La maladie de Parkinson en France (serveur d'exploration)

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Behavioural disorders, Parkinson's disease and subthalamic stimulation.

Identifieur interne : 001187 ( PubMed/Corpus ); précédent : 001186; suivant : 001188

Behavioural disorders, Parkinson's disease and subthalamic stimulation.

Auteurs : J L Houeto ; V. Mesnage ; L. Mallet ; B. Pillon ; M. Gargiulo ; S Tezenas Du Moncel ; A M Bonnet ; B. Pidoux ; D. Dormont ; P. Cornu ; Y. Agid

Source :

RBID : pubmed:12023409

English descriptors

Abstract

to analyse 24 parkinsonian patients successfully treated by bilateral STN stimulation for the presence of behavioural disorders.

PubMed: 12023409

Links to Exploration step

pubmed:12023409

Le document en format XML

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<term>Motor Skills Disorders (therapy)</term>
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<div type="abstract" xml:lang="en">to analyse 24 parkinsonian patients successfully treated by bilateral STN stimulation for the presence of behavioural disorders.</div>
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<Month>Jun</Month>
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<Title>Journal of neurology, neurosurgery, and psychiatry</Title>
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<ArticleTitle>Behavioural disorders, Parkinson's disease and subthalamic stimulation.</ArticleTitle>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">to analyse 24 parkinsonian patients successfully treated by bilateral STN stimulation for the presence of behavioural disorders.</AbstractText>
<AbstractText Label="METHOD" NlmCategory="METHODS">patients were evaluated retrospectively for adjustment disorders (social adjustment scale, SAS), psychiatric disorders (comparison of the results of psychiatric interview and the mini international neuropsychiatric inventory) and personality changes (IOWA scale of personality changes).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">parkinsonian motor disability was improved by 69.5% and the levodopa equivalent daily dosage was reduced by 60.5%. Social adjustment (SAS) was considered good or excellent in nine patients, moderately (n=14), or severely (n=1) impaired in 15 patients. Psychiatric disorders consisted of amplification or decompensation of previously existing disorders that had sometimes passed unnoticed, such as depressive episodes (n=4), generalised anxiety (n=18), and behavioural disorders with drug dependence (n=2). Appearance of mild to moderate emotional hyperreactivity was reported in 15 patients. Personality traits (IOWA scale) were improved in eight patients, unchanged in seven, and aggravated in eight</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Improvement in parkinsonian motor disability induced by STN stimulation is not necessarily accompanied by improvement in psychic function and quality of life. Attention is drawn to the possible appearance of personality disorders and decompensation of previous psychiatric disorders in parkinsonian patients who are suitable candidates for neurosurgery. We suggest that a careful psychological and psychiatric interview be performed before surgery, and emphasise the need for psychological follow up to ensure the best possible outcome.</AbstractText>
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