Qualitative and Quantitative Multiplexed Proteomic Analysis of Complex Yeast Protein Fractions That Modulate the Assembly of the Yeast Prion Sup35p
Identifieur interne : 001618 ( Main/Merge ); précédent : 001617; suivant : 001619Qualitative and Quantitative Multiplexed Proteomic Analysis of Complex Yeast Protein Fractions That Modulate the Assembly of the Yeast Prion Sup35p
Auteurs : Virginie Redeker [France] ; Chris Hughes [Royaume-Uni] ; Jimmy Savistchenko [France] ; Johannes P. C. Vissers [Royaume-Uni] ; Ronald Melki [France]Source :
- PLoS ONE [ 1932-6203 ] ; 2011.
Abstract
The aggregation of the baker's yeast prion Sup35p is at the origin of the transmissible [
We designed a functional proteomic study that combines two techniques to identify modulators of Sup35p aggregation and describe the changes associated to [
Our functional proteomic study provides the first inventory list of over 300 proteins that directly or indirectly affect Sup35p aggregation and [
Url:
DOI: 10.1371/journal.pone.0023659
PubMed: 21931608
PubMed Central: 3172207
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PMC:3172207Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Qualitative and Quantitative Multiplexed Proteomic Analysis of Complex Yeast Protein Fractions That Modulate the Assembly of the Yeast Prion Sup35p</title><author><name sortKey="Redeker, Virginie" sort="Redeker, Virginie" uniqKey="Redeker V" first="Virginie" last="Redeker">Virginie Redeker</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Gif-sur-Yvette</settlement></placeName></affiliation></author><author><name sortKey="Hughes, Chris" sort="Hughes, Chris" uniqKey="Hughes C" first="Chris" last="Hughes">Chris Hughes</name><affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Waters Corporation, Atlas Park, Manchester, United Kingdom</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Waters Corporation, Atlas Park, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Savistchenko, Jimmy" sort="Savistchenko, Jimmy" uniqKey="Savistchenko J" first="Jimmy" last="Savistchenko">Jimmy Savistchenko</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Gif-sur-Yvette</settlement></placeName></affiliation></author><author><name sortKey="Vissers, Johannes P C" sort="Vissers, Johannes P C" uniqKey="Vissers J" first="Johannes P. 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Vissers</name><affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Waters Corporation, Atlas Park, Manchester, United Kingdom</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Waters Corporation, Atlas Park, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Melki, Ronald" sort="Melki, Ronald" uniqKey="Melki R" first="Ronald" last="Melki">Ronald Melki</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Gif-sur-Yvette</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21931608</idno><idno type="pmc">3172207</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172207</idno><idno type="RBID">PMC:3172207</idno><idno type="doi">10.1371/journal.pone.0023659</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">000860</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000860</idno><idno type="wicri:Area/Pmc/Curation">000857</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000857</idno><idno type="wicri:Area/Pmc/Checkpoint">000667</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000667</idno><idno type="wicri:Area/Ncbi/Merge">000D82</idno><idno type="wicri:Area/Ncbi/Curation">000D82</idno><idno type="wicri:Area/Ncbi/Checkpoint">000D82</idno><idno type="wicri:Area/Main/Merge">001618</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Qualitative and Quantitative Multiplexed Proteomic Analysis of Complex Yeast Protein Fractions That Modulate the Assembly of the Yeast Prion Sup35p</title><author><name sortKey="Redeker, Virginie" sort="Redeker, Virginie" uniqKey="Redeker V" first="Virginie" last="Redeker">Virginie