Sham-Controlled Study of Optokinetic Stimuli as Treatment for Mal de Debarquement Syndrome.
Identifieur interne : 000312 ( Main/Corpus ); précédent : 000311; suivant : 000313Sham-Controlled Study of Optokinetic Stimuli as Treatment for Mal de Debarquement Syndrome.
Auteurs : Viviana Mucci ; Tyché Perkisas ; Steven Douglas Jillings ; Vincent Van Rompaey ; Angelique Van Ombergen ; Erik Fransen ; Luc Vereeck ; Floris L. Wuyts ; Paul H. Van De Heyning ; Cherylea J. BrowneSource :
- Frontiers in neurology [ 1664-2295 ] ; 2018.
Abstract
Introduction: Mal de Debarquement Syndrome (MdDS) is a condition characterized by a perception of self-motion in the absence of a stimulus, with two onset types: Motion-Triggered and Spontaneous. Currently, the pathophysiology is unknown and consequently, the therapeutic options are limited. One proposed treatment protocol, developed by Dai and colleagues is based on optokinetic stimulation, which aims to re-adapt the vestibular ocular reflex. This study aimed to reproduce the treatment protocol developed by Dai and colleagues and to assess if a placebo effect is present in the treatment protocol and lastly, aimed to further investigate the treatment on MdDS patient outcomes. Method: Twenty-five MdDS patients (13 Motion-Triggered and 12 Spontaneous) were exposed to 5 consecutive days of optokinetic treatment (consisting of exposure to optokinetic stimuli with head movements). Eleven of these 25 patients were also exposed to 2 days of a sham treatment prior to the OKN treatment. Posturography measurements and reported symptoms [e.g., using the visual analog scale (VAS)] of patients were assessed throughout the treatment. Posturography data of the patients was compared with the data of 20 healthy controls. Results: No placebo effect was recorded with any changes in postural data and VAS scale. After the optokinetic treatment, a significant improvement in postural control was observed in 48% of patients, of whom 70% were of the Motion-Triggered subtype (p-values: Area under the Curve-Anterior Posterior < 0.001; Area under the Curve-Medio Lateral p < 0.001, Confidence Ellipse Area (CEA) < 0.001, Velocity < 0.001). Conclusion: The protocol was effective in approximately half of the MdDS patients that took part in the study, with no placebo effect recorded. The Motion-Triggered group responded better to treatment than the Spontaneous group. In addition to this, this study indicates that the greatest postural changes occur within the first 3 days of treatment, suggesting that a shorter protocol is possible. Overall, these findings support what was previously observed in Dai's studies, that optokinetic stimulation can reduce and ease self-motion perception in those with MdDS. Thus, validating the reproducibility of this protocol, suggesting that a consistent and uncomplicated implementation across treatment centers is possible.
DOI: 10.3389/fneur.2018.00887
PubMed: 30410464
PubMed Central: PMC6210740
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pubmed:30410464Le document en format XML
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<author><name sortKey="Fransen, Erik" sort="Fransen, Erik" uniqKey="Fransen E" first="Erik" last="Fransen">Erik Fransen</name>
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<author><name sortKey="Vereeck, Luc" sort="Vereeck, Luc" uniqKey="Vereeck L" first="Luc" last="Vereeck">Luc Vereeck</name>
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<affiliation><nlm:affiliation>Multidisciplinary Motor Centre Antwerp (M2OCEAN), University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
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<author><name sortKey="Wuyts, Floris L" sort="Wuyts, Floris L" uniqKey="Wuyts F" first="Floris L" last="Wuyts">Floris L. Wuyts</name>
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<author><name sortKey="Van De Heyning, Paul H" sort="Van De Heyning, Paul H" uniqKey="Van De Heyning P" first="Paul H" last="Van De Heyning">Paul H. Van De Heyning</name>
<affiliation><nlm:affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.</nlm:affiliation>
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<affiliation><nlm:affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
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<affiliation><nlm:affiliation>Multidisciplinary Motor Centre Antwerp (M2OCEAN), University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
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<author><name sortKey="Browne, Cherylea J" sort="Browne, Cherylea J" uniqKey="Browne C" first="Cherylea J" last="Browne">Cherylea J. Browne</name>
<affiliation><nlm:affiliation>School of Science and Health, Western Sydney University, Sydney, NSW, Australia.</nlm:affiliation>
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<affiliation><nlm:affiliation>Translational Neuroscience Facility, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Sham-Controlled Study of Optokinetic Stimuli as Treatment for Mal de Debarquement Syndrome.</title>
<author><name sortKey="Mucci, Viviana" sort="Mucci, Viviana" uniqKey="Mucci V" first="Viviana" last="Mucci">Viviana Mucci</name>
<affiliation><nlm:affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Perkisas, Tyche" sort="Perkisas, Tyche" uniqKey="Perkisas T" first="Tyché" last="Perkisas">Tyché Perkisas</name>
