Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. The French Parkinson's Disease Genetics Study Group, and the European Consortium on Genetic Susceptibility in Parkinson's Disease.
Identifieur interne : 001462 ( PubMed/Corpus ); précédent : 001461; suivant : 001463Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. The French Parkinson's Disease Genetics Study Group, and the European Consortium on Genetic Susceptibility in Parkinson's Disease.
Auteurs : J. Tassin ; A. Dürr ; T. De Broucker ; N. Abbas ; V. Bonifati ; G. De Michele ; A M Bonnet ; E. Broussolle ; P. Pollak ; M. Vidailhet ; M. De Mari ; R. Marconi ; S. Medjbeur ; A. Filla ; G. Meco ; Y. Agid ; A. BriceSource :
- American journal of human genetics [ 0002-9297 ] ; 1998.
English descriptors
- KwdEn :
- Age of Onset, Chromosome Mapping, Chromosomes, Human, Pair 6 (genetics), Female, Genes, Recessive (genetics), Genetic Linkage, Haplotypes (genetics), Humans, Lod Score, Male, Microsatellite Repeats (genetics), Parkinson Disease (ethnology), Parkinson Disease (genetics), Pedigree, Sequence Deletion (genetics).
- MESH :
- ethnology : Parkinson Disease.
- genetics : Chromosomes, Human, Pair 6, Genes, Recessive, Haplotypes, Microsatellite Repeats, Parkinson Disease, Sequence Deletion.
- Age of Onset, Chromosome Mapping, Female, Genetic Linkage, Humans, Lod Score, Male, Pedigree.
Abstract
The gene for autosomal recessive juvenile Parkinsonism (AR-JP) recently has been mapped to chromosome 6q25.2-27 in Japanese families. We have tested one Algerian and 10 European multiplex families with early-onset Parkinson disease for linkage to this locus, with marker D6S305. Homogeneity analysis provided a conditional probability in favor of linkage of >.9 in eight families, which were analyzed further with eight microsatellite markers spanning the 17-cM AR-JP region. Haplotype reconstruction for eight families and determination of the smallest region of homozygosity in two consanguineous families reduced the candidate interval to 11.3 cM. If the deletion of two microsatellite markers (D6S411 and D6S1550) that colocalize on the genetic map and that segregate with the disease in the Algerian family is taken into account, the candidate region would be reduced to <1 cM. These findings should facilitate identification of the corresponding gene. We have confirmed linkage of AR-JP, in European families and in an Algerian family, to the PARK2 locus. PARK2 appears to be an important locus for AR-JP in European patients. The clinical spectrum of the disease in our families, with age at onset <=58 years and the presence of painful dystonia in some patients, is broader than that reported previously.
PubMed: 9634531
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. The French Parkinson's Disease Genetics Study Group, and the European Consortium on Genetic Susceptibility in Parkinson's Disease.</title><author><name sortKey="Tassin, J" sort="Tassin, J" uniqKey="Tassin J" first="J" last="Tassin">J. Tassin</name><affiliation><nlm:affiliation>INSERM U289, Hôpital de la Salpêtière, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Durr, A" sort="Durr, A" uniqKey="Durr A" first="A" last="Dürr">A. Dürr</name></author><author><name sortKey="De Broucker, T" sort="De Broucker, T" uniqKey="De Broucker T" first="T" last="De Broucker">T. De Broucker</name></author><author><name sortKey="Abbas, N" sort="Abbas, N" uniqKey="Abbas N" first="N" last="Abbas">N. Abbas</name></author><author><name sortKey="Bonifati, V" sort="Bonifati, V" uniqKey="Bonifati V" first="V" last="Bonifati">V. Bonifati</name></author><author><name sortKey="De Michele, G" sort="De Michele, G" uniqKey="De Michele G" first="G" last="De Michele">G. De Michele</name></author><author><name sortKey="Bonnet, A M" sort="Bonnet, A M" uniqKey="Bonnet A" first="A M" last="Bonnet">A M Bonnet</name></author><author><name sortKey="Broussolle, E" sort="Broussolle, E" uniqKey="Broussolle E" first="E" last="Broussolle">E. Broussolle</name></author><author><name sortKey="Pollak, P" sort="Pollak, P" uniqKey="Pollak P" first="P" last="Pollak">P. Pollak</name></author><author><name sortKey="Vidailhet, M" sort="Vidailhet, M" uniqKey="Vidailhet M" first="M" last="Vidailhet">M. Vidailhet</name></author><author><name sortKey="De Mari, M" sort="De Mari, M" uniqKey="De Mari M" first="M" last="De Mari">M. De Mari</name></author><author><name sortKey="Marconi, R" sort="Marconi, R" uniqKey="Marconi