Redeker</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Gif-sur-Yvette</settlement></placeName></affiliation></author><author><name sortKey="Hughes, Chris" sort="Hughes, Chris" uniqKey="Hughes C" first="Chris" last="Hughes">Chris Hughes</name><affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Waters Corporation, Atlas Park, Manchester, United Kingdom</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Waters Corporation, Atlas Park, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Savistchenko, Jimmy" sort="Savistchenko, Jimmy" uniqKey="Savistchenko J" first="Jimmy" last="Savistchenko">Jimmy Savistchenko</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Gif-sur-Yvette</settlement></placeName></affiliation></author><author><name sortKey="Vissers, Johannes P C" sort="Vissers, Johannes P C" uniqKey="Vissers J" first="Johannes P. C." last="Vissers">Johannes P. C. Vissers</name><affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Waters Corporation, Atlas Park, Manchester, United Kingdom</addr-line></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Waters Corporation, Atlas Park, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Melki, Ronald" sort="Melki, Ronald" uniqKey="Melki R" first="Ronald" last="Melki">Ronald Melki</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Gif-sur-Yvette</settlement></placeName></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>The aggregation of the baker's yeast prion Sup35p is at the origin of the transmissible [<italic>PSI<sup>+</sup></italic>] trait. We and others have shown that molecular chaperones modulate Sup35p aggregation. However, other protein classes might be involved in [<italic>PSI<sup>+</sup></italic>] formation.</p></sec><sec><title>Results</title><p>We designed a functional proteomic study that combines two techniques to identify modulators of Sup35p aggregation and describe the changes associated to [<italic>PSI<sup>+</sup></italic>] formation. The first allows measuring the effect of fractionated <italic>Saccharomyces cerevisiae</italic> cytosolic extracts from [<italic>PSI<sup>+</sup></italic>] and [<italic>psi<sup>−</sup></italic>] yeast cells on Sup35p assembly. The second is a multiplex qualitative and quantitative comparison of protein composition of active and inactive fractions using a gel-free and label-free LC-MS approach. We identify changes in proteins involved in translation, folding, degradation, oxido-reduction and metabolic processes.</p></sec><sec><title>Conclusion</title><p>Our functional proteomic study provides the first inventory list of over 300 proteins that directly or indirectly affect Sup35p aggregation and [<italic>PSI<sup>+</sup></italic>] formation. Our results highlight the complexity of the cellular changes accompanying [<italic>PSI<sup>+</sup></italic>] formation and pave the way for <italic>in vitro</italic> studies aimed to document the effect of individual and/or combinations of proteins identified here, susceptible of affecting Sup35p assembly.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Prusiner, Sb" uniqKey="Prusiner S">SB Prusiner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brundin, P" uniqKey="Brundin P">P Brundin</name></author><author><name sortKey="Melki, R" uniqKey="Melki R">R Melki</name></author><author><name sortKey="Kopito, R" uniqKey="Kopito R">R Kopito</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Castilla, J" uniqKey="Castilla J">J Castilla</name></author><author><name sortKey="Saa, P" uniqKey="Saa P">P Saá</name></author><author><name sortKey="Morales, R" uniqKey="Morales R">R Morales</name></author><author><name sortKey="Abid, K" uniqKey="Abid K">K Abid</name></author><author><name sortKey="Maundrell, K" uniqKey="Maundrell K">K Maundrell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tuite, Mf" uniqKey="Tuite M">MF Tuite</name></author><author><name sortKey="Cox, Bs" uniqKey="Cox B">BS Cox</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thual, C" uniqKey="Thual C">C Thual</name></author><author><name