<affiliation><nlm:affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
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<author><name sortKey="Jillings, Steven Douglas" sort="Jillings, Steven Douglas" uniqKey="Jillings S" first="Steven Douglas" last="Jillings">Steven Douglas Jillings</name>
<affiliation><nlm:affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Rompaey, Vincent" sort="Van Rompaey, Vincent" uniqKey="Van Rompaey V" first="Vincent" last="Van Rompaey">Vincent Van Rompaey</name>
<affiliation><nlm:affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Ombergen, Angelique" sort="Van Ombergen, Angelique" uniqKey="Van Ombergen A" first="Angelique" last="Van Ombergen">Angelique Van Ombergen</name>
<affiliation><nlm:affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Fransen, Erik" sort="Fransen, Erik" uniqKey="Fransen E" first="Erik" last="Fransen">Erik Fransen</name>
<affiliation><nlm:affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
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<author><name sortKey="Vereeck, Luc" sort="Vereeck, Luc" uniqKey="Vereeck L" first="Luc" last="Vereeck">Luc Vereeck</name>
<affiliation><nlm:affiliation>Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Science, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
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<affiliation><nlm:affiliation>Multidisciplinary Motor Centre Antwerp (M2OCEAN), University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Wuyts, Floris L" sort="Wuyts, Floris L" uniqKey="Wuyts F" first="Floris L" last="Wuyts">Floris L. Wuyts</name>
<affiliation><nlm:affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Van De Heyning, Paul H" sort="Van De Heyning, Paul H" uniqKey="Van De Heyning P" first="Paul H" last="Van De Heyning">Paul H. Van De Heyning</name>
<affiliation><nlm:affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Multidisciplinary Motor Centre Antwerp (M2OCEAN), University of Antwerp, Antwerp, Belgium.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Browne, Cherylea J" sort="Browne, Cherylea J" uniqKey="Browne C" first="Cherylea J" last="Browne">Cherylea J. Browne</name>
<affiliation><nlm:affiliation>School of Science and Health, Western Sydney University, Sydney, NSW, Australia.</nlm:affiliation>
</affiliation>
<affiliation><nlm:affiliation>Translational Neuroscience Facility, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
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<front><div type="abstract" xml:lang="en"><b>Introduction:</b>
Mal de Debarquement Syndrome (MdDS) is a condition characterized by a perception of self-motion in the absence of a stimulus, with two onset types: Motion-Triggered and Spontaneous. Currently, the pathophysiology is unknown and consequently, the therapeutic options are limited. One proposed treatment protocol, developed by Dai and colleagues is based on optokinetic stimulation, which aims to re-adapt the vestibular ocular reflex. This study aimed to reproduce the treatment protocol developed by Dai and colleagues and to assess if a placebo effect is present in the treatment protocol and lastly, aimed to further investigate the treatment on MdDS patient outcomes. <b>Method:</b>
Twenty-five MdDS patients (13 Motion-Triggered and 12 Spontaneous) were exposed to 5 consecutive days of optokinetic treatment (consisting of exposure to optokinetic stimuli with head movements). Eleven of these 25 patients were also exposed to 2 days of a sham treatment prior to the OKN treatment. Posturography measurements and reported symptoms [e.g., using the visual analog scale (VAS)] of patients were assessed throughout the treatment. Posturography data of the patients was compared with the data of 20 healthy controls. <b>Results:</b>
No placebo effect was recorded with any changes in postural data and VAS scale. After the optokinetic treatment, a significant improvement in postural control was observed in 48% of patients, of whom 70% were of the Motion-Triggered subtype (<i>p</i>
-values: Area under the Curve-Anterior Posterior < 0.001; Area under the Curve-Medio Lateral <i>p</i>
< 0.001, Confidence Ellipse Area (CEA) < 0.001, Velocity < 0.001). <b>Conclusion:</b>
The protocol was effective in approximately half of the MdDS patients that took part in the study, with no placebo effect recorded. The Motion-Triggered group responded better to treatment than the Spontaneous group. In addition to this, this study indicates that the greatest postural changes occur within the first 3 days of treatment, suggesting that a shorter protocol is possible. Overall, these findings support what was previously observed in Dai's studies, that optokinetic stimulation can reduce and ease self-motion perception in those with MdDS. Thus, validating the reproducibility of this protocol, suggesting that a consistent and uncomplicated implementation across treatment centers is possible.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">30410464</PMID>
<DateRevised><Year>2020</Year>
<Month>09</Month>
<Day>30</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Print">1664-2295</ISSN>
<JournalIssue CitedMedium="Print"><Volume>9</Volume>