R" first="R" last="Marconi">R. Marconi</name></author><author><name sortKey="Medjbeur, S" sort="Medjbeur, S" uniqKey="Medjbeur S" first="S" last="Medjbeur">S. Medjbeur</name></author><author><name sortKey="Filla, A" sort="Filla, A" uniqKey="Filla A" first="A" last="Filla">A. Filla</name></author><author><name sortKey="Meco, G" sort="Meco, G" uniqKey="Meco G" first="G" last="Meco">G. Meco</name></author><author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y" last="Agid">Y. Agid</name></author><author><name sortKey="Brice, A" sort="Brice, A" uniqKey="Brice A" first="A" last="Brice">A. Brice</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1998">1998</date><idno type="RBID">pubmed:9634531</idno><idno type="pmid">9634531</idno><idno type="wicri:Area/PubMed/Corpus">001462</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001462</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. The French Parkinson's Disease Genetics Study Group, and the European Consortium on Genetic Susceptibility in Parkinson's Disease.</title><author><name sortKey="Tassin, J" sort="Tassin, J" uniqKey="Tassin J" first="J" last="Tassin">J. Tassin</name><affiliation><nlm:affiliation>INSERM U289, Hôpital de la Salpêtière, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Durr, A" sort="Durr, A" uniqKey="Durr A" first="A" last="Dürr">A. Dürr</name></author><author><name sortKey="De Broucker, T" sort="De Broucker, T" uniqKey="De Broucker T" first="T" last="De Broucker">T. De Broucker</name></author><author><name sortKey="Abbas, N" sort="Abbas, N" uniqKey="Abbas N" first="N" last="Abbas">N. Abbas</name></author><author><name sortKey="Bonifati, V" sort="Bonifati, V" uniqKey="Bonifati V" first="V" last="Bonifati">V. Bonifati</name></author><author><name sortKey="De Michele, G" sort="De Michele, G" uniqKey="De Michele G" first="G" last="De Michele">G. De Michele</name></author><author><name sortKey="Bonnet, A M" sort="Bonnet, A M" uniqKey="Bonnet A" first="A M" last="Bonnet">A M Bonnet</name></author><author><name sortKey="Broussolle, E" sort="Broussolle, E" uniqKey="Broussolle E" first="E" last="Broussolle">E. Broussolle</name></author><author><name sortKey="Pollak, P" sort="Pollak, P" uniqKey="Pollak P" first="P" last="Pollak">P. Pollak</name></author><author><name sortKey="Vidailhet, M" sort="Vidailhet, M" uniqKey="Vidailhet M" first="M" last="Vidailhet">M. Vidailhet</name></author><author><name sortKey="De Mari, M" sort="De Mari, M" uniqKey="De Mari M" first="M" last="De Mari">M. De Mari</name></author><author><name sortKey="Marconi, R" sort="Marconi, R" uniqKey="Marconi R" first="R" last="Marconi">R. Marconi</name></author><author><name sortKey="Medjbeur, S" sort="Medjbeur, S" uniqKey="Medjbeur S" first="S" last="Medjbeur">S. Medjbeur</name></author><author><name sortKey="Filla, A" sort="Filla, A" uniqKey="Filla A" first="A" last="Filla">A. Filla</name></author><author><name sortKey="Meco, G" sort="Meco, G" uniqKey="Meco G" first="G" last="Meco">G. Meco</name></author><author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y" last="Agid">Y. Agid</name></author><author><name sortKey="Brice, A" sort="Brice, A" uniqKey="Brice A" first="A" last="Brice">A. Brice</name></author></analytic><series><title level="j">American journal of human genetics</title><idno type="ISSN">0002-9297</idno><imprint><date when="1998" type="published">1998</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age of Onset</term><term>Chromosome Mapping</term><term>Chromosomes, Human, Pair 6 (genetics)</term><term>Female</term><term>Genes, Recessive (genetics)</term><term>Genetic Linkage</term><term>Haplotypes (genetics)</term><term>Humans</term><term>Lod Score</term><term>Male</term><term>Microsatellite Repeats (genetics)</term><term>Parkinson Disease (ethnology)</term><term>Parkinson Disease (genetics)</term><term>Pedigree</term><term>Sequence Deletion (genetics)</term></keywords><keywords scheme="MESH" qualifier="ethnology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Chromosomes, Human, Pair 6</term><term>Genes, Recessive</term><term>Haplotypes</term><term>Microsatellite Repeats</term><term>Parkinson Disease</term><term>Sequence Deletion</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Age of Onset</term><term>Chromosome Mapping</term><term>Female</term><term>Genetic Linkage</term><term>Humans</term><term>Lod Score</term><term>Male</term><term>Pedigree</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The