Treatment of motor dysfunction in Parkinson's disease: an overview
Identifieur interne : 003109 ( Main/Merge ); précédent : 003108; suivant : 003110Treatment of motor dysfunction in Parkinson's disease: an overview
Auteurs : Stéphane Thobois [France] ; Florence Delamarre-Damier [France] ; Pascal Derkinderen [France]Source :
- Clinical neurology and neurosurgery [ 0303-8467 ] ; 2005.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Chirurgie.
English descriptors
Abstract
Levodopa remains the most effective treatment for Parkinson's disease (PD). However, the use of this drug is complicated by several adverse effects, in particular motor fluctuations and dyskinesias. Drugs providing more continuous dopaminergic stimulation and surgical approaches, such as deep-brain stimulation, have an important ameliorative effect on these problems. Despite these advances, the progression of the disease remains unaffected and strategies that slow or stop the neurodegenerative process are currently not available. Nevertheless, several compounds or surgical procedures are candidates for being neuroprotective and some of them are under evaluation.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000C89
- to stream PascalFrancis, to step Curation: 000745
- to stream PascalFrancis, to step Checkpoint: 000A86
Links to Exploration step
Pascal:05-0254276Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Treatment of motor dysfunction in Parkinson's disease: an overview</title>
<author><name sortKey="Thobois, Stephane" sort="Thobois, Stephane" uniqKey="Thobois S" first="Stéphane" last="Thobois">Stéphane Thobois</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Service de Neurologie, Hôpital Neurologique Pierre Wertheimer</s1>
<s2>Lyon</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Delamarre Damier, Florence" sort="Delamarre Damier, Florence" uniqKey="Delamarre Damier F" first="Florence" last="Delamarre-Damier">Florence Delamarre-Damier</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>ITG, Consulting Group</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Derkinderen, Pascal" sort="Derkinderen, Pascal" uniqKey="Derkinderen P" first="Pascal" last="Derkinderen">Pascal Derkinderen</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Service de Neurologie et Centre d'investigations cliniques, CHU de Nantes, Hôpital Laennec</s1>
<s2>Nantes</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Pays de la Loire</region>
<region type="old region">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">05-0254276</idno>
<date when="2005">2005</date>
<idno type="stanalyst">PASCAL 05-0254276 INIST</idno>
<idno type="RBID">Pascal:05-0254276</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000C89</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000745</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000A86</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000A86</idno>
<idno type="wicri:doubleKey">0303-8467:2005:Thobois S:treatment:of:motor</idno>
<idno type="wicri:Area/Main/Merge">003109</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Treatment of motor dysfunction in Parkinson's disease: an overview</title>
<author><name sortKey="Thobois, Stephane" sort="Thobois, Stephane" uniqKey="Thobois S" first="Stéphane" last="Thobois">Stéphane Thobois</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Service de Neurologie, Hôpital Neurologique Pierre Wertheimer</s1>
<s2>Lyon</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Delamarre Damier, Florence" sort="Delamarre Damier, Florence" uniqKey="Delamarre Damier F" first="Florence" last="Delamarre-Damier">Florence Delamarre-Damier</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>ITG, Consulting Group</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Derkinderen, Pascal" sort="Derkinderen, Pascal" uniqKey="Derkinderen P" first="Pascal" last="Derkinderen">Pascal Derkinderen</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Service de Neurologie et Centre d'investigations cliniques, CHU de Nantes, Hôpital Laennec</s1>
<s2>Nantes</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Pays de la Loire</region>
<region type="old region">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Clinical neurology and neurosurgery</title>
<title level="j" type="abbreviated">Clin. neurol. neurosurg.</title>
<idno type="ISSN">0303-8467</idno>
<imprint><date when="2005">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Clinical neurology and neurosurgery</title>
<title level="j" type="abbreviated">Clin. neurol. neurosurg.</title>
<idno type="ISSN">0303-8467</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Dopamine agonist</term>
<term>Levodopa</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
<term>Surgery</term>
<term>Treatment</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Chirurgie</term>
<term>Traitement</term>
<term>Parkinson maladie</term>
<term>Lévodopa</term>
<term>Stimulant dopaminergique</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Levodopa remains the most effective treatment for Parkinson's disease (PD). However, the use of this drug is complicated by several adverse effects, in particular motor fluctuations and dyskinesias. Drugs providing more continuous dopaminergic stimulation and surgical approaches, such as deep-brain stimulation, have an important ameliorative effect on these problems. Despite these advances, the progression of the disease remains unaffected and strategies that slow or stop the neurodegenerative process are currently not available. Nevertheless, several compounds or surgical procedures are candidates for being neuroprotective and some of them are under evaluation.</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<region><li>Auvergne-Rhône-Alpes</li>
<li>Pays de la Loire</li>
<li>Rhône-Alpes</li>
<li>Île-de-France</li>
</region>
<settlement><li>Lyon</li>
<li>Nantes</li>
<li>Paris</li>
</settlement>
</list>
<tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Thobois, Stephane" sort="Thobois, Stephane" uniqKey="Thobois S" first="Stéphane" last="Thobois">Stéphane Thobois</name>
</region>
<name sortKey="Delamarre Damier, Florence" sort="Delamarre Damier, Florence" uniqKey="Delamarre Damier F" first="Florence" last="Delamarre-Damier">Florence Delamarre-Damier</name>
<name sortKey="Derkinderen, Pascal" sort="Derkinderen, Pascal" uniqKey="Derkinderen P" first="Pascal" last="Derkinderen">Pascal Derkinderen</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003109 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 003109 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonFranceV1 |flux= Main |étape= Merge |type= RBID |clé= Pascal:05-0254276 |texte= Treatment of motor dysfunction in Parkinson's disease: an overview }}
![]() | This area was generated with Dilib version V0.6.29. | ![]() |