137 | Humans |
124 | Parkinson Disease |
85 | Male |
67 | Female |
64 | Aged |
59 | Middle Aged |
49 | Animals |
31 | Adult |
28 | Aged, 80 and over |
20 | Mice |
20 | Antiparkinson Agents |
19 | Neurons |
19 | Brain |
18 | Disease Models, Animal |
16 | Levodopa |
15 | Substantia Nigra |
15 | Dopamine |
13 | alpha-Synuclein |
12 | France |
11 | Subthalamic Nucleus |
10 | Risk Factors |
10 | Mutation |
10 | Mice, Inbred C57BL |
10 | Deep Brain Stimulation |
10 | Corpus Striatum |
10 | Case-Control Studies |
9 | Rats |
9 | Nerve Degeneration |
9 | Genetic Predisposition to Disease |
8 | Signal Transduction |
8 | Severity of Illness Index |
8 | Neuropsychological Tests |
8 | Mice, Knockout |
8 | Double-Blind Method |
8 | Basal Ganglia |
7 | tau Proteins |
7 | Psychomotor Performance |
7 | Polymorphism, Single Nucleotide |
7 | Pedigree |
7 | Parkinsonian Disorders |
7 | History, 19th Century |
7 | Genotype |
7 | Europe |
7 | Electric Stimulation Therapy |
7 | Dose-Response Relationship, Drug |
7 | Dopaminergic Neurons |
7 | Dementia |
6 | Young Adult |
6 | Treatment Outcome |
6 | Time Factors |
6 | Neural Pathways |
6 | Mice, Transgenic |
6 | Gene Expression Regulation |
6 | Dyskinesia, Drug-Induced |
6 | Dopamine Agents |
6 | Analysis of Variance |
5 | United States |
5 | Ubiquitin-Protein Ligases |
5 | Parkinson Disease, Secondary |
5 | Oxidopamine |
5 | Nerve Tissue Proteins |
5 | Movement |
5 | Immunohistochemistry |
5 | History, 20th Century |
5 | Depression |
5 | Apoptosis |
5 | Alzheimer Disease |
5 | Age of Onset |
5 | Age Factors |
5 | Adolescent |
5 | Activities of Daily Living |
4 | Tyrosine 3-Monooxygenase |
4 | Surveys and Questionnaires |
4 | Smoking |
4 | Reproducibility of Results |
4 | Reaction Time |
4 | Rats, Sprague-Dawley |
4 | RNA, Messenger |
4 | Pyridines |
4 | Psychiatric Status Rating Scales |
4 | Protein Kinases |
4 | Piperidines |
4 | Phenotype |
4 | Neuroprotective Agents |
4 | Neurodegenerative Diseases |
4 | Mitochondria |
4 | MPTP Poisoning |
4 | Lewy Bodies |
4 | Globus Pallidus |
4 | Genetic Linkage |
4 | Genetic Association Studies |
4 | Frontal Lobe |
4 | Disease Progression |
4 | Cross-Sectional Studies |
4 | Cognition Disorders |
4 | Accidental Falls |
3 | Survival Rate |
3 | Supranuclear Palsy, Progressive |
3 | Sex Distribution |
3 | Receptors, Dopamine D1 |
3 | Randomized Controlled Trials as Topic |
3 | Quality of Life |
3 | Protein-Serine-Threonine Kinases |
3 | Postural Balance |
3 | Point Mutation |
3 | Phosphorylation |
3 | Pedunculopontine Tegmental Nucleus |
3 | Oxidative Stress |
3 | Nerve Net |
3 | Motor Activity |
3 | Molecular Sequence Data |
3 | Mitochondrial Degradation |
3 | Microsatellite Repeats |
3 | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 |
3 | Inflammation |
3 | Indans |
3 | Hypotension, Orthostatic |
3 | Huntington Disease |
3 | Genome-Wide Association Study |
3 | Genetic Variation |
3 | Gene Expression |
3 | Gait |
3 | Follow-Up Studies |
3 | Electrophysiology |
3 | Electrodes, Implanted |
3 | Dyskinesias |
3 | Depressive Disorder |
3 | DNA Mutational Analysis |
