MRI-Stereotactical Approach for Neural Grafting in Basal Ganglia Disorders
Identifieur interne : 002C07 ( Main/Curation ); précédent : 002C06; suivant : 002C08MRI-Stereotactical Approach for Neural Grafting in Basal Ganglia Disorders
Auteurs : S. Palfi [France] ; J. P. Nguyen [France] ; P. Brugieres [France] ; C. Le Guerinel [France] ; P. Hantraye [France] ; P. Remy [France] ; S. Rostaing [France] ; G. L. Defer [France] ; P. Cesaro [France] ; Y. Keravel [France] ; M. Peschanski [France]Source :
- Experimental Neurology [ 0014-4886 ] ; 1997.
English descriptors
- KwdEn :
Abstract
Optimization of the procedures for neural grafting is a timely issue, as this technique has proven beneficial for a few patients with late-stage Parkinson's disease in pilot studies and therefore may expand to become a more widely available therapeutic. In this research, one major issue is that of the placement of the cell deposits in the right target areas within the striatum. Although it is widely accepted that these suitable regions are the sensorimotor regions of the putamen, reliable delineation of these areas using classical stereotactical mapping techniques remains difficult. Along the course of a 5-year-long clinical transplantation program, we have developed an original procedure based on magnetic resonance imaging of the striatum on parasagittal views. This technique allowed us to identify precisely, and reproducibly in each patient, three subregions of the putamen (precommissural, commissural, and postcommissural) to be implanted. On the basis of the literature defining the sensorimotor putaminal regions in nonhuman primates, it was subsequently possible to extrapolate and localize these regions in each patient, thus providing a basis for the placement of cell deposits. Examples taken from our series of grafted patients demonstrate the value of this procedure that, in addition, minimizes interference of interindividual variability in the interpretation of clinical results.
Url:
DOI: 10.1006/exnr.1997.6754
Links toward previous steps (curation, corpus...)
- to stream Main, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002F98
Links to Exploration step
ISTEX:9105FA6589BDD47225A65820FD0A4BB2D827BC54Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">MRI-Stereotactical Approach for Neural Grafting in Basal Ganglia Disorders</title>
<author><name sortKey="Palfi, S" sort="Palfi, S" uniqKey="Palfi S" first="S." last="Palfi">S. Palfi</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nguyen, J P" sort="Nguyen, J P" uniqKey="Nguyen J" first="J. P." last="Nguyen">J. P. Nguyen</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brugieres, P" sort="Brugieres, P" uniqKey="Brugieres P" first="P." last="Brugieres">P. Brugieres</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neuroradiologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neuroradiologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Le Guerinel, C" sort="Le Guerinel, C" uniqKey="Le Guerinel C" first="C." last="Le Guerinel">C. Le Guerinel</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hantraye, P" sort="Hantraye, P" uniqKey="Hantraye P" first="P." last="Hantraye">P. Hantraye</name>
<affiliation wicri:level="1"><mods:affiliation>CEA CNRS URA 2210, Service Hospitalier Frédéric Joliot, CEA, DSV, DRIPP, 4 place du Général Leclerc, 91401, Orsay Cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CEA CNRS URA 2210, Service Hospitalier Frédéric Joliot, CEA, DSV, DRIPP, 4 place du Général Leclerc, 91401, Orsay Cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Remy, P" sort="Remy, P" uniqKey="Remy P" first="P." last="Remy">P. Remy</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rostaing, S" sort="Rostaing, S" uniqKey="Rostaing S" first="S." last="Rostaing">S. Rostaing</name>
<affiliation wicri:level="1"><mods:affiliation>Service d'Anesthésie Réanimation, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service d'Anesthésie Réanimation, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Defer, G L" sort="Defer, G L" uniqKey="Defer G" first="G. L." last="Defer">G. L. Defer</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurologie Déjerine, CHU Côte de Nâcre, 14000, Caen, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie Déjerine, CHU Côte de Nâcre, 14000, Caen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cesaro, P" sort="Cesaro, P" uniqKey="Cesaro P" first="P." last="Cesaro">P. Cesaro</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Keravel, Y" sort="Keravel, Y" uniqKey="Keravel Y" first="Y." last="Keravel">Y. Keravel</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peschanski, M" sort="Peschanski, M" uniqKey="Peschanski M" first="M." last="Peschanski">M. Peschanski</name>
<affiliation wicri:level="1"><mods:affiliation>Inserm U 421, IM3, Faculté de médecine, 8 rue du Général Sarrail, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm U 421, IM3, Faculté de médecine, 8 rue du Général Sarrail, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:9105FA6589BDD47225A65820FD0A4BB2D827BC54</idno>
<date when="1998" year="1998">1998</date>
<idno type="doi">10.1006/exnr.1997.6754</idno>
<idno type="url">https://api.istex.fr/document/9105FA6589BDD47225A65820FD0A4BB2D827BC54/fulltext/pdf</idno>
<idno type="wicri:Area/Main/Corpus">002F98</idno>
<idno type="wicri:Area/Main/Curation">002C07</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">MRI-Stereotactical Approach for Neural Grafting in Basal Ganglia Disorders</title>