<PubDate><Year>2018</Year>
</PubDate>
</JournalIssue>
<Title>Frontiers in neurology</Title>
<ISOAbbreviation>Front Neurol</ISOAbbreviation>
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<ArticleTitle>Sham-Controlled Study of Optokinetic Stimuli as Treatment for Mal de Debarquement Syndrome.</ArticleTitle>
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<ELocationID EIdType="doi" ValidYN="Y">10.3389/fneur.2018.00887</ELocationID>
<Abstract><AbstractText><b>Introduction:</b>
Mal de Debarquement Syndrome (MdDS) is a condition characterized by a perception of self-motion in the absence of a stimulus, with two onset types: Motion-Triggered and Spontaneous. Currently, the pathophysiology is unknown and consequently, the therapeutic options are limited. One proposed treatment protocol, developed by Dai and colleagues is based on optokinetic stimulation, which aims to re-adapt the vestibular ocular reflex. This study aimed to reproduce the treatment protocol developed by Dai and colleagues and to assess if a placebo effect is present in the treatment protocol and lastly, aimed to further investigate the treatment on MdDS patient outcomes. <b>Method:</b>
Twenty-five MdDS patients (13 Motion-Triggered and 12 Spontaneous) were exposed to 5 consecutive days of optokinetic treatment (consisting of exposure to optokinetic stimuli with head movements). Eleven of these 25 patients were also exposed to 2 days of a sham treatment prior to the OKN treatment. Posturography measurements and reported symptoms [e.g., using the visual analog scale (VAS)] of patients were assessed throughout the treatment. Posturography data of the patients was compared with the data of 20 healthy controls. <b>Results:</b>
No placebo effect was recorded with any changes in postural data and VAS scale. After the optokinetic treatment, a significant improvement in postural control was observed in 48% of patients, of whom 70% were of the Motion-Triggered subtype (<i>p</i>
-values: Area under the Curve-Anterior Posterior < 0.001; Area under the Curve-Medio Lateral <i>p</i>
< 0.001, Confidence Ellipse Area (CEA) < 0.001, Velocity < 0.001). <b>Conclusion:</b>
The protocol was effective in approximately half of the MdDS patients that took part in the study, with no placebo effect recorded. The Motion-Triggered group responded better to treatment than the Spontaneous group. In addition to this, this study indicates that the greatest postural changes occur within the first 3 days of treatment, suggesting that a shorter protocol is possible. Overall, these findings support what was previously observed in Dai's studies, that optokinetic stimulation can reduce and ease self-motion perception in those with MdDS. Thus, validating the reproducibility of this protocol, suggesting that a consistent and uncomplicated implementation across treatment centers is possible.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mucci</LastName>
<ForeName>Viviana</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Perkisas</LastName>
<ForeName>Tyché</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jillings</LastName>
<ForeName>Steven Douglas</ForeName>
<Initials>SD</Initials>
<AffiliationInfo><Affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Van Rompaey</LastName>
<ForeName>Vincent</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Van Ombergen</LastName>
<ForeName>Angelique</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fransen</LastName>
<ForeName>Erik</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vereeck</LastName>
<ForeName>Luc</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Science, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Multidisciplinary Motor Centre Antwerp (M2OCEAN), University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wuyts</LastName>
<ForeName>Floris L</ForeName>
<Initials>FL</Initials>
<AffiliationInfo><Affiliation>Departments of Biomedical Physics, Faculty of Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Van de Heyning</LastName>
<ForeName>Paul H</ForeName>
<Initials>PH</Initials>
<AffiliationInfo><Affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Multidisciplinary Motor Centre Antwerp (M2OCEAN), University of Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Browne</LastName>
<ForeName>Cherylea J</ForeName>
<Initials>CJ</Initials>
<AffiliationInfo><Affiliation>School of Science and Health, Western Sydney University, Sydney, NSW, Australia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Translational Neuroscience Facility, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>10</Month>
<Day>25</Day>
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<MedlineJournalInfo><Country>Switzerland</Country>
<MedlineTA>Front Neurol</MedlineTA>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Mal de debarquement syndrome</Keyword>
<Keyword MajorTopicYN="N">MdDS</Keyword>
<Keyword MajorTopicYN="N">optokinetic stimulation</Keyword>
<Keyword MajorTopicYN="N">placebo</Keyword>
<Keyword MajorTopicYN="N">spontaneous and motion triggered MdDS</Keyword>