3 | Clinical Trials as Topic |
3 | Chromosomes, Human, Pair 17 |
3 | Cells, Cultured |
3 | Cell Death |
3 | Blotting, Western |
3 | Amino Acid Substitution |
3 | Alleles |
3 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
2 | Ventral Tegmental Area |
2 | Ubiquitin Thiolesterase |
2 | Tremor |
2 | Tomography, Emission-Computed |
2 | Tomography, Emission-Computed, Single-Photon |
2 | Thiolester Hydrolases |
2 | Tetrahydronaphthalenes |
2 | Terminology as Topic |
2 | Temporal Lobe |
2 | Syndrome |
2 | Stroke |
2 | Stereotaxic Techniques |
2 | Stereoisomerism |
2 | Statistics, Nonparametric |
2 | Societies, Scientific |
2 | Sex Factors |
2 | Serotonin |
2 | Sequence Homology, Amino Acid |
2 | S100 Calcium Binding Protein G |
2 | Reference Values |
2 | Reference Standards |
2 | REM Sleep Behavior Disorder |
2 | Pyrenes |
2 | Prodrugs |
2 | Prodromal Symptoms |
2 | Prions |
2 | Predictive Value of Tests |
2 | Postoperative Care |
2 | Polymerase Chain Reaction |
2 | Pesticides |
2 | Paris |
2 | Odds Ratio |
2 | Occupational Exposure |
2 | Neurology |
2 | Neurofibrillary Tangles |
2 | Nervous System Diseases |
2 | Neostriatum |
2 | Neoplasms |
2 | Mutation, Missense |
2 | Multicenter Studies as Topic |
2 | Movement Disorders |
2 | Models, Statistical |
2 | Models, Molecular |
2 | Microglia |
2 | Mesencephalon |
2 | Membrane Glycoproteins |
2 | Medical Records |
2 | Markov Chains |
2 | Magnetic Resonance Imaging |
2 | Macaca fascicularis |
2 | Logistic Models |
2 | Lod Score |
2 | Iron |
2 | International Cooperation |
2 | Homeodomain Proteins |
2 | Heterozygote |
2 | Gold |
2 | Germany |
2 | Genetic Loci |
2 | Gene-Environment Interaction |
2 | Gene Frequency |
2 | Gastrointestinal Tract |
2 | Frontotemporal Lobar Degeneration |
2 | Family Health |
2 | Eye Movements |
2 | Exome |
2 | European Continental Ancestry Group |
2 | Eukaryotic Initiation Factor-4G |
2 | Enzyme Inhibitors |
2 | Embryo, Mammalian |
2 | Electroencephalography |
2 | Drug Therapy, Combination |
2 | Drug Delivery Systems |
2 | Dopamine Agonists |
2 | Dominance, Cerebral |
2 | Disruptive, Impulse Control, and Conduct Disorders |
2 | Diagnosis, Differential |
2 | Deglutition Disorders |
2 | Databases, Bibliographic |
2 | Cues |
2 | Cost-Benefit Analysis |
2 | Conserved Sequence |
2 | Compulsive Behavior |
2 | Comorbidity |
2 | Cohort Studies |
2 | Coffee |
2 | Cluster Analysis |
2 | Cholinergic Neurons |
2 | Child |
2 | Cerebral Cortex |
2 | Cause of Death |
2 | Caspases |
2 | Caspase 3 |
2 | Carrier Proteins |
2 | Calbindins |
2 | COS Cells |
2 | Brain Mapping |
2 | Base Sequence |
2 | Autophagy |
2 | Apolipoproteins E |
2 | Anxiety Disorders |
2 | Amyotrophic Lateral Sclerosis |
2 | Amino Acid Sequence |
2 | Aging |
2 | Age Distribution |
2 | Affect |
2 | Administration, Oral |
1 | Wakefulness |
1 | Voice |
1 | Vocalization, Animal |
1 | Vitis |
1 | Virulence |
1 | Victoria |
1 | Vibration |
1 | Vesicular Transport Proteins |
1 | Ventricular Dysfunction, Left |
1 | Urotensins |
1 | Urea |
1 | Up-Regulation |
1 | United Kingdom |
1 | Ubiquitins |