gene for autosomal recessive juvenile Parkinsonism (AR-JP) recently has been mapped to chromosome 6q25.2-27 in Japanese families. We have tested one Algerian and 10 European multiplex families with early-onset Parkinson disease for linkage to this locus, with marker D6S305. Homogeneity analysis provided a conditional probability in favor of linkage of >.9 in eight families, which were analyzed further with eight microsatellite markers spanning the 17-cM AR-JP region. Haplotype reconstruction for eight families and determination of the smallest region of homozygosity in two consanguineous families reduced the candidate interval to 11.3 cM. If the deletion of two microsatellite markers (D6S411 and D6S1550) that colocalize on the genetic map and that segregate with the disease in the Algerian family is taken into account, the candidate region would be reduced to <1 cM. These findings should facilitate identification of the corresponding gene. We have confirmed linkage of AR-JP, in European families and in an Algerian family, to the PARK2 locus. PARK2 appears to be an important locus for AR-JP in European patients. The clinical spectrum of the disease in our families, with age at onset <=58 years and the presence of painful dystonia in some patients, is broader than that reported previously.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">9634531</PMID><DateCreated><Year>1998</Year><Month>08</Month><Day>13</Day></DateCreated><DateCompleted><Year>1998</Year><Month>08</Month><Day>13</Day></DateCompleted><DateRevised><Year>2014</Year><Month>06</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0002-9297</ISSN><JournalIssue CitedMedium="Print"><Volume>63</Volume><Issue>1</Issue><PubDate><Year>1998</Year><Month>Jul</Month></PubDate></JournalIssue><Title>American journal of human genetics</Title><ISOAbbreviation>Am. J. Hum. Genet.</ISOAbbreviation></Journal><ArticleTitle>Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. The French Parkinson's Disease Genetics Study Group, and the European Consortium on Genetic Susceptibility in Parkinson's Disease.</ArticleTitle><Pagination><MedlinePgn>88-94</MedlinePgn></Pagination><Abstract><AbstractText>The gene for autosomal recessive juvenile Parkinsonism (AR-JP) recently has been mapped to chromosome 6q25.2-27 in Japanese families. We have tested one Algerian and 10 European multiplex families with early-onset Parkinson disease for linkage to this locus, with marker D6S305. Homogeneity analysis provided a conditional probability in favor of linkage of >.9 in eight families, which were analyzed further with eight microsatellite markers spanning the 17-cM AR-JP region. Haplotype reconstruction for eight families and determination of the smallest region of homozygosity in two consanguineous families reduced the candidate interval to 11.3 cM. If the deletion of two microsatellite markers (D6S411 and D6S1550) that colocalize on the genetic map and that segregate with the disease in the Algerian family is taken into account, the candidate region would be reduced to <1 cM. These findings should facilitate identification of the corresponding gene. We have confirmed linkage of AR-JP, in European families and in an Algerian family, to the PARK2 locus. PARK2 appears to be an important locus for AR-JP in European patients. The clinical spectrum of the disease in our families, with age at onset <=58 years and the presence of painful dystonia in some patients, is broader than that reported previously.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tassin</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>INSERM U289, Hôpital de la Salpêtière, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dürr</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>de Broucker</LastName><ForeName>T</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Abbas</LastName><ForeName>N</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Bonifati</LastName><ForeName>V</ForeName><Initials>V</Initials></Author><Author ValidYN="Y"><LastName>De Michele</LastName><ForeName>G</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Bonnet</LastName><ForeName>A M</ForeName><Initials>AM</Initials></Author><Author ValidYN="Y"><LastName>Broussolle</LastName><ForeName>E</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Pollak</LastName><ForeName>P</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Vidailhet</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>De