sortKey="Komar, Aa" uniqKey="Komar A">AA Komar</name></author><author><name sortKey="Bousset, L" uniqKey="Bousset L">L Bousset</name></author><author><name sortKey="Fernandez Bellot, E" uniqKey="Fernandez Bellot E">E Fernandez-Bellot</name></author><author><name sortKey="Cullin, C" uniqKey="Cullin C">C Cullin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Glover, Jr" uniqKey="Glover J">JR Glover</name></author><author><name sortKey="Kowal, As" uniqKey="Kowal A">AS Kowal</name></author><author><name sortKey="Schirmer, Ec" uniqKey="Schirmer E">EC Schirmer</name></author><author><name sortKey="Patino, Mm" uniqKey="Patino M">MM Patino</name></author><author><name sortKey="Liu, Jj" uniqKey="Liu J">JJ Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krzewska, J" uniqKey="Krzewska J">J Krzewska</name></author><author><name sortKey="Tanaka, M" uniqKey="Tanaka M">M Tanaka</name></author><author><name sortKey="Burston, Sg" uniqKey="Burston S">SG Burston</name></author><author><name sortKey="Melki, R" uniqKey="Melki R">R Melki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Patel, Bk" uniqKey="Patel B">BK Patel</name></author><author><name sortKey="Liebman, Sw" uniqKey="Liebman S">SW Liebman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paushkin, Sv" uniqKey="Paushkin S">SV Paushkin</name></author><author><name sortKey="Kushnirov, Vv" uniqKey="Kushnirov V">VV Kushnirov</name></author><author><name sortKey="Smirnov, Vn" uniqKey="Smirnov V">VN Smirnov</name></author><author><name sortKey="Ter Avanesyan, Md" uniqKey="Ter Avanesyan M">MD Ter-Avanesyan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cox, Bs" uniqKey="Cox B">BS Cox</name></author><author><name sortKey="Tuite, Mf" uniqKey="Tuite M">MF Tuite</name></author><author><name sortKey="Mclaughlin, Cs" uniqKey="Mclaughlin C">CS McLaughlin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krzewska, J" uniqKey="Krzewska J">J Krzewska</name></author><author><name sortKey="Melki, R" uniqKey="Melki R">R Melki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cottrell, Ba" uniqKey="Cottrell B">BA Cottrell</name></author><author><name sortKey="Galvan, V" uniqKey="Galvan V">V Galvan</name></author><author><name sortKey="Banwait, S" uniqKey="Banwait S">S Banwait</name></author><author><name sortKey="Gorostiza, O" uniqKey="Gorostiza O">O Gorostiza</name></author><author><name sortKey="Lombardo, Cr" uniqKey="Lombardo C">CR Lombardo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mitsui, K" uniqKey="Mitsui K">K Mitsui</name></author><author><name sortKey="Doi, H" uniqKey="Doi H">H Doi</name></author><author><name sortKey="Nukina, N" uniqKey="Nukina N">N Nukina</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schonberger, Sj" uniqKey="Schonberger S">SJ Schonberger</name></author><author><name sortKey="Edgar, Pf" uniqKey="Edgar P">PF Edgar</name></author><author><name sortKey="Kydd, R" uniqKey="Kydd R">R Kydd</name></author><author><name sortKey="Faull, Rl" uniqKey="Faull R">RL Faull</name></author><author><name sortKey="Cooper, Gj" uniqKey="Cooper G">GJ Cooper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sorolla, Ma" uniqKey="Sorolla M">MA Sorolla</name></author><author><name sortKey="Reverter Branchat, G" uniqKey="Reverter Branchat G">G Reverter-Branchat</name></author><author><name sortKey="Tamarit, J" uniqKey="Tamarit J">J Tamarit</name></author><author><name sortKey="Ferrer, I" uniqKey="Ferrer I">I Ferrer</name></author><author><name sortKey="Ros, J" uniqKey="Ros J">J Ros</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Iuliis, A" uniqKey="De Iuliis A">A De Iuliis</name></author><author><name sortKey="Grigoletto, J" uniqKey="Grigoletto J">J Grigoletto</name></author><author><name sortKey="Recchia, A" uniqKey="Recchia A">A Recchia</name></author><author><name sortKey="Giusti, P" uniqKey="Giusti P">P Giusti</name></author><author><name sortKey="Arslan, P" uniqKey="Arslan P">P Arslan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chich, Jf" uniqKey="Chich