La maladie de Parkinson en France (serveur d'exploration)

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Iodine-123 fluoropropyl-carbomethoxy-3-β-(4-iodophenyltropane) single-photon emission computed tomography findings before and after electroconvulsive therapy in major depressive disorder with Parkinsonism.

Identifieur interne : 000924 ( PubMed/Corpus ); précédent : 000923; suivant : 000925

Iodine-123 fluoropropyl-carbomethoxy-3-β-(4-iodophenyltropane) single-photon emission computed tomography findings before and after electroconvulsive therapy in major depressive disorder with Parkinsonism.

Auteurs : Eric Bui ; Julien Delrieu ; Thomas Wagner ; Julie Rieu ; Etienne Véry ; Clara Letamendia ; Pierre Payoux ; Laurent Schmitt

Source :

RBID : pubmed:21709584

English descriptors

Abstract

To date, only a few cases of improvement of Parkinsonism in depressed patients treated with electroconvulsive therapy (ECT) have been reported. However, no functional imaging data are available to support this finding.

DOI: 10.1097/YCT.0b013e31821646b6
PubMed: 21709584

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pubmed:21709584

Le document en format XML

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<title xml:lang="en">Iodine-123 fluoropropyl-carbomethoxy-3-β-(4-iodophenyltropane) single-photon emission computed tomography findings before and after electroconvulsive therapy in major depressive disorder with Parkinsonism.</title>
<author>
<name sortKey="Bui, Eric" sort="Bui, Eric" uniqKey="Bui E" first="Eric" last="Bui">Eric Bui</name>
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<nlm:affiliation>Laboratoire du Stress Traumatique, Université de Toulouse, Toulouse, France. bui.e@chu-toulouse.fr</nlm:affiliation>
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<name sortKey="Delrieu, Julien" sort="Delrieu, Julien" uniqKey="Delrieu J" first="Julien" last="Delrieu">Julien Delrieu</name>
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<name sortKey="Wagner, Thomas" sort="Wagner, Thomas" uniqKey="Wagner T" first="Thomas" last="Wagner">Thomas Wagner</name>
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<name sortKey="Rieu, Julie" sort="Rieu, Julie" uniqKey="Rieu J" first="Julie" last="Rieu">Julie Rieu</name>
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<name sortKey="Very, Etienne" sort="Very, Etienne" uniqKey="Very E" first="Etienne" last="Véry">Etienne Véry</name>
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<name sortKey="Letamendia, Clara" sort="Letamendia, Clara" uniqKey="Letamendia C" first="Clara" last="Letamendia">Clara Letamendia</name>
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<name sortKey="Payoux, Pierre" sort="Payoux, Pierre" uniqKey="Payoux P" first="Pierre" last="Payoux">Pierre Payoux</name>
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<name sortKey="Schmitt, Laurent" sort="Schmitt, Laurent" uniqKey="Schmitt L" first="Laurent" last="Schmitt">Laurent Schmitt</name>
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<term>Aged</term>
<term>Depressive Disorder, Major (complications)</term>
<term>Depressive Disorder, Major (therapy)</term>
<term>Dopamine Plasma Membrane Transport Proteins (metabolism)</term>
<term>Electroconvulsive Therapy</term>
<term>Humans</term>
<term>Iodine Radioisotopes</term>
<term>Male</term>
<term>Parkinsonian Disorders (complications)</term>
<term>Parkinsonian Disorders (therapy)</term>
<term>Tomography, Emission-Computed, Single-Photon</term>
<term>Treatment Outcome</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en">
<term>Dopamine Plasma Membrane Transport Proteins</term>
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<term>Depressive Disorder, Major</term>
<term>Parkinsonian Disorders</term>
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<term>Depressive Disorder, Major</term>
<term>Parkinsonian Disorders</term>
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<keywords scheme="MESH" xml:lang="en">
<term>Aged</term>
<term>Electroconvulsive Therapy</term>
<term>Humans</term>
<term>Iodine Radioisotopes</term>
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<div type="abstract" xml:lang="en">To date, only a few cases of improvement of Parkinsonism in depressed patients treated with electroconvulsive therapy (ECT) have been reported. However, no functional imaging data are available to support this finding.</div>
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<Title>The journal of ECT</Title>
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<ArticleTitle>Iodine-123 fluoropropyl-carbomethoxy-3-β-(4-iodophenyltropane) single-photon emission computed tomography findings before and after electroconvulsive therapy in major depressive disorder with Parkinsonism.</ArticleTitle>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">To date, only a few cases of improvement of Parkinsonism in depressed patients treated with electroconvulsive therapy (ECT) have been reported. However, no functional imaging data are available to support this finding.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To describe the first observation of increase in dopamine transporter uptake after ECT.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Iodine-123 fluoropropyl-carbomethoxy-3-β-(4-iodophenyltropane) single-photon emission computed tomographic imaging was conducted in a 77-year-old depressed patient displaying symptoms of Parkinson disease (PD) before and after a series of 12 bilateral ECTs.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The patient displayed improvement in PD symptoms and increase in dopamine transporter uptake after ECT.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Our observation suggests that the PD symptoms and decrease in striatal uptake appearing in the context of a depressive episode might warrant further attention, as they might be reversible.</AbstractText>
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