Mari</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Marconi</LastName><ForeName>R</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Medjbeur</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Filla</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Meco</LastName><ForeName>G</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Agid</LastName><ForeName>Y</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Brice</LastName><ForeName>A</ForeName><Initials>A</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Am J Hum Genet</MedlineTA><NlmUniqueID>0370475</NlmUniqueID><ISSNLinking>0002-9297</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Neurology. 1973 Mar;23(3):239-44</RefSource><PMID Version="1">4735177</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Hum Genet. 1998;43(1):22-31</RefSource><PMID Version="1">9609994</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 1987;2(2):73-91</RefSource><PMID Version="1">3504266</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 1991 Jun 1;337(8753):1321-4</RefSource><PMID Version="1">1674304</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Rinsho Shinkeigaku. 1993 May;33(5):491-6</RefSource><PMID Version="1">8365054</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 1994 Jan;54(1):11-20</RefSource><PMID Version="1">8279460</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 1994 Mar;44(3 Pt 1):437-41</RefSource><PMID Version="1">8145912</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Hum Hered. 1994 Jul-Aug;44(4):225-37</RefSource><PMID Version="1">8056435</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 1996 Mar 14;380(6570):152-4</RefSource><PMID Version="1">8600387</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 1996 Jul;47(1):160-6</RefSource><PMID Version="1">8710071</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Science. 1996 Nov 15;274(5290):1197-9</RefSource><PMID Version="1">8895469</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 1997 Mar;60(3):588-96</RefSource><PMID Version="1">9042918</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 1997 Apr;62(4):305-9</RefSource><PMID Version="1">9120440</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Science. 1997 Jun 27;276(5321):2045-7</RefSource><PMID Version="1">9197268</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 1998 Feb;18(2):106-8</RefSource><PMID Version="1">9462735</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 1998 Mar;18(3):262-5</RefSource><PMID Version="1">9500549</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 1998 Apr 9;392(6676):605-8</RefSource><PMID Version="1">9560156</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 1985 May;37(3):482-98</RefSource><PMID Version="1">3859205</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D017668" MajorTopicYN="N">Age of Onset</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002874" MajorTopicYN="N">Chromosome Mapping</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002896" MajorTopicYN="N">Chromosomes, Human, Pair 6</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005808" MajorTopicYN="N">Genes, Recessive</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008040" MajorTopicYN="N">Genetic Linkage</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006239" MajorTopicYN="N">Haplotypes</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008126" MajorTopicYN="N">Lod Score</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018895" MajorTopicYN="N">Microsatellite Repeats</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName><QualifierName UI="Q000208" MajorTopicYN="Y">ethnology</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010375" MajorTopicYN="N">Pedigree</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017384" MajorTopicYN="N">Sequence Deletion</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC1377254</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1998</Year><Month>6</Month><Day>23</Day><Hour>2</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2000</Year><Month>3</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1998</Year><Month>6</Month><Day>23</Day><Hour>2</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">9634531</ArticleId><ArticleId IdType="pii">S0002-9297(07)60774-5</ArticleId><ArticleId IdType="pmc">PMC1377254</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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