Neurodegenerative disorders: Parkinson’s disease and Huntington’s disease
Identifieur interne : 001460 ( Main/Exploration ); précédent : 001459; suivant : 001461Neurodegenerative disorders: Parkinson’s disease and Huntington’s disease
Auteurs : S M Hague [Royaume-Uni] ; S. Klaffke [Royaume-Uni] ; O. Bandmann [Royaume-Uni]Source :
- Journal of Neurology, Neurosurgery & Psychiatry [ 0022-3050 ] ; 2005-08.
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Abstract
Parkinson’s disease and Huntington’s disease are both model diseases. Parkinson’s disease is the most common of several akinetic-rigid syndromes and Huntington’s disease is only one of an ever growing number of trinucleotide repeat disorders. Molecular genetic studies and subsequent molecular biological studies have provided fascinating new insights into the pathogenesis of both disorders and there is now real hope for disease modifying treatment in the not too distant future for patients with Parkinson’s disease or Huntington’s disease.
Url:
DOI: 10.1136/jnnp.2004.060186
Affiliations:
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<term>Huntington’s disease</term>
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<front><div type="abstract" xml:lang="en">Parkinson’s disease and Huntington’s disease are both model diseases. Parkinson’s disease is the most common of several akinetic-rigid syndromes and Huntington’s disease is only one of an ever growing number of trinucleotide repeat disorders. Molecular genetic studies and subsequent molecular biological studies have provided fascinating new insights into the pathogenesis of both disorders and there is now real hope for disease modifying treatment in the not too distant future for patients with Parkinson’s disease or Huntington’s disease.</div>
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