Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases
Identifieur interne : 002B76 ( Main/Corpus ); précédent : 002B75; suivant : 002B77Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases
Auteurs : C. Wikkels ; C. BlomstrandSource :
- Acta Neurologica Scandinavica [ 0001-6314 ] ; 1982-08.
English descriptors
Abstract
Cerebrospinal fluid (CSF) from patients suffering from various degenerative neurological diseases was fractionated into “CSF‐specific” and antigenically serum‐like proteins, using affinity chromatography with antihuman serum antibodies. The samples were isoelectric focused. Protein patterns were compared to similarly treated CSF from young normal volunteers and age matched controls. Several changes are described and 2 pathological patterns of the CSF‐specific fraction could be identified. One pattern was characteristic for Alzheimer's dementia (AD) and senile dementia of the Alzheimer type (SDAT), but also seen in a few other diseases. The other pattern was seen in several of the investigated groups, most prominent in Huntington's chorea.
Url:
DOI: 10.1111/j.1600-0404.1982.tb04517.x
Links to Exploration step
ISTEX:E438BB23FE5A99562519E7DA791E66BDFA27F6BFLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases</title><author><name sortKey="Wikkels, C" sort="Wikkels, C" uniqKey="Wikkels C" first="C." last="Wikkels">C. Wikkels</name><affiliation><mods:affiliation>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</mods:affiliation></affiliation></author><author><name sortKey="Blomstrand, C" sort="Blomstrand, C" uniqKey="Blomstrand C" first="C." last="Blomstrand">C. Blomstrand</name><affiliation><mods:affiliation>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:E438BB23FE5A99562519E7DA791E66BDFA27F6BF</idno><date when="1982" year="1982">1982</date><idno type="doi">10.1111/j.1600-0404.1982.tb04517.x</idno><idno type="url">https://api.istex.fr/document/E438BB23FE5A99562519E7DA791E66BDFA27F6BF/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">002B76</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases</title><author><name sortKey="Wikkels, C" sort="Wikkels, C" uniqKey="Wikkels C" first="C." last="Wikkels">C. Wikkels</name><affiliation><mods:affiliation>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</mods:affiliation></affiliation></author><author><name sortKey="Blomstrand, C" sort="Blomstrand, C" uniqKey="Blomstrand C" first="C." last="Blomstrand">C. Blomstrand</name><affiliation><mods:affiliation>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Acta Neurologica Scandinavica</title><idno type="ISSN">0001-6314</idno><idno type="eISSN">1600-0404</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1982-08">1982-08</date><biblScope unit="volume">66</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="199">199</biblScope><biblScope unit="page" to="208">208</biblScope></imprint><idno type="ISSN">0001-6314</idno></series><idno type="istex">E438BB23FE5A99562519E7DA791E66BDFA27F6BF</idno><idno type="DOI">10.1111/j.1600-0404.1982.tb04517.x</idno><idno type="ArticleID">ANE199</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0001-6314</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>degenerative neurological diseases</term><term>“CSF‐specific” proteins</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Cerebrospinal fluid (CSF) from patients suffering from various degenerative neurological diseases was fractionated into “CSF‐specific” and antigenically serum‐like proteins, using affinity chromatography with antihuman serum antibodies. The samples were isoelectric focused. Protein patterns were compared to similarly treated CSF from young normal volunteers and age matched controls. Several changes are described and 2 pathological patterns of the CSF‐specific fraction could be identified. One pattern was characteristic for Alzheimer's dementia (AD) and senile dementia of the Alzheimer type (SDAT), but also seen in a few other diseases. The other pattern was seen in several of the investigated groups, most prominent in Huntington's chorea.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>C. Wikkelsø</name><affiliations><json:string>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</json:string></affiliations></json:item><json:item><name>C. Blomstrand</name><affiliations><json:string>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>“CSF‐specific” proteins</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>degenerative neurological diseases</value></json:item></subject><articleId><json:string>ANE199</json:string></articleId><language><json:string>eng</json:string></language><abstract>Cerebrospinal fluid (CSF) from patients suffering from various degenerative neurological diseases was fractionated into “CSF‐specific” and antigenically serum‐like proteins, using affinity chromatography with antihuman serum antibodies. The samples were isoelectric focused. Protein patterns were compared to similarly treated CSF from young normal volunteers and age matched controls. Several changes are described and 2 pathological patterns of the CSF‐specific fraction could be identified. One pattern was characteristic for Alzheimer's dementia (AD) and senile dementia of the Alzheimer type (SDAT), but also seen in a few other diseases. The other pattern was seen in several of the investigated groups, most prominent in Huntington's chorea.