ParkinsonFranceV1, Ncbi, Checkpoint, bibRecord, 000247

Behavioural disorders, Parkinson's disease and subthalamic stimulation

Identifieur interne : 000247 ( Ncbi/Checkpoint ); précédent : 000246; suivant : 000248

Behavioural disorders, Parkinson's disease and subthalamic stimulation

Auteurs : J. Houeto ; V. Mesnage ; L. Mallet ; B. Pillon ; M. Gargiulo ; S T. Du Moncel ; A. Bonnet ; B. Pidoux ; D. Dormont ; P. Cornu ; Yves Agid [France]

Source :

Journal of Neurology, Neurosurgery, and Psychiatry [ 0022-3050 ] ; 2002.

RBID : PMC:1737905

English descriptors

KwdEn :
- Anxiety (etiology), Depression (etiology), Electric Stimulation Therapy (adverse effects), Female, Humans, Male, Mental Status Schedule, Middle Aged, Motor Skills Disorders (etiology), Motor Skills Disorders (therapy), Parkinson Disease (pathology), Parkinson Disease (therapy), Personality, Quality of Life, Social Behavior, Substance-Related Disorders, Subthalamic Nucleus (physiology), Treatment Outcome.
MESH :
- adverse effects : Electric Stimulation Therapy.
- etiology : Anxiety, Depression, Motor Skills Disorders.
- pathology : Parkinson Disease.
- physiology : Subthalamic Nucleus.
- therapy : Motor Skills Disorders, Parkinson Disease.
- Female, Humans, Male, Mental Status Schedule, Middle Aged, Personality, Quality of Life, Social Behavior, Substance-Related Disorders, Treatment Outcome.

Abstract

Objective: to analyse 24 parkinsonian patients successfully treated by bilateral STN stimulation for the presence of behavioural disorders.

Method: patients were evaluated retrospectively for adjustment disorders (social adjustment scale, SAS), psychiatric disorders (comparison of the results of psychiatric interview and the mini international neuropsychiatric inventory) and personality changes (IOWA scale of personality changes).

Results: parkinsonian motor disability was improved by 69.5% and the levodopa equivalent daily dosage was reduced by 60.5%. Social adjustment (SAS) was considered good or excellent in nine patients, moderately (n=14), or severely (n=1) impaired in 15 patients. Psychiatric disorders consisted of amplification or decompensation of previously existing disorders that had sometimes passed unnoticed, such as depressive episodes (n=4), generalised anxiety (n=18), and behavioural disorders with drug dependence (n=2). Appearance of mild to moderate emotional hyperreactivity was reported in 15 patients. Personality traits (IOWA scale) were improved in eight patients, unchanged in seven, and aggravated in eight

Conclusion: Improvement in parkinsonian motor disability induced by STN stimulation is not necessarily accompanied by improvement in psychic function and quality of life. Attention is drawn to the possible appearance of personality disorders and decompensation of previous psychiatric disorders in parkinsonian patients who are suitable candidates for neurosurgery. We suggest that a careful psychological and psychiatric interview be performed before surgery, and emphasise the need for psychological follow up to ensure the best possible outcome.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1737905

DOI: 10.1136/jnnp.72.6.701
PubMed: 12023409
PubMed Central: 1737905

Affiliations:

