[Neuroplasticity: from physiological adaptation to the concept of therapeutic plasticity].
Identifieur interne : 000990 ( Ncbi/Checkpoint ); précédent : 000989; suivant : 000991[Neuroplasticity: from physiological adaptation to the concept of therapeutic plasticity].
Auteurs : Brigitte Onténiente [France]Source :
- Journal de la Societe de biologie [ 1295-0661 ] ; 2009.
English descriptors
- KwdEn :
- Adaptation, Physiological, Adult, Animals, Brain (physiology), Brain Ischemia (physiopathology), Brain Tissue Transplantation, Dopamine (metabolism), Fetal Tissue Transplantation, Humans, Neurogenesis, Neuronal Plasticity, Neurons (cytology), Parkinson Disease (surgery), Rats, Stem Cell Transplantation, Stem Cells (physiology).
- MESH :
- chemical , metabolism : Dopamine.
- cytology : Neurons.
- physiology : Brain, Stem Cells.
- physiopathology : Brain Ischemia.
- surgery : Parkinson Disease.
- Adaptation, Physiological, Adult, Animals, Brain Tissue Transplantation, Fetal Tissue Transplantation, Humans, Neurogenesis, Neuronal Plasticity, Rats, Stem Cell Transplantation.
Abstract
There is considerable evidence that the human brain maintains the ability to reorganize itself throughout life, an ability known as neuroplasticity. Initially demonstrated in physiological situations, neuroplasticity includes, and relies on, a number of adaptive mechanisms that include not only phenotypic modifications of neurons or synaptic reorganisation but also major modifications of brain circuitry after insults. Recently, the presence of neurogenic zones in the adult brain has unveiled a new aspect of brain plasticity that, together with emerging stem cell therapy, opens the possibility to take advantage of these natural reminders of the developmental period to repair lesioned tissues, a concept known as "therapeutic plasticity".
DOI: 10.1051/jbio:2009001
PubMed: 19358816
Affiliations:
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pubmed:19358816Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Neuroplasticity: from physiological adaptation to the concept of therapeutic plasticity].</title><author><name sortKey="Onteniente, Brigitte" sort="Onteniente, Brigitte" uniqKey="Onteniente B" first="Brigitte" last="Onténiente">Brigitte Onténiente</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, UMR 894, Centre de Recherches en Psychiatrie et Neurosciences, 2Ter rue d'Alésia, 75014 Paris, France. brigitte.onteniente@inserm.fr</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, UMR 894, Centre de Recherches en Psychiatrie et Neurosciences, 2Ter rue d'Alésia, 75014 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="RBID">pubmed:19358816</idno><idno type="pmid">19358816</idno><idno type="doi">10.1051/jbio:2009001</idno><idno type="wicri:Area/PubMed/Corpus">000C37</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000C37</idno><idno type="wicri:Area/PubMed/Curation">000B97</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000B97</idno><idno type="wicri:Area/PubMed/Checkpoint">000B97</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000B97</idno><idno type="wicri:Area/Ncbi/Merge">000990</idno><idno type="wicri:Area/Ncbi/Curation">000990</idno><idno type="wicri:Area/Ncbi/Checkpoint">000990</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Neuroplasticity: from physiological adaptation to the concept of therapeutic plasticity].</title><author><name sortKey="Onteniente, Brigitte" sort="Onteniente, Brigitte" uniqKey="Onteniente B" first="Brigitte" last="Onténiente">Brigitte Onténiente</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, UMR 894, Centre de Recherches en Psychiatrie et Neurosciences, 2Ter rue d'Alésia, 75014 Paris, France. brigitte.onteniente@inserm.fr</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, UMR 894, Centre de Recherches en Psychiatrie et Neurosciences, 2Ter rue d'Alésia, 75014 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><series><title level="j">Journal de la Societe de biologie</title><idno type="ISSN">1295-0661</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adaptation, Physiological</term><term>Adult</term><term>Animals</term><term>Brain (physiology)</term><term>Brain Ischemia (physiopathology)</term><term>Brain Tissue Transplantation</term><term>Dopamine (metabolism)</term><term>Fetal Tissue Transplantation</term><term>Humans</term><term>Neurogenesis</term><term>Neuronal Plasticity</term><term>Neurons (cytology)</term><term>Parkinson Disease (surgery)</term><term>Rats</term><term>Stem Cell Transplantation</term><term>Stem Cells (physiology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Dopamine</term></keywords><keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Neurons</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Brain</term><term>Stem Cells</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain Ischemia</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adaptation, Physiological</term><term>Adult</term><term>Animals</term><term>Brain Tissue Transplantation</term><term>Fetal Tissue Transplantation</term><term>Humans</term><term>Neurogenesis</term><term>Neuronal Plasticity</term><term>Rats</term><term>Stem Cell Transplantation</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">There is considerable evidence that the human brain maintains the ability to reorganize itself throughout life, an ability known as neuroplasticity. Initially demonstrated in physiological situations, neuroplasticity includes, and relies on, a number of adaptive mechanisms that include not only phenotypic modifications of neurons or synaptic reorganisation but also major modifications of brain circuitry after insults. Recently, the presence of neurogenic zones in the adult brain has unveiled a new aspect of brain plasticity that, together with emerging stem cell therapy, opens the possibility to take advantage of these natural reminders of the developmental period to repair lesioned tissues, a concept known as "therapeutic plasticity".</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Île-de-France</li></region><settlement><li>Paris</li></settlement></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Onteniente, Brigitte" sort="Onteniente, Brigitte" uniqKey="Onteniente B" first="Brigitte" last="Onténiente">Brigitte Onténiente</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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