<author><name sortKey="Palfi, S" sort="Palfi, S" uniqKey="Palfi S" first="S." last="Palfi">S. Palfi</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nguyen, J P" sort="Nguyen, J P" uniqKey="Nguyen J" first="J. P." last="Nguyen">J. P. Nguyen</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brugieres, P" sort="Brugieres, P" uniqKey="Brugieres P" first="P." last="Brugieres">P. Brugieres</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neuroradiologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neuroradiologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Le Guerinel, C" sort="Le Guerinel, C" uniqKey="Le Guerinel C" first="C." last="Le Guerinel">C. Le Guerinel</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hantraye, P" sort="Hantraye, P" uniqKey="Hantraye P" first="P." last="Hantraye">P. Hantraye</name>
<affiliation wicri:level="1"><mods:affiliation>CEA CNRS URA 2210, Service Hospitalier Frédéric Joliot, CEA, DSV, DRIPP, 4 place du Général Leclerc, 91401, Orsay Cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CEA CNRS URA 2210, Service Hospitalier Frédéric Joliot, CEA, DSV, DRIPP, 4 place du Général Leclerc, 91401, Orsay Cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Remy, P" sort="Remy, P" uniqKey="Remy P" first="P." last="Remy">P. Remy</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rostaing, S" sort="Rostaing, S" uniqKey="Rostaing S" first="S." last="Rostaing">S. Rostaing</name>
<affiliation wicri:level="1"><mods:affiliation>Service d'Anesthésie Réanimation, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service d'Anesthésie Réanimation, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Defer, G L" sort="Defer, G L" uniqKey="Defer G" first="G. L." last="Defer">G. L. Defer</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurologie Déjerine, CHU Côte de Nâcre, 14000, Caen, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie Déjerine, CHU Côte de Nâcre, 14000, Caen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cesaro, P" sort="Cesaro, P" uniqKey="Cesaro P" first="P." last="Cesaro">P. Cesaro</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Keravel, Y" sort="Keravel, Y" uniqKey="Keravel Y" first="Y." last="Keravel">Y. Keravel</name>
<affiliation wicri:level="1"><mods:affiliation>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurochirurgie, Hôpital Henri Mondor, 55 Avenue du Maréchal De Lattre de Tassigny, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peschanski, M" sort="Peschanski, M" uniqKey="Peschanski M" first="M." last="Peschanski">M. Peschanski</name>
<affiliation wicri:level="1"><mods:affiliation>Inserm U 421, IM3, Faculté de médecine, 8 rue du Général Sarrail, 94010, Créteil, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm U 421, IM3, Faculté de médecine, 8 rue du Général Sarrail, 94010, Créteil</wicri:regionArea>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Experimental Neurology</title>
<title level="j" type="abbrev">YEXNR</title>
<idno type="ISSN">0014-4886</idno>
<imprint><publisher>ELSEVIER</publisher>
<date type="published" when="1997">1997</date>
<biblScope unit="volume">150</biblScope>
<biblScope unit="issue">2</biblScope>
<biblScope unit="page" from="272">272</biblScope>
<biblScope unit="page" to="281">281</biblScope>
</imprint>
<idno type="ISSN">0014-4886</idno>
</series>
<idno type="istex">9105FA6589BDD47225A65820FD0A4BB2D827BC54</idno>
<idno type="DOI">10.1006/exnr.1997.6754</idno>
<idno type="PII">S0014-4886(97)96754-6</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0014-4886</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson disease</term>
<term>fetal mesencephalic tissue.</term>
<term>grafting</term>
<term>magnetic resonance imaging</term>
<term>stereotaxy</term>
<term>striatum</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Optimization of the procedures for neural grafting is a timely issue, as this technique has proven beneficial for a few patients with late-stage Parkinson's disease in pilot studies and therefore may expand to become a more widely available therapeutic. In this research, one major issue is that of the placement of the cell deposits in the right target areas within the striatum. Although it is widely accepted that these suitable regions are the sensorimotor regions of the putamen, reliable delineation of these areas using classical stereotactical mapping techniques remains difficult. Along the course of a 5-year-long clinical transplantation program, we have developed an original procedure based on magnetic resonance imaging of the striatum on parasagittal views. This technique allowed us to identify precisely, and reproducibly in each patient, three subregions of the putamen (precommissural, commissural, and postcommissural) to be implanted. On the basis of the literature defining the sensorimotor putaminal regions in nonhuman primates, it was subsequently possible to extrapolate and localize these regions in each patient, thus providing a basis for the placement of cell deposits. Examples taken from our series of grafted patients demonstrate the value of this procedure that, in addition, minimizes interference of interindividual variability in the interpretation of clinical results.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002C07 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 002C07 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonV1 |flux= Main |étape= Curation |type= RBID |clé= ISTEX:9105FA6589BDD47225A65820FD0A4BB2D827BC54 |texte= MRI-Stereotactical Approach for Neural Grafting in Basal Ganglia Disorders }}
This area was generated with Dilib version V0.6.23. |