Links to Exploration step

PMC:1737905

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Behavioural disorders, Parkinson's disease and subthalamic stimulation</title>
<author><name sortKey="Houeto, J" sort="Houeto, J" uniqKey="Houeto J" first="J" last="Houeto">J. Houeto</name>
</author>
<author><name sortKey="Mesnage, V" sort="Mesnage, V" uniqKey="Mesnage V" first="V" last="Mesnage">V. Mesnage</name>
</author>
<author><name sortKey="Mallet, L" sort="Mallet, L" uniqKey="Mallet L" first="L" last="Mallet">L. Mallet</name>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B" last="Pillon">B. Pillon</name>
</author>
<author><name sortKey="Gargiulo, M" sort="Gargiulo, M" uniqKey="Gargiulo M" first="M" last="Gargiulo">M. Gargiulo</name>
</author>
<author><name sortKey="Du Moncel, S T" sort="Du Moncel, S T" uniqKey="Du Moncel S" first="S T." last="Du Moncel">S T. Du Moncel</name>
</author>
<author><name sortKey="Bonnet, A" sort="Bonnet, A" uniqKey="Bonnet A" first="A" last="Bonnet">A. Bonnet</name>
</author>
<author><name sortKey="Pidoux, B" sort="Pidoux, B" uniqKey="Pidoux B" first="B" last="Pidoux">B. Pidoux</name>
</author>
<author><name sortKey="Dormont, D" sort="Dormont, D" uniqKey="Dormont D" first="D" last="Dormont">D. Dormont</name>
</author>
<author><name sortKey="Cornu, P" sort="Cornu, P" uniqKey="Cornu P" first="P" last="Cornu">P. Cornu</name>
</author>
<author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y" last="Agid">Yves Agid</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Paris</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
<orgName type="hospital" n="4">Hôpital de la Salpêtrière</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">12023409</idno>
<idno type="pmc">1737905</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1737905</idno>
<idno type="RBID">PMC:1737905</idno>
<idno type="doi">10.1136/jnnp.72.6.701</idno>
<date when="2002">2002</date>
<idno type="wicri:Area/Pmc/Corpus">000493</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000493</idno>
<idno type="wicri:Area/Pmc/Curation">000490</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000490</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000933</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000933</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">001187</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001187</idno>
<idno type="wicri:Area/PubMed/Curation">001146</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001146</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001146</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001146</idno>
<idno type="wicri:Area/Ncbi/Merge">000247</idno>
<idno type="wicri:Area/Ncbi/Curation">000247</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000247</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Behavioural disorders, Parkinson's disease and subthalamic stimulation</title>
<author><name sortKey="Houeto, J" sort="Houeto, J" uniqKey="Houeto J" first="J" last="Houeto">J. Houeto</name>
</author>
<author><name sortKey="Mesnage, V" sort="Mesnage, V" uniqKey="Mesnage V" first="V" last="Mesnage">V. Mesnage</name>
</author>
<author><name sortKey="Mallet, L" sort="Mallet, L" uniqKey="Mallet L" first="L" last="Mallet">L. Mallet</name>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B" last="Pillon">B. Pillon</name>
</author>
<author><name sortKey="Gargiulo, M" sort="Gargiulo, M" uniqKey="Gargiulo M" first="M" last="Gargiulo">M. Gargiulo</name>
</author>
<author><name sortKey="Du Moncel, S T" sort="Du Moncel, S T" uniqKey="Du Moncel S" first="S T." last="Du Moncel">S T. Du Moncel</name>
</author>
<author><name sortKey="Bonnet, A" sort="Bonnet, A" uniqKey="Bonnet A" first="A" last="Bonnet">A. Bonnet</name>
</author>
<author><name sortKey="Pidoux, B" sort="Pidoux, B" uniqKey="Pidoux B" first="B" last="Pidoux">B. Pidoux</name>
</author>
<author><name sortKey="Dormont, D" sort="Dormont, D" uniqKey="Dormont D" first="D" last="Dormont">D. Dormont</name>
</author>
<author><name sortKey="Cornu, P" sort="Cornu, P" uniqKey="Cornu P" first="P" last="Cornu">P. Cornu</name>
</author>
<author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y" last="Agid">Yves Agid</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Paris</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
<orgName type="hospital" n="4">Hôpital de la Salpêtrière</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Neurology, Neurosurgery, and Psychiatry</title>
<idno type="ISSN">0022-3050</idno>
<idno type="eISSN">1468-330X</idno>
<imprint><date when="2002">2002</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anxiety (etiology)</term>
<term>Depression (etiology)</term>
<term>Electric Stimulation Therapy (adverse effects)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Mental Status Schedule</term>
<term>Middle Aged</term>
<term>Motor Skills Disorders (etiology)</term>
<term>Motor Skills Disorders (therapy)</term>
<term>Parkinson Disease (pathology)</term>