J">JF Chich</name></author><author><name sortKey="Schaeffer, B" uniqKey="Schaeffer B">B Schaeffer</name></author><author><name sortKey="Bouin, Ap" uniqKey="Bouin A">AP Bouin</name></author><author><name sortKey="Mouthon, F" uniqKey="Mouthon F">F Mouthon</name></author><author><name sortKey="Labas, V" uniqKey="Labas V">V Labas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xun, Z" uniqKey="Xun Z">Z Xun</name></author><author><name sortKey="Sowell, Ra" uniqKey="Sowell R">RA Sowell</name></author><author><name sortKey="Kaufman, Tc" uniqKey="Kaufman T">TC Kaufman</name></author><author><name sortKey="Clemmer, De" uniqKey="Clemmer D">DE Clemmer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Simpson, Kl" uniqKey="Simpson K">KL Simpson</name></author><author><name sortKey="Whetton, Ad" uniqKey="Whetton A">AD Whetton</name></author><author><name sortKey="Dive, C" uniqKey="Dive C">C Dive</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gygi, Sp" uniqKey="Gygi S">SP Gygi</name></author><author><name sortKey="Rist, B" uniqKey="Rist B">B Rist</name></author><author><name sortKey="Gerber, Sa" uniqKey="Gerber S">SA Gerber</name></author><author><name sortKey="Turecek, F" uniqKey="Turecek F">F Turecek</name></author><author><name sortKey="Gelb, Mh" uniqKey="Gelb M">MH Gelb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ross, Pl" uniqKey="Ross P">PL Ross</name></author><author><name sortKey="Huang, Yn" uniqKey="Huang Y">YN Huang</name></author><author><name sortKey="Marchese, Jn" uniqKey="Marchese J">JN Marchese</name></author><author><name sortKey="Williamson, B" uniqKey="Williamson B">B Williamson</name></author><author><name sortKey="Parker, K" uniqKey="Parker K">K Parker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Washburn, Mp" uniqKey="Washburn M">MP Washburn</name></author><author><name sortKey="Wolters, D" uniqKey="Wolters D">D Wolters</name></author><author><name sortKey="Yates, Jr" uniqKey="Yates J">JR Yates</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nesvizhskii, Ai" uniqKey="Nesvizhskii A">AI Nesvizhskii</name></author><author><name sortKey="Vitek, O" uniqKey="Vitek O">O Vitek</name></author><author><name sortKey="Aebersold, R" uniqKey="Aebersold R">R Aebersold</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Old, Wm" uniqKey="Old W">WM Old</name></author><author><name sortKey="Meyer Arendt, K" uniqKey="Meyer Arendt K">K Meyer-Arendt</name></author><author><name sortKey="Aveline Wolf, L" uniqKey="Aveline Wolf L">L Aveline-Wolf</name></author><author><name sortKey="Pierce, Kg" uniqKey="Pierce K">KG Pierce</name></author><author><name sortKey="Mendoza, A" uniqKey="Mendoza A">A Mendoza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silva, Jc" uniqKey="Silva J">JC Silva</name></author><author><name sortKey="Denny, R" uniqKey="Denny R">R Denny</name></author><author><name sortKey="Dorschel, Ca" uniqKey="Dorschel C">CA Dorschel</name></author><author><name sortKey="Gorenstein, M" uniqKey="Gorenstein M">M Gorenstein</name></author><author><name sortKey="Kass, Ij" uniqKey="Kass I">IJ Kass</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vissers, Jp" uniqKey="Vissers J">JP Vissers</name></author><author><name sortKey="Pons, S" uniqKey="Pons S">S Pons</name></author><author><name sortKey="Hulin, A" uniqKey="Hulin A">A Hulin</name></author><author><name sortKey="Tissier, R" uniqKey="Tissier R">R Tissier</name></author><author><name sortKey="Berdeaux, A" uniqKey="Berdeaux A">A Berdeaux</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silva, Jc" uniqKey="Silva J">JC Silva</name></author><author><name sortKey="Gorenstein, Mv" uniqKey="Gorenstein M">MV Gorenstein</name></author><author><name sortKey="Li, Gz" uniqKey="Li G">GZ Li</name></author><author><name sortKey="Vissers, Jp" uniqKey="Vissers J">JP Vissers</name></author><author><name sortKey="Geromanos, Sj" uniqKey="Geromanos S">SJ Geromanos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcparland, Vj" uniqKey="Mcparland