Telomere length in Parkinson's disease: A meta-analysis.
Identifieur interne : 001919 ( Ncbi/Curation ); précédent : 001918; suivant : 001920Telomere length in Parkinson's disease: A meta-analysis.
Auteurs : Diego A. Forero [Colombie] ; Yeimy González-Giraldo [Colombie] ; Catalina L Pez-Quintero [États-Unis] ; Luis J. Castro-Vega [France] ; George E. Barreto [Chili] ; George Perry [États-Unis]Source :
- Experimental gerontology [ 1873-6815 ] ; 2016.
English descriptors
- KwdEn :
- MESH :
- genetics : Parkinson Disease.
- pathology : Telomere.
- Case-Control Studies, Humans, Risk Factors, Telomere Shortening.
Abstract
Parkinson's disease (PD) is a common and severe movement disorder. Differences in telomere length (TL) have been reported as possible risk factors for several neuropsychiatric disorders, including PD. Results from published studies for TL in PD are inconsistent, highlighting the need for a meta-analysis. In the current work, a meta-analysis of published studies for TL in PD was carried out. PubMed, Web of Science and Google Scholar databases were used to identify relevant articles that reported TL in groups of PD patients and controls. A random-effects model was used for meta-analytical procedures. The meta-analysis included eight primary studies, derived from populations of European and Asian descent, and did not show a significant difference in TL between 956 PD patients and 1284 controls (p value: 0.246). Our results show that there is no consistent evidence of shorter telomeres in PD patients and suggest the importance of future studies on TL and PD that analyze other populations and also include assessment of TL from different brain regions.
DOI: 10.1016/j.exger.2016.01.002
PubMed: 26772888
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000181
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000181
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000181
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :001919
Links to Exploration step
pubmed:26772888Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Telomere length in Parkinson's disease: A meta-analysis.</title><author><name sortKey="Forero, Diego A" sort="Forero, Diego A" uniqKey="Forero D" first="Diego A" last="Forero">Diego A. Forero</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Neuropsychiatric Genetics, Biomedical Sciences Research Group, School of Medicine, Universidad Antonio Nariño, Bogotá, Colombia. Electronic address: diego.forero@uan.edu.co.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Laboratory of Neuropsychiatric Genetics, Biomedical Sciences Research Group, School of Medicine, Universidad Antonio Nariño, Bogotá</wicri:regionArea><wicri:noRegion>Bogotá</wicri:noRegion></affiliation></author><author><name sortKey="Gonzalez Giraldo, Yeimy" sort="Gonzalez Giraldo, Yeimy" uniqKey="Gonzalez Giraldo Y" first="Yeimy" last="González-Giraldo">Yeimy González-Giraldo</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá</wicri:regionArea><wicri:noRegion>Bogotá</wicri:noRegion></affiliation></author><author><name sortKey="L Pez Quintero, Catalina" sort="L Pez Quintero, Catalina" uniqKey="L Pez Quintero C" first="Catalina" last="L Pez-Quintero">Catalina L Pez-Quintero</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI</wicri:regionArea><placeName><region type="state">Michigan</region><settlement type="city">East Lansing</settlement></placeName><orgName type="university">Université d'État du Michigan</orgName></affiliation></author><author><name sortKey="Castro Vega, Luis J" sort="Castro Vega, Luis J" uniqKey="Castro Vega L" first="Luis J" last="Castro-Vega">Luis J. Castro-Vega</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, UMR970, Paris-Cardiovascular Research Center, F-75015 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, UMR970, Paris-Cardiovascular Research Center, F-75015 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Barreto, George E" sort="Barreto, George E" uniqKey="Barreto G" first="George E" last="Barreto">George E. Barreto</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia; Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Santiago, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia; Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Santiago</wicri:regionArea><wicri:noRegion>Santiago</wicri:noRegion></affiliation></author><author><name sortKey="Perry, George" sort="Perry, George" uniqKey="Perry G" first="George" last="Perry">George Perry</name><affiliation wicri:level="2"><nlm:affiliation>College of Sciences, University of Texas at San Antonio, San Antonio, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>College of Sciences, University of Texas at San Antonio, San Antonio, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:26772888</idno><idno type="pmid">26772888</idno><idno type="doi">10.1016/j.exger.2016.01.002</idno><idno type="wicri:Area/PubMed/Corpus">000181</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000181</idno><idno type="wicri:Area/PubMed/Curation">000181</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000181</idno><idno type="wicri:Area/PubMed/Checkpoint">000181</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000181</idno><idno type="wicri:Area/Ncbi/Merge">001919</idno><idno type="wicri:Area/Ncbi/Curation">001919</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Telomere length in Parkinson's disease: A meta-analysis.</title><author><name sortKey="Forero, Diego A" sort="Forero, Diego A" uniqKey="Forero D" first="Diego A" last="Forero">Diego A. Forero</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Neuropsychiatric Genetics, Biomedical Sciences Research Group, School of Medicine, Universidad Antonio Nariño, Bogotá, Colombia. Electronic address: diego.forero@uan.edu.co.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Laboratory of Neuropsychiatric Genetics, Biomedical Sciences Research Group, School of Medicine, Universidad Antonio Nariño, Bogotá</wicri:regionArea><wicri:noRegion>Bogotá</wicri:noRegion></affiliation></author><author><name sortKey="Gonzalez Giraldo, Yeimy" sort="Gonzalez Giraldo, Yeimy" uniqKey="Gonzalez Giraldo Y" first="Yeimy" last="González-Giraldo">Yeimy González-Giraldo</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá</wicri:regionArea><wicri:noRegion>Bogotá</wicri:noRegion></affiliation></author><author><name sortKey="L Pez Quintero, Catalina" sort="L Pez Quintero, Catalina" uniqKey="L Pez Quintero C" first="Catalina" last="L Pez-Quintero">Catalina L Pez-Quintero</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI</wicri:regionArea><placeName><region type="state">Michigan</region><settlement type="city">East Lansing</settlement></placeName><orgName type="university">Université d'État du Michigan</orgName></affiliation></author><author><name sortKey="Castro Vega, Luis J" sort="Castro Vega, Luis J" uniqKey="Castro Vega L" first="Luis J" last="Castro-Vega">Luis J. Castro-Vega</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, UMR970, Paris-Cardiovascular Research Center, F-75015 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, UMR970, Paris-Cardiovascular Research Center, F-75015 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Barreto, George E" sort="Barreto, George E" uniqKey="Barreto G" first="George E" last="Barreto">George E. Barreto</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia; Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Santiago, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia; Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Santiago</wicri:regionArea><wicri:noRegion>Santiago</wicri:noRegion></affiliation></author><author><name sortKey="Perry, George" sort="Perry, George" uniqKey="Perry G" first="George" last="Perry">George Perry</name><affiliation wicri:level="2"><nlm:affiliation>College of Sciences, University of Texas at San Antonio, San Antonio, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>College of Sciences, University of Texas at San Antonio, San Antonio, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></analytic><series><title level="j">Experimental gerontology</title><idno type="eISSN">1873-6815</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Case-Control Studies</term><term>Humans</term><term>Parkinson Disease (genetics)</term><term>Risk Factors</term><term>Telomere (pathology)</term><term>Telomere Shortening</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Telomere</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Case-Control Studies</term><term>Humans</term><term>Risk Factors</term><term>Telomere Shortening</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Parkinson's disease (PD) is a common and severe movement disorder. Differences in telomere length (TL) have been reported as possible risk factors for several neuropsychiatric disorders, including PD. Results from published studies for TL in PD are inconsistent, highlighting the need for a meta-analysis. In the current work, a meta-analysis of published studies for TL in PD was carried out. PubMed, Web of Science and Google Scholar databases were used to identify relevant articles that reported TL in groups of PD patients and controls. A random-effects model was used for meta-analytical procedures. The meta-analysis included eight primary studies, derived from populations of European and Asian descent, and did not show a significant difference in TL between 956 PD patients and 1284 controls (p value: 0.246). Our results show that there is no consistent evidence of shorter telomeres in PD patients and suggest the importance of future studies on TL and PD that analyze other populations and also include assessment of TL from different brain regions.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001919 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 001919 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonFranceV1
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= pubmed:26772888
|texte= Telomere length in Parkinson's disease: A meta-analysis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:26772888" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonFranceV1
| This area was generated with Dilib version V0.6.29. |  |