</abstract><qualityIndicators><score>5.307</score><pdfVersion>1.5</pdfVersion><pdfPageSize>504 x 720 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>2</keywordCount><abstractCharCount>748</abstractCharCount><pdfWordCount>3083</pdfWordCount><pdfCharCount>19296</pdfCharCount><pdfPageCount>10</pdfPageCount><abstractWordCount>102</abstractWordCount></qualityIndicators><title>Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases</title><genre><json:string>article</json:string></genre><host><volume>66</volume><publisherId><json:string>ANE</json:string></publisherId><pages><total>10</total><last>208</last><first>199</first></pages><issn><json:string>0001-6314</json:string></issn><issue>2</issue><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1600-0404</json:string></eissn><title>Acta Neurologica Scandinavica</title><doi><json:string>10.1111/(ISSN)1600-0404</json:string></doi></host><publicationDate>1982</publicationDate><copyrightDate>1982</copyrightDate><doi><json:string>10.1111/j.1600-0404.1982.tb04517.x</json:string></doi><id>E438BB23FE5A99562519E7DA791E66BDFA27F6BF</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/E438BB23FE5A99562519E7DA791E66BDFA27F6BF/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/E438BB23FE5A99562519E7DA791E66BDFA27F6BF/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/E438BB23FE5A99562519E7DA791E66BDFA27F6BF/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><availability><p>WILEY</p></availability><date>1982</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases</title><author><persName><forename type="first">C.</forename><surname>Wikkelsø</surname></persName><note type="correspondence"><p>Correspondence: , M.D. University of Gothenburg Department of Neurology Sahlgren Hospital S‐413 45 Gothenburg Sweden</p></note><affiliation>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</affiliation></author><author><persName><forename type="first">C.</forename><surname>Blomstrand</surname></persName><affiliation>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</affiliation></author></analytic><monogr><title level="j">Acta Neurologica Scandinavica</title><idno type="pISSN">0001-6314</idno><idno type="eISSN">1600-0404</idno><idno type="DOI">10.1111/(ISSN)1600-0404</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1982-08"></date><biblScope unit="volume">66</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="199">199</biblScope><biblScope unit="page" to="208">208</biblScope></imprint></monogr><idno type="istex">E438BB23FE5A99562519E7DA791E66BDFA27F6BF</idno><idno type="DOI">10.1111/j.1600-0404.1982.tb04517.x</idno><idno type="ArticleID">ANE199</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1982</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Cerebrospinal fluid (CSF) from patients suffering from various degenerative neurological diseases was fractionated into “CSF‐specific” and antigenically serum‐like proteins, using affinity chromatography with antihuman serum antibodies. The samples were isoelectric focused. Protein patterns were compared to similarly treated CSF from young normal volunteers and age matched controls. Several changes are described and 2 pathological patterns of the CSF‐specific fraction could be identified. One pattern was characteristic for Alzheimer's dementia (AD) and senile dementia of the Alzheimer type (SDAT), but also seen in a few other diseases. The other pattern was seen in several of the investigated groups, most prominent in Huntington's chorea.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>“CSF‐specific” proteins</term></item><item><term>degenerative neurological diseases</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1982-08">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/E438BB23FE5A99562519E7DA791E66BDFA27F6BF/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1600-0404</doi><issn type="print">0001-6314</issn><issn type="electronic">1600-0404</issn><idGroup><id type="product" value="ANE"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="ACTA NEUROLOGICA SCANDINAVICA">Acta Neurologica Scandinavica</title></titleGroup></publicationMeta><publicationMeta level="part" position="08002"><doi origin="wiley">10.1111/ane.1982.66.issue-2</doi><numberingGroup><numbering type="journalVolume" number="66">66</numbering><numbering type="journalIssue" number="2">2</numbering></numberingGroup><coverDate startDate="1982-08">August 1982</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="0019900" status="forIssue"><doi origin="wiley">10.1111/j.1600-0404.1982.tb04517.x</doi><idGroup><id type="unit" value="ANE199"></id></idGroup><countGroup><count type="pageTotal" number="10"></count></countGroup><copyright>1982 Blackwell Munksgaard</copyright><eventGroup><event type="firstOnline" date="2009-01-29"></event><event type="publishedOnlineFinalForm" date="2009-01-29"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-10"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:4.0.1" date="2014-03-15"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-14"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="199">199</numbering><numbering type="pageLast" number="208">208</numbering></numberingGroup><correspondenceTo><i>C. Wikkelsø</i>, M.D. University of Gothenburg Department of Neurology Sahlgren Hospital S‐413 45 Gothenburg Sweden</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:ANE.ANE199.