V">VJ McParland</name></author><author><name sortKey="Kad, Nm" uniqKey="Kad N">NM Kad</name></author><author><name sortKey="Kalverda, Ap" uniqKey="Kalverda A">AP Kalverda</name></author><author><name sortKey="Brown, A" uniqKey="Brown A">A Brown</name></author><author><name sortKey="Kirwin Jones, P" uniqKey="Kirwin Jones P">P Kirwin-Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bradford, Mm" uniqKey="Bradford M">MM Bradford</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, Yq" uniqKey="Yu Y">YQ Yu</name></author><author><name sortKey="Gilar, M" uniqKey="Gilar M">M Gilar</name></author><author><name sortKey="Lee, Pj" uniqKey="Lee P">PJ Lee</name></author><author><name sortKey="Bouvier, Es" uniqKey="Bouvier E">ES Bouvier</name></author><author><name sortKey="Gebler, Jc" uniqKey="Gebler J">JC Gebler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Gz" uniqKey="Li G">GZ Li</name></author><author><name sortKey="Vissers, Jp" uniqKey="Vissers J">JP Vissers</name></author><author><name sortKey="Silva, Jc" uniqKey="Silva J">JC Silva</name></author><author><name sortKey="Golick, D" uniqKey="Golick D">D Golick</name></author><author><name sortKey="Gorenstein, Mv" uniqKey="Gorenstein M">MV Gorenstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Geromanos, Sj" uniqKey="Geromanos S">SJ Geromanos</name></author><author><name sortKey="Vissers, Jp" uniqKey="Vissers J">JP Vissers</name></author><author><name sortKey="Silva, Jc" uniqKey="Silva J">JC Silva</name></author><author><name sortKey="Dorschel, Ca" uniqKey="Dorschel C">CA Dorschel</name></author><author><name sortKey="Li, Gz" uniqKey="Li G">GZ Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silva, Jc" uniqKey="Silva J">JC Silva</name></author><author><name sortKey="Denny, R" uniqKey="Denny R">R Denny</name></author><author><name sortKey="Dorschel, C" uniqKey="Dorschel C">C Dorschel</name></author><author><name sortKey="Gorenstein, Mv" uniqKey="Gorenstein M">MV Gorenstein</name></author><author><name sortKey="Li, Gz" uniqKey="Li G">GZ Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peisker, K" uniqKey="Peisker K">K Peisker</name></author><author><name sortKey="Braun, D" uniqKey="Braun D">D Braun</name></author><author><name sortKey="Wolfle, T" uniqKey="Wolfle T">T Wölfle</name></author><author><name sortKey="Hentschel, J" uniqKey="Hentschel J">J Hentschel</name></author><author><name sortKey="Funfschilling, U" uniqKey="Funfschilling U">U Fünfschilling</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shorter, J" uniqKey="Shorter J">J Shorter</name></author><author><name sortKey="Lindquist, S" uniqKey="Lindquist S">S Lindquist</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bukau, B" uniqKey="Bukau B">B Bukau</name></author><author><name sortKey="Weissman, J" uniqKey="Weissman J">J Weissman</name></author><author><name sortKey="Horwich, A" uniqKey="Horwich A">A Horwich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, P" uniqKey="Huang P">P Huang</name></author><author><name sortKey="Gautschi, M" uniqKey="Gautschi M">M Gautschi</name></author><author><name sortKey="Walter, W" uniqKey="Walter W">W Walter</name></author><author><name sortKey="Rospert, S" uniqKey="Rospert S">S Rospert</name></author><author><name sortKey="Craig, Ea" uniqKey="Craig E">EA Craig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Voges, D" uniqKey="Voges D">D Voges</name></author><author><name sortKey="Zwickl, P" uniqKey="Zwickl P">P Zwickl</name></author><author><name sortKey="Baumeister, W" uniqKey="Baumeister W">W Baumeister</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Groll, M" uniqKey="Groll M">M Groll</name></author><author><name sortKey="Ditzel, L" uniqKey="Ditzel L">L Ditzel</name></author><author><name sortKey="Lowe, J" uniqKey="Lowe J">J Löwe</name></author><author><name sortKey="Stock, D" uniqKey="Stock D">D Stock</name></author><author><name sortKey="Bochtler, M" uniqKey="Bochtler M">M Bochtler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Singh, R" uniqKey="Singh