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<ReferenceList><Reference><Citation>Vision Res. 1997 Jun;37(12):1643-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9231230</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Ann N Y Acad Sci. 2015 Apr;1343:63-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25726862</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biomed Sci Instrum. 2012;48:332-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22846302</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Neurol. 2016 May;263(5):843-854</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26559820</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Neurophysiol. 1991 Oct;66(4):1422-39</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1761991</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Neurol. 2018 Feb 12;9:42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29483889</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Neurol. 2016 May;263(5):855-860</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27067708</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Gait Posture. 2010 Mar;31(3):307-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20005112</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Otol Neurotol. 2016 Jul;37(6):805-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27176615</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Neurol. 2018 May 07;9:261</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29867709</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Otolaryngol Head Neck Surg. 1999 Jun;125(6):615-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10367916</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Appl Physiol. 1962 May;17:398-404</Citation>
<ArticleIdList><ArticleId IdType="pubmed">13902616</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Neurol. 2018 Feb 05;9:28</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29459843</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Laryngoscope. 2017 Jul;127(7):1670-1675</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27730651</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Neurol. 2012 Jul;259(7):1326-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22231864</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Neurol. 2008 Jul;255(7):1038-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18500497</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Neurol. 2016 May 20;16:70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27206921</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Neurol. 2018 Mar;265(3):486-499</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29305644</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Neurol. 2017 May 05;8:175</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28529496</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Aviat Space Environ Med. 2005 Dec;76(12):1111-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16370260</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Otolaryngol. 1987 Jul-Aug;8(4):219-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3631419</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Exp Brain Res. 1991;87(1):57-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1756833</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Handb Clin Neurol. 2016;137:391-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27638086</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Acoust Soc Am. 1987 Sep;82(3):957-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3655126</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biomed Res Int. 2015;2015:891390</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26640800</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cephalalgia. 2013 Oct;33(14):1160-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23674832</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO Rep. 2012 Apr 02;13(4):291-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22421999</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Neurosci. 2013 Mar;20(3):446-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23219828</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Neurol. 2014 Jul 15;5:124</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25076935</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2016 Apr 29;11(4):e0154528</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27128970</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Otolaryngol Head Neck Surg. 1995 Jan;112(1):8-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7816461</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Womens Health Issues. 2008 Jul-Aug;18(4):328-35</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18485739</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Exp Brain Res. 1981;41(2):159-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6970678</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Neurology. 2014 Sep 30;83(14):1241-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25165387</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Semin Neurol. 2009 Nov;29(5):520-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19834863</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biomech. 2013 Apr 26;46(7):1392-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23528845</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>
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