<term>Parkinson Disease (therapy)</term>
<term>Personality</term>
<term>Quality of Life</term>
<term>Social Behavior</term>
<term>Substance-Related Disorders</term>
<term>Subthalamic Nucleus (physiology)</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Electric Stimulation Therapy</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Anxiety</term>
<term>Depression</term>
<term>Motor Skills Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Subthalamic Nucleus</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Motor Skills Disorders</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Mental Status Schedule</term>
<term>Middle Aged</term>
<term>Personality</term>
<term>Quality of Life</term>
<term>Social Behavior</term>
<term>Substance-Related Disorders</term>
<term>Treatment Outcome</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><bold>Objective:</bold>
 to analyse 24 parkinsonian patients successfully treated by bilateral STN stimulation for the presence of behavioural disorders. </p>
<p><bold>Method:</bold>
 patients were evaluated retrospectively for adjustment disorders (social adjustment scale, SAS), psychiatric disorders (comparison of the results of psychiatric interview and the mini international neuropsychiatric inventory) and personality changes (IOWA scale of personality changes). </p>
<p><bold>Results:</bold>
 parkinsonian motor disability was improved by 69.5% and the levodopa equivalent daily dosage was reduced by 60.5%. Social adjustment (SAS) was considered good or excellent in nine patients, moderately (n=14), or severely (n=1) impaired in 15 patients. Psychiatric disorders consisted of amplification or decompensation of previously existing disorders that had sometimes passed unnoticed, such as depressive episodes (n=4), generalised anxiety (n=18), and behavioural disorders with drug dependence (n=2). Appearance of mild to moderate emotional hyperreactivity was reported in 15 patients. Personality traits (IOWA scale) were improved in eight patients, unchanged in seven, and aggravated in eight </p>
<p><bold>Conclusion:</bold>
 Improvement in parkinsonian motor disability induced by STN stimulation is not necessarily accompanied by improvement in psychic function and quality of life. Attention is drawn to the possible appearance of personality disorders and decompensation of previous psychiatric disorders in parkinsonian patients who are suitable candidates for neurosurgery. We suggest that a careful psychological and psychiatric interview be performed before surgery, and emphasise the need for psychological follow up to ensure the best possible outcome. </p>
</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<region><li>Île-de-France</li>
</region>
<settlement><li>Paris</li>
</settlement>
<orgName><li>Hôpital de la Salpêtrière</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Bonnet, A" sort="Bonnet, A" uniqKey="Bonnet A" first="A" last="Bonnet">A. Bonnet</name>
<name sortKey="Cornu, P" sort="Cornu, P" uniqKey="Cornu P" first="P" last="Cornu">P. Cornu</name>
<name sortKey="Dormont, D" sort="Dormont, D" uniqKey="Dormont D" first="D" last="Dormont">D. Dormont</name>
<name sortKey="Du Moncel, S T" sort="Du Moncel, S T" uniqKey="Du Moncel S" first="S T." last="Du Moncel">S T. Du Moncel</name>
<name sortKey="Gargiulo, M" sort="Gargiulo, M" uniqKey="Gargiulo M" first="M" last="Gargiulo">M. Gargiulo</name>
<name sortKey="Houeto, J" sort="Houeto, J" uniqKey="Houeto J" first="J" last="Houeto">J. Houeto</name>
<name sortKey="Mallet, L" sort="Mallet, L" uniqKey="Mallet L" first="L" last="Mallet">L. Mallet</name>
<name sortKey="Mesnage, V" sort="Mesnage, V" uniqKey="Mesnage V" first="V" last="Mesnage">V. Mesnage</name>
<name sortKey="Pidoux, B" sort="Pidoux, B" uniqKey="Pidoux B" first="B" last="Pidoux">B. Pidoux</name>
<name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B" last="Pillon">B. Pillon</name>
</noCountry>
<country name="France"><region name="Île-de-France"><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y" last="Agid">Yves Agid</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Ncbi/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000247 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 000247 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    ParkinsonFranceV1
   |flux=    Ncbi
   |étape=   Checkpoint
   |type=    RBID
   |clé=     PMC:1737905
   |texte=   Behavioural disorders, Parkinson's disease and subthalamic stimulation
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i   -Sk "pubmed:12023409" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a ParkinsonFranceV1

This area was generated with Dilib version V0.6.29.
Data generation: Wed May 17 19:46:39 2017. Site generation: Mon Mar 4 15:48:15 2024

La maladie de Parkinson en France (serveur d'exploration)

Behavioural disorders, Parkinson's disease and subthalamic stimulation

Behavioural disorders, Parkinson's disease and subthalamic stimulation

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.