1 | Turkey |
1 | Tumor Suppressor Protein p53 |
1 | Triazoles |
1 | Transferrin |
1 | Transdermal Patch |
1 | Transcriptome |
1 | Transcription, Genetic |
1 | Transcription Factors |
1 | Transcranial Magnetic Stimulation |
1 | Toxoplasma |
1 | Tourette Syndrome |
1 | Tomography, X-Ray Computed |
1 | Toll-Like Receptor 3 |
1 | Tissue Distribution |
1 | Thromboembolism |
1 | Thalamic Nuclei |
1 | Terminal Care |
1 | Temperature |
1 | Telomere |
1 | Telomere Shortening |
1 | Telencephalon |
1 | TOR Serine-Threonine Kinases |
1 | TATA-Box Binding Protein |
1 | Synucleins |
1 | Synteny |
1 | Synaptosomes |
1 | Synapses |
1 | Swimming |
1 | Surface Properties |
1 | Substance P |
1 | Stilbenes |
1 | Stem Cell Niche |
1 | Speech |
1 | Species Specificity |
1 | Solubility |
1 | Sodium-Potassium-Exchanging ATPase |
1 | Socioeconomic Factors |
1 | Sleep, REM |
1 | Sleep Disorders, Intrinsic |
1 | Sleep Deprivation |
1 | Signal Processing, Computer-Assisted |
1 | Siblings |
1 | Shaw Potassium Channels |
1 | Serotonin Syndrome |
1 | Serotonin 5-HT2 Receptor Agonists |
1 | Serotonin 5-HT1 Receptor Agonists |
1 | Sequence Alignment |
1 | Sensitivity and Specificity |
1 | Secosteroids |
1 | Saccharomyces cerevisiae Proteins |
1 | Saccades |
1 | Ryanodine Receptor Calcium Release Channel |
1 | Rivastigmine |
1 | Risk |
1 | Risk Reduction Behavior |
1 | Ribosomal Protein S6 Kinases, 90-kDa |
1 | Retrospective Studies |
1 | Restriction Mapping |
1 | Respiration |
1 | Residence Characteristics |
1 | Research Design |
1 | Regression Analysis |
1 | Regional Blood Flow |
1 | Referral and Consultation |
1 | Recombinant Fusion Proteins |
1 | Recognition (Psychology) |
1 | Receptors, Transferrin |
1 | Receptors, Opioid |
1 | Receptors, N-Methyl-D-Aspartate |
1 | Receptors, Immunologic |
1 | Receptors, Growth Factor |
1 | Receptors, Dopamine D2 |
1 | Receptor, Metabotropic Glutamate 5 |
1 | Receptor, Melanocortin, Type 1 |
1 | Receptor Protein-Tyrosine Kinases |
1 | Rats, Wistar |
1 | Rats, Inbred Strains |
1 | ROC Curve |
1 | RNA, Double-Stranded |
1 | RNA Polymerase II |
1 | Quantitative Trait Loci |
1 | Quality-Adjusted Life Years |
1 | Pyrimidines |
1 | PubMed |
1 | Psychotic Disorders |
1 | Protozoan Proteins |
1 | Proton-Translocating ATPases |
1 | Proto-Oncogene Proteins |
1 | Proto-Oncogene Proteins c-fos |
1 | Proteolysis |
1 | Proteins |
1 | Protein Structure, Secondary |
1 | Protein Structure, Quaternary |
1 | Protein S |
1 | Protein Interaction Maps |
1 | Protein Deglycase DJ-1 |
1 | Protein Conformation |
1 | Protein Biosynthesis |
1 | Protein Binding |
1 | Protein Aggregation, Pathological |
1 | Protein Aggregates |
1 | Prospective Studies |
1 | Promoter Regions, Genetic |
1 | Prognosis |
1 | Prion Proteins |
1 | Principal Component Analysis |
1 | Prevalence |
1 | Pressure |
1 | Preoperative Care |
1 | Practice Guidelines as Topic |
1 | Postoperative Period |
1 | Polysomnography |
1 | Polyglutamic Acid |
1 | Poly I-C |
1 | Pneumonia, Aspiration |
1 | Physical Endurance |
1 | Phylogeny |
1 | Photic Stimulation |
1 | Phosphoproteins |