R">R Singh</name></author><author><name sortKey="Rao, Chm" uniqKey="Rao C">ChM Rao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Basu, A" uniqKey="Basu A">A Basu</name></author><author><name sortKey="Samanta, D" uniqKey="Samanta D">D Samanta</name></author><author><name sortKey="Bhattacharya, A" uniqKey="Bhattacharya A">A Bhattacharya</name></author><author><name sortKey="Das, A" uniqKey="Das A">A Das</name></author><author><name sortKey="Das, D" uniqKey="Das D">D Das</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Basu, A" uniqKey="Basu A">A Basu</name></author><author><name sortKey="Samanta, D" uniqKey="Samanta D">D Samanta</name></author><author><name sortKey="Das, D" uniqKey="Das D">D Das</name></author><author><name sortKey="Chowdhury, S" uniqKey="Chowdhury S">S Chowdhury</name></author><author><name sortKey="Bhattacharya, A" uniqKey="Bhattacharya A">A Bhattacharya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tribouillard Tanvier, D" uniqKey="Tribouillard Tanvier D">D Tribouillard-Tanvier</name></author><author><name sortKey="Dos Reis, S" uniqKey="Dos Reis S">S Dos Reis</name></author><author><name sortKey="Gug, F" uniqKey="Gug F">F Gug</name></author><author><name sortKey="Voisset, C" uniqKey="Voisset C">C Voisset</name></author><author><name sortKey="Beringue, V" uniqKey="Beringue V">V Béringue</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cosson, B" uniqKey="Cosson B">B Cosson</name></author><author><name sortKey="Couturier, A" uniqKey="Couturier A">A Couturier</name></author><author><name sortKey="Chabelskaya, S" uniqKey="Chabelskaya S">S Chabelskaya</name></author><author><name sortKey="Kiktev, D" uniqKey="Kiktev D">D Kiktev</name></author><author><name sortKey="Inge Vechtomov, S" uniqKey="Inge Vechtomov S">S Inge-Vechtomov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, Gw" uniqKey="Jones G">GW Jones</name></author><author><name sortKey="Masison, Dc" uniqKey="Masison D">DC Masison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, Gw" uniqKey="Jones G">GW Jones</name></author><author><name sortKey="Tuite, Mf" uniqKey="Tuite M">MF Tuite</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chernoff, Yo" uniqKey="Chernoff Y">YO Chernoff</name></author><author><name sortKey="Lindquist, Sl" uniqKey="Lindquist S">SL Lindquist</name></author><author><name sortKey="Ono, B" uniqKey="Ono B">B Ono</name></author><author><name sortKey="Inge Vechtomov, Sg" uniqKey="Inge Vechtomov S">SG Inge-Vechtomov</name></author><author><name sortKey="Liebman, Sw" uniqKey="Liebman S">SW Liebman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chernoff, Yo" uniqKey="Chernoff Y">YO Chernoff</name></author><author><name sortKey="Newnam, Gp" uniqKey="Newnam G">GP Newnam</name></author><author><name sortKey="Kumar, J" uniqKey="Kumar J">J Kumar</name></author><author><name sortKey="Allen, K" uniqKey="Allen K">K Allen</name></author><author><name sortKey="Zink, Ad" uniqKey="Zink A">AD Zink</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kushnirov, Vv" uniqKey="Kushnirov V">VV Kushnirov</name></author><author><name sortKey="Kryndushkin, Ds" uniqKey="Kryndushkin D">DS Kryndushkin</name></author><author><name sortKey="Boguta, M" uniqKey="Boguta M">M Boguta</name></author><author><name sortKey="Smirnov, Vn" uniqKey="Smirnov V">VN Smirnov</name></author><author><name sortKey="Ter Avanesyan, Md" uniqKey="Ter Avanesyan M">MD Ter-Avanesyan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sharma, D" uniqKey="Sharma D">D Sharma</name></author><author><name sortKey="Martineau, Cn" uniqKey="Martineau C">CN Martineau</name></author><author><name sortKey="Le Dall, Mt" uniqKey="Le Dall M">MT Le Dall</name></author><author><name sortKey="Reidy, M" uniqKey="Reidy M">M Reidy</name></author><author><name sortKey="Masison, Dc" uniqKey="Masison D">DC Masison</name></author></analytic></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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