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>December 22, 1981, January 20, 1982</unparsedEditorialHistory><countGroup><count type="referenceTotal" number="29"></count><count type="linksCrossRef" number="2"></count></countGroup><titleGroup><title type="main">Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1" corresponding="yes"><personName><givenNames>C.</givenNames><familyName>Wikkelsø</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>C.</givenNames><familyName>Blomstrand</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1" countryCode="SE"><unparsedAffiliation>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">“CSF‐specific” proteins</keyword><keyword xml:id="k2">degenerative neurological diseases</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><p>Cerebrospinal fluid (CSF) from patients suffering from various degenerative neurological diseases was fractionated into “CSF‐specific” and antigenically serum‐like proteins, using affinity chromatography with antihuman serum antibodies. The samples were isoelectric focused. Protein patterns were compared to similarly treated CSF from young normal volunteers and age matched controls. Several changes are described and 2 pathological patterns of the CSF‐specific fraction could be identified. One pattern was characteristic for Alzheimer's dementia (AD) and senile dementia of the Alzheimer type (SDAT), but also seen in a few other diseases. The other pattern was seen in several of the investigated groups, most prominent in Huntington's chorea.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases</title></titleInfo><name type="personal"><namePart type="given">C.</namePart><namePart type="family">Wikkelsø</namePart><affiliation>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</affiliation><description>Correspondence: , M.D. University of Gothenburg Department of Neurology Sahlgren Hospital S‐413 45 Gothenburg Sweden</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C.</namePart><namePart type="family">Blomstrand</namePart><affiliation>Department of Neurology, Sahlgren Hospital, University of Gothenburg, Gothenburg, Sweden</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">1982-08</dateIssued><edition>December 22, 1981, January 20, 1982</edition><copyrightDate encoding="w3cdtf">1982</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="references">29</extent></physicalDescription><abstract lang="en">Cerebrospinal fluid (CSF) from patients suffering from various degenerative neurological diseases was fractionated into “CSF‐specific” and antigenically serum‐like proteins, using affinity chromatography with antihuman serum antibodies. The samples were isoelectric focused. Protein patterns were compared to similarly treated CSF from young normal volunteers and age matched controls. Several changes are described and 2 pathological patterns of the CSF‐specific fraction could be identified. One pattern was characteristic for Alzheimer's dementia (AD) and senile dementia of the Alzheimer type (SDAT), but also seen in a few other diseases. The other pattern was seen in several of the investigated groups, most prominent in Huntington's chorea.</abstract><subject lang="en"><genre>Keywords</genre><topic>“CSF‐specific” proteins</topic><topic>degenerative neurological diseases</topic></subject><relatedItem type="host"><titleInfo><title>Acta Neurologica Scandinavica</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">0001-6314</identifier><identifier type="eISSN">1600-0404</identifier><identifier type="DOI">10.1111/(ISSN)1600-0404</identifier><identifier type="PublisherID">ANE</identifier><part><date>1982</date><detail type="volume"><caption>vol.</caption><number>66</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>199</start><end>208</end><total>10</total></extent></part></relatedItem><identifier type="istex">E438BB23FE5A99562519E7DA791E66BDFA27F6BF</identifier><identifier type="DOI">10.1111/j.1600-0404.1982.tb04517.x</identifier><identifier type="ArticleID">ANE199</identifier><accessCondition type="use and reproduction" contentType="copyright">1982 Blackwell Munksgaard</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002B76 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 002B76 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= ISTEX:E438BB23FE5A99562519E7DA791E66BDFA27F6BF
|texte= Cerebrospinal fluid “specific” proteins in various degenerative neurological diseases
}}
| This area was generated with Dilib version V0.6.23. |  |