Autophagy in Pancreatic Cancer
Identifieur interne : 000E41 ( Ncbi/Checkpoint ); précédent : 000E40; suivant : 000E42Autophagy in Pancreatic Cancer
Auteurs : Daniel Grasso [France] ; Maria Noé Garcia [France] ; Juan L. Iovanna [France]Source :
- International Journal of Cell Biology [ 1687-8876 ] ; 2012.
Abstract
Pancreatic adenocarcinoma (PDAC) is a devastating disease with an extremely poor life expectancy and no effective treatment. Autophagy is a process of degradation of cytoplasmic component capable of recycling cellular components or eliminate specific targets. The presence of autophagy in PDAC has been demonstrated. However, the implicated cellular pathways are not fully understood and, more importantly, the role of autophagy in PDAC is matter of intensive debate. This review summarizes recently published data in an attempt to clarify the importance of autophagy in this disease and try to reconcile apparently contradictory results.
Url:
DOI: 10.1155/2012/760498
PubMed: 22291707
PubMed Central: 3265076
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000971
- to stream Pmc, to step Curation: 000967
- to stream Pmc, to step Checkpoint: 000640
- to stream Ncbi, to step Merge: 000E41
- to stream Ncbi, to step Curation: 000E41
Links to Exploration step
PMC:3265076Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Pancreatic adenocarcinoma (PDAC) is a devastating disease with an extremely poor life expectancy and no effective treatment. Autophagy is a process of degradation of cytoplasmic component capable of recycling cellular components or eliminate specific targets. The presence of autophagy in PDAC has been demonstrated. However, the implicated cellular pathways are not fully understood and, more importantly, the role of autophagy in PDAC is matter of intensive debate. This review summarizes recently published data in an attempt to clarify the importance of autophagy in this disease and try to reconcile apparently contradictory results.</p>
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</TEI>
<affiliations><list><country><li>France</li>
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<region><li>Provence-Alpes-Côte d'Azur</li>
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<settlement><li>Marseille</li>
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<tree><country name="France"><region name="Provence-Alpes-Côte d'Azur"><name sortKey="Grasso, Daniel" sort="Grasso, Daniel" uniqKey="Grasso D" first="Daniel" last="Grasso">Daniel Grasso</name>
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