Does bilateral stimulation of the subthalamic nucleus aggravate apathy in Parkinson's disease?. Commentary
Identifieur interne : 000755 ( PascalFrancis/Curation ); précédent : 000754; suivant : 000756Does bilateral stimulation of the subthalamic nucleus aggravate apathy in Parkinson's disease?. Commentary
Auteurs : M. Samuel [Royaume-Uni] ; V. Voon [États-Unis] ; V. Czernecki [France] ; B. Pillon [France] ; J. L. Houeto [France] ; M. L. Welter [France] ; V. Mesnage [France] ; Y. Agid [France] ; B. Dubois [France]Source :
- Journal of neurology, neurosurgery and psychiatry [ 0022-3050 ] ; 2005.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
Objective: High frequency stimulation of the subthalamic nucleus (STN) dramatically decreases motor disability in patients with Parkinson"s disease (PD), but has been reported to aggravate apathy. The aim of this study was to analyse the effect of STN stimulation on motivation and reward sensitivity in a consecutive series of PD patients. Methods: Apathy and reward sensitivity (Apathy Scale, Stimulus-Reward Learning, Reversal, Extinction, and Gambling tasks) were assessed in 18 PD patients treated by bilateral STN stimulation ("on" and "off" conditions) compared with 23 matched patients undergoing long term treatment with levodopa ("on" and "off" conditions). Results: Apathy decreased under both STN stimulation and levodopa treatment, whereas explicit and implicit stimulus reward learning was unchanged. Conclusions: Bilateral STN stimulation in PD patients does not necessarily have a negative effect on motivation and reward sensitivity and can even improve apathy provided patients have been appropriately selected for neurosurgery.
pA |
|
---|
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000C79
Links to Exploration step
Pascal:05-0290586Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Does bilateral stimulation of the subthalamic nucleus aggravate apathy in Parkinson's disease?. Commentary</title>
<author><name sortKey="Samuel, M" sort="Samuel, M" uniqKey="Samuel M" first="M." last="Samuel">M. Samuel</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, King's College Hospital</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
</affiliation>
</author>
<author><name sortKey="Voon, V" sort="Voon, V" uniqKey="Voon V" first="V." last="Voon">V. Voon</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>National Institutes of Neurological Disorders and Stroke, National Institute of Health</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Czernecki, V" sort="Czernecki, V" uniqKey="Czernecki V" first="V." last="Czernecki">V. Czernecki</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>INSERM U 610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B." last="Pillon">B. Pillon</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>INSERM U 610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Houeto, J L" sort="Houeto, J L" uniqKey="Houeto J" first="J. L." last="Houeto">J. L. Houeto</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Welter, M L" sort="Welter, M L" uniqKey="Welter M" first="M. L." last="Welter">M. L. Welter</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Mesnage, V" sort="Mesnage, V" uniqKey="Mesnage V" first="V." last="Mesnage">V. Mesnage</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y." last="Agid">Y. Agid</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B." last="Dubois">B. Dubois</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>INSERM U 610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">05-0290586</idno>
<date when="2005">2005</date>
<idno type="stanalyst">PASCAL 05-0290586 INIST</idno>
<idno type="RBID">Pascal:05-0290586</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000C79</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000755</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Does bilateral stimulation of the subthalamic nucleus aggravate apathy in Parkinson's disease?. Commentary</title>
<author><name sortKey="Samuel, M" sort="Samuel, M" uniqKey="Samuel M" first="M." last="Samuel">M. Samuel</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, King's College Hospital</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
</affiliation>
</author>
<author><name sortKey="Voon, V" sort="Voon, V" uniqKey="Voon V" first="V." last="Voon">V. Voon</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>National Institutes of Neurological Disorders and Stroke, National Institute of Health</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Czernecki, V" sort="Czernecki, V" uniqKey="Czernecki V" first="V." last="Czernecki">V. Czernecki</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>INSERM U 610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B." last="Pillon">B. Pillon</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>INSERM U 610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Houeto, J L" sort="Houeto, J L" uniqKey="Houeto J" first="J. L." last="Houeto">J. L. Houeto</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Welter, M L" sort="Welter, M L" uniqKey="Welter M" first="M. L." last="Welter">M. L. Welter</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Mesnage, V" sort="Mesnage, V" uniqKey="Mesnage V" first="V." last="Mesnage">V. Mesnage</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y." last="Agid">Y. Agid</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B." last="Dubois">B. Dubois</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>INSERM U 610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of neurology, neurosurgery and psychiatry</title>
<title level="j" type="abbreviated">J. neurol. neurosurg. psychiatry</title>
<idno type="ISSN">0022-3050</idno>
<imprint><date when="2005">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of neurology, neurosurgery and psychiatry</title>
<title level="j" type="abbreviated">J. neurol. neurosurg. psychiatry</title>
