ParkinsonFranceV1, PubMed, Corpus, bibRecord, 001775

Deterioration of dopaminergic pathways and alterations in cognition and motor functions.

Identifieur interne : 001775 ( PubMed/Corpus ); précédent : 001774; suivant : 001776

Deterioration of dopaminergic pathways and alterations in cognition and motor functions.

Auteurs : B. Dubois ; B. Pillon ; Y. Agid

Source :

Journal of neurology [ 0340-5354 ] ; 1992.

RBID : pubmed:1634910

English descriptors

KwdEn :
- Cognition Disorders (physiopathology), Dopamine (physiology), Humans, Mood Disorders (physiopathology), Nerve Degeneration (physiology), Parkinson Disease (physiopathology), Psychomotor Disorders (physiopathology).
MESH :
- chemical , physiology : Dopamine.
- physiology : Nerve Degeneration.
- physiopathology : Cognition Disorders, Mood Disorders, Parkinson Disease, Psychomotor Disorders.
- Humans.

Abstract

Degeneration of central dopaminergic neurons is the most characteristic pathological feature of Parkinson's disease. It remains to be established to what extent these lesions explain the motor, cognitive and affective disorders observed in patients, but there are now some interesting clues to a possible solution.

PubMed: 1634910

Links to Exploration step

pubmed:1634910

Le document en format XML

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<author><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B" last="Dubois">B. Dubois</name>
<affiliation><nlm:affiliation>INSERM U 289, Hôpital de la Salpêtrière, Paris, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B" last="Pillon">B. Pillon</name>
</author>
<author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y" last="Agid">Y. Agid</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Deterioration of dopaminergic pathways and alterations in cognition and motor functions.</title>
<author><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B" last="Dubois">B. Dubois</name>
<affiliation><nlm:affiliation>INSERM U 289, Hôpital de la Salpêtrière, Paris, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B" last="Pillon">B. Pillon</name>
</author>
<author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y" last="Agid">Y. Agid</name>
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<series><title level="j">Journal of neurology</title>
<idno type="ISSN">0340-5354</idno>
<imprint><date when="1992" type="published">1992</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cognition Disorders (physiopathology)</term>
<term>Dopamine (physiology)</term>
<term>Humans</term>
<term>Mood Disorders (physiopathology)</term>
<term>Nerve Degeneration (physiology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Psychomotor Disorders (physiopathology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Dopamine</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Nerve Degeneration</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Cognition Disorders</term>
<term>Mood Disorders</term>
<term>Parkinson Disease</term>
<term>Psychomotor Disorders</term>
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<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
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<front><div type="abstract" xml:lang="en">Degeneration of central dopaminergic neurons is the most characteristic pathological feature of Parkinson's disease. It remains to be established to what extent these lesions explain the motor, cognitive and affective disorders observed in patients, but there are now some interesting clues to a possible solution.</div>
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<Month>08</Month>
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<DateCompleted><Year>1992</Year>
<Month>08</Month>
<Day>25</Day>
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<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<Article PubModel="Print"><Journal><ISSN IssnType="Print">0340-5354</ISSN>
<JournalIssue CitedMedium="Print"><Volume>239 Suppl 1</Volume>
<PubDate><Year>1992</Year>
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<Title>Journal of neurology</Title>
<ISOAbbreviation>J. Neurol.</ISOAbbreviation>
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<ArticleTitle>Deterioration of dopaminergic pathways and alterations in cognition and motor functions.</ArticleTitle>
<Pagination><MedlinePgn>S9-12</MedlinePgn>
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<Abstract><AbstractText>Degeneration of central dopaminergic neurons is the most characteristic pathological feature of Parkinson's disease. It remains to be established to what extent these lesions explain the motor, cognitive and affective disorders observed in patients, but there are now some interesting clues to a possible solution.</AbstractText>
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<Author ValidYN="Y"><LastName>Pillon</LastName>
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<Author ValidYN="Y"><LastName>Agid</LastName>
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<Language>eng</Language>
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<MedlineJournalInfo><Country>Germany</Country>
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<ChemicalList><Chemical><RegistryNumber>VTD58H1Z2X</RegistryNumber>
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<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
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<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
</MeshHeadingList>
<NumberOfReferences>40</NumberOfReferences>
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	La maladie de Parkinson en France (serveur d'exploration)
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La maladie de Parkinson en France (serveur d'exploration)

Deterioration of dopaminergic pathways and alterations in cognition and motor functions.

Deterioration of dopaminergic pathways and alterations in cognition and motor functions.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki