Deterioration of dopaminergic pathways and alterations in cognition and motor functions.
Identifieur interne : 000574 ( Ncbi/Curation ); précédent : 000573; suivant : 000575Deterioration of dopaminergic pathways and alterations in cognition and motor functions.
Auteurs : B. Dubois [France] ; B. Pillon ; Yves Agid [France]Source :
- Journal of neurology [ 0340-5354 ] ; 1992.
English descriptors
- KwdEn :
- MESH :
- chemical , physiology : Dopamine.
- physiology : Nerve Degeneration.
- physiopathology : Cognition Disorders, Mood Disorders, Parkinson Disease, Psychomotor Disorders.
- Humans.
Abstract
Degeneration of central dopaminergic neurons is the most characteristic pathological feature of Parkinson's disease. It remains to be established to what extent these lesions explain the motor, cognitive and affective disorders observed in patients, but there are now some interesting clues to a possible solution.
PubMed: 1634910
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