<idno type="ISSN">0022-3050</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Nervous system diseases</term>
<term>Parkinson disease</term>
<term>Subthalamic nucleus</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Parkinson maladie</term>
<term>Noyau sousthalamique</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Objective: High frequency stimulation of the subthalamic nucleus (STN) dramatically decreases motor disability in patients with Parkinson"s disease (PD), but has been reported to aggravate apathy. The aim of this study was to analyse the effect of STN stimulation on motivation and reward sensitivity in a consecutive series of PD patients. Methods: Apathy and reward sensitivity (Apathy Scale, Stimulus-Reward Learning, Reversal, Extinction, and Gambling tasks) were assessed in 18 PD patients treated by bilateral STN stimulation ("on" and "off" conditions) compared with 23 matched patients undergoing long term treatment with levodopa ("on" and "off" conditions). Results: Apathy decreased under both STN stimulation and levodopa treatment, whereas explicit and implicit stimulus reward learning was unchanged. Conclusions: Bilateral STN stimulation in PD patients does not necessarily have a negative effect on motivation and reward sensitivity and can even improve apathy provided patients have been appropriately selected for neurosurgery.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0022-3050</s0>
</fA01>
<fA02 i1="01"><s0>JNNPAU</s0>
</fA02>
<fA03 i2="1"><s0>J. neurol. neurosurg. psychiatry</s0>
</fA03>
<fA05><s2>76</s2>
</fA05>
<fA06><s2>6</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Does bilateral stimulation of the subthalamic nucleus aggravate apathy in Parkinson's disease?. Commentary</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>SAMUEL (M.)</s1>
<s9>comment.</s9>
</fA11>
<fA11 i1="02" i2="1"><s1>VOON (V.)</s1>
<s9>comment.</s9>
</fA11>
<fA11 i1="03" i2="1"><s1>CZERNECKI (V.)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>PILLON (B.)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>HOUETO (J. L.)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>WELTER (M. L.)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>MESNAGE (V.)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>AGID (Y.)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>DUBOIS (B.)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Neurology, King's College Hospital</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>National Institutes of Neurological Disorders and Stroke, National Institute of Health</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>INSERM U 610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>9 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Centre d'Investigation Clinique, Fédération de Neurologie and INSERM U 289, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital</s1>
<s2>75651 Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</fA14>
<fA20><s2>759-760,775-779 [7 p.]</s2>
</fA20>
<fA21><s1>2005</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>6015</s2>
<s5>354000138053130050</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2005 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>45 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>05-0290586</s0>
</fA47>
<fA60><s1>P</s1>
<s3>AR</s3>
<s3>CT</s3>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Journal of neurology, neurosurgery and psychiatry</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Objective: High frequency stimulation of the subthalamic nucleus (STN) dramatically decreases motor disability in patients with Parkinson"s disease (PD), but has been reported to aggravate apathy. The aim of this study was to analyse the effect of STN stimulation on motivation and reward sensitivity in a consecutive series of PD patients. Methods: Apathy and reward sensitivity (Apathy Scale, Stimulus-Reward Learning, Reversal, Extinction, and Gambling tasks) were assessed in 18 PD patients treated by bilateral STN stimulation ("on" and "off" conditions) compared with 23 matched patients undergoing long term treatment with levodopa ("on" and "off" conditions). Results: Apathy decreased under both STN stimulation and levodopa treatment, whereas explicit and implicit stimulus reward learning was unchanged. Conclusions: Bilateral STN stimulation in PD patients does not necessarily have a negative effect on motivation and reward sensitivity and can even improve apathy provided patients have been appropriately selected for neurosurgery.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B17</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B17G</s0>
</fC02>
<fC02 i1="03" i2="X"><s0>002B17A03</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Parkinson maladie</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Parkinson disease</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Parkinson enfermedad</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Noyau sousthalamique</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Subthalamic nucleus</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Núcleo subtalámico</s0>
<s5>09</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Système nerveux central</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Central nervous system</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Sistema nervioso central</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>41</s5>
</fC07>
<fN21><s1>206</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/PascalFrancis/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000755 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Curation/biblio.hfd -nk 000755 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonFranceV1 |flux= PascalFrancis |étape= Curation |type= RBID |clé= Pascal:05-0290586 |texte= Does bilateral stimulation of the subthalamic nucleus aggravate apathy in Parkinson's disease?. Commentary }}
![]() | This area was generated with Dilib version V0.6.29. | ![]() |