1 | Phenylcarbamates |
1 | Phagocytosis |
1 | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha |
1 | Periaqueductal Gray |
1 | Peptide Termination Factors |
1 | Peptide Fragments |
1 | Penetrance |
1 | Patient Selection |
1 | Patient Education as Topic |
1 | Patient Compliance |
1 | Patient Access to Records |
1 | Pars Compacta |
1 | Parietal Lobe |
1 | Parasympathetic Nervous System |
1 | Paraquat |
1 | Pallidotomy |
1 | PTEN Phosphohydrolase |
1 | PPAR gamma |
1 | Oxygen Consumption |
1 | Oximes |
1 | Outcome Assessment (Health Care) |
1 | Orthopedic Equipment |
1 | Organometallic Compounds |
1 | Orexins |
1 | Oncogene Proteins |
1 | Oligopeptides |
1 | Oligonucleotide Array Sequence Analysis |
1 | Obsessive-Compulsive Disorder |
1 | Observer Variation |
1 | Obesity |
1 | Nursing Homes |
1 | Nuclear Receptor Subfamily 4, Group A, Member 2 |
1 | Nuclear Family |
1 | Nortropanes |
1 | Niemann-Pick Diseases |
1 | Neurotransmitter Agents |
1 | Neurotoxins |
1 | Neurotoxicity Syndromes |
1 | Neurosurgical Procedures |
1 | Neuroprotection |
1 | Neurophysiology |
1 | Neuroimaging |
1 | Neuroglia |
1 | Neurogenesis |
1 | Neurofeedback |
1 | Neural Networks (Computer) |
1 | Netherlands |
1 | Narcotic Antagonists |
1 | Narcolepsy |
1 | Naphthalenes |
1 | Myoclonic Epilepsies, Progressive |
1 | Myocardial Ischemia |
1 | Mutagenesis, Site-Directed |
1 | Muscle Tonus |
1 | Multivariate Analysis |
1 | Multiprotein Complexes |
1 | Multiple System Atrophy |
1 | Multiple Sclerosis |
1 | Multimodal Imaging |
1 | Motor Skills |
1 | Motivation |
1 | Motion Perception |
1 | Mood Disorders |
1 | Monoamine Oxidase |
1 | Monoamine Oxidase Inhibitors |
1 | Molecular Biology |
1 | Models, Neurological |
1 | Models, Chemical |
1 | Mitochondrial Proteins |
1 | Mitochondrial Dynamics |
1 | Mitochondrial Diseases |
1 | Microscopy, Electron |
1 | Microscopy, Electron, Transmission |
1 | Microscopy, Electron, Scanning Transmission |
1 | Microbiota |
1 | Metabolic Syndrome X |
1 | Metabolic Networks and Pathways |
1 | Meta-Analysis as Topic |
1 | Mercury Compounds |
1 | Mental Disorders |
1 | Memory |
1 | Memory Disorders |
1 | Membrane Potential, Mitochondrial |
1 | Melanoma |
1 | Medical Illustration |
1 | Mass Spectrometry |
1 | Macrolides |
1 | Macaca |
1 | Lysosomes |
1 | Loss of Heterozygosity |
1 | Longitudinal Studies |
1 | Locomotion |
1 | Linkage Disequilibrium |
1 | Ligases |
1 | Ligands |
1 | Laughter |
1 | Lab-On-A-Chip Devices |
1 | Japan |
1 | Italy |
1 | Iron-Binding Proteins |
1 | Ions |
1 | Intracellular Signaling Peptides and Proteins |
1 | Intermediate Filaments |
1 | Interferon-gamma |
1 | Intercellular Signaling Peptides and Proteins |
1 | Insulin Resistance |
1 | Injections |
1 | Infection |
1 | Infant |
1 | Indoles |
1 | Incidence |
1 | Impulsive Behavior |
1 | Immunoprecipitation |
1 | Immunoblotting |
1 | Immune System |
1 | Immune Sera |
1 | Imidazoles |
1 | Imaging, Three-Dimensional |
1 | Image Processing, Computer-Assisted |
1 | Hypokinesia |
1 | Huntingtin Protein |
1 | Hospitals |
1 | Hospitals, Urban |
1 | Hospital Bed Capacity |