salpêtrière, Paris, France; and the National Blood Service, Cambridge Blood Centre, Cambridge</wicri:regionArea>
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<country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country>
<wicri:regionArea>From the Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK; the Transfusion Medicine Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana; the Virology Laboratory Hospital Pitié‐Salpêtrière, Paris, France; and the National Blood Service, Cambridge Blood Centre, Cambridge</wicri:regionArea>
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<country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country>
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<front><div type="abstract">BACKGROUND: Human herpesvirus 8 (HHV‐8) seroprevalence ranges between less than 5% in Europe and North America and 50% to 70% in sub‐Saharan Africa. Evidence of HHV‐8 transfusion transmission is only indirect. We conducted a serologic (anti‐HHV‐8) and molecular (HHV‐8 DNA) study of samples from paired donor‐immunocompetent recipients transfused with whole blood.</div>
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