Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.
Identifieur interne : 000165 ( Main/Exploration ); précédent : 000164; suivant : 000166Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.
Auteurs : Michel Engeln [France] ; Matthieu F. Bastide [France] ; Estelle Toulmé [France] ; Benjamin Dehay [France] ; Mathieu Bourdenx [France] ; Evelyne Doudnikoff [France] ; Qin Li [République populaire de Chine] ; Christian E. Gross [France] ; Eric Boué-Grabot [France] ; Antonio Pisani [Italie] ; Erwan Bezard [France] ; Pierre-Olivier Fernagut [France]Source :
- Biological psychiatry [ 1873-2402 ] ; 2016.
English descriptors
- KwdEn :
- Animals, Antiparkinson Agents (adverse effects), Daunorubicin (administration & dosage), Daunorubicin (analogs & derivatives), Disease Models, Animal, Dyskinesia, Drug-Induced (drug therapy), Levodopa (adverse effects), Macaca fascicularis, Male, Neostriatum (drug effects), Neurons (drug effects), Oxidopamine (administration & dosage), Parkinson Disease (complications), Patch-Clamp Techniques, Proto-Oncogene Proteins c-fos (metabolism), Rats, Rats, Sprague-Dawley, Receptors, Dopamine D1 (metabolism).
- MESH :
- chemical , administration & dosage : Daunorubicin, Oxidopamine.
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- chemical , analogs & derivatives : Daunorubicin.
- complications : Parkinson Disease.
- drug effects : Neostriatum, Neurons.
- drug therapy : Dyskinesia, Drug-Induced.
- chemical , metabolism : Proto-Oncogene Proteins c-fos, Receptors, Dopamine D1.
- Animals, Disease Models, Animal, Macaca fascicularis, Male, Patch-Clamp Techniques, Rats, Rats, Sprague-Dawley.
Abstract
ΔFosB is a surrogate marker of L-DOPA-induced dyskinesia (LID), the unavoidable disabling consequence of Parkinson's disease L-DOPA long-term treatment. However, the relationship between the electrical activity of FosB/ΔFosB-expressing neurons and LID manifestation is unknown.
DOI: 10.1016/j.biopsych.2014.07.007
PubMed: 25146322
Affiliations:
- France, Italie, République populaire de Chine
- Aquitaine, Latium, Nouvelle-Aquitaine
- Bordeaux, Pékin, Rome
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Le document en format XML
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Bastide</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Toulme, Estelle" sort="Toulme, Estelle" uniqKey="Toulme E" first="Estelle" last="Toulmé">Estelle Toulmé</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Dehay, Benjamin" sort="Dehay, Benjamin" uniqKey="Dehay B" first="Benjamin" last="Dehay">Benjamin Dehay</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Bourdenx, Mathieu" sort="Bourdenx, Mathieu" uniqKey="Bourdenx M" first="Mathieu" last="Bourdenx">Mathieu Bourdenx</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Doudnikoff, Evelyne" sort="Doudnikoff, Evelyne" uniqKey="Doudnikoff E" first="Evelyne" last="Doudnikoff">Evelyne Doudnikoff</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Li, Qin" sort="Li, Qin" uniqKey="Li Q" first="Qin" last="Li">Qin Li</name><affiliation wicri:level="3"><nlm:affiliation>China Academy of Medical Sciences, Institute of Laboratory Animal Sciences, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>China Academy of Medical Sciences, Institute of Laboratory Animal Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Gross, Christian E" sort="Gross, Christian E" uniqKey="Gross C" first="Christian E" last="Gross">Christian E. Gross</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Boue Grabot, Eric" sort="Boue Grabot, Eric" uniqKey="Boue Grabot E" first="Eric" last="Boué-Grabot">Eric Boué-Grabot</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Pisani, Antonio" sort="Pisani, Antonio" uniqKey="Pisani A" first="Antonio" last="Pisani">Antonio Pisani</name><affiliation wicri:level="3"><nlm:affiliation>Laboratory of Neurophysiology and Plasticity, Fondazione Santa Lucia, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Neurophysiology and Plasticity, Fondazione Santa Lucia, Istituto di Ricovero e Cura a Carattere Scientifico, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Bezard, Erwan" sort="Bezard, Erwan" uniqKey="Bezard E" first="Erwan" last="Bezard">Erwan Bezard</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Fernagut, Pierre Olivier" sort="Fernagut, Pierre Olivier" uniqKey="Fernagut P" first="Pierre-Olivier" last="Fernagut">Pierre-Olivier Fernagut</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France. 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Bastide</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Toulme, Estelle" sort="Toulme, Estelle" uniqKey="Toulme E" first="Estelle" last="Toulmé">Estelle Toulmé</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Dehay, Benjamin" sort="Dehay, Benjamin" uniqKey="Dehay B" first="Benjamin" last="Dehay">Benjamin Dehay</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Bourdenx, Mathieu" sort="Bourdenx, Mathieu" uniqKey="Bourdenx M" first="Mathieu" last="Bourdenx">Mathieu Bourdenx</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Doudnikoff, Evelyne" sort="Doudnikoff, Evelyne" uniqKey="Doudnikoff E" first="Evelyne" last="Doudnikoff">Evelyne Doudnikoff</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Li, Qin" sort="Li, Qin" uniqKey="Li Q" first="Qin" last="Li">Qin Li</name><affiliation wicri:level="3"><nlm:affiliation>China Academy of Medical Sciences, Institute of Laboratory Animal Sciences, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>China Academy of Medical Sciences, Institute of Laboratory Animal Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Gross, Christian E" sort="Gross, Christian E" uniqKey="Gross C" first="Christian E" last="Gross">Christian E. Gross</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Boue Grabot, Eric" sort="Boue Grabot, Eric" uniqKey="Boue Grabot E" first="Eric" last="Boué-Grabot">Eric Boué-Grabot</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Pisani, Antonio" sort="Pisani, Antonio" uniqKey="Pisani A" first="Antonio" last="Pisani">Antonio Pisani</name><affiliation wicri:level="3"><nlm:affiliation>Laboratory of Neurophysiology and Plasticity, Fondazione Santa Lucia, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Neurophysiology and Plasticity, Fondazione Santa Lucia, Istituto di Ricovero e Cura a Carattere Scientifico, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Bezard, Erwan" sort="Bezard, Erwan" uniqKey="Bezard E" first="Erwan" last="Bezard">Erwan Bezard</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Fernagut, Pierre Olivier" sort="Fernagut, Pierre Olivier" uniqKey="Fernagut P" first="Pierre-Olivier" last="Fernagut">Pierre-Olivier Fernagut</name><affiliation wicri:level="3"><nlm:affiliation>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux, France. Electronic address: pierre-olivier.fernagut@u-bordeaux.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University de Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France; National Centre for Scientific Research, Institut des Maladies Neurodégénératives, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author></analytic><series><title level="j">Biological psychiatry</title><idno type="eISSN">1873-2402</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antiparkinson Agents (adverse effects)</term><term>Daunorubicin (administration & dosage)</term><term>Daunorubicin (analogs & derivatives)</term><term>Disease Models, Animal</term><term>Dyskinesia, Drug-Induced (drug therapy)</term><term>Levodopa (adverse effects)</term><term>Macaca fascicularis</term><term>Male</term><term>Neostriatum (drug effects)</term><term>Neurons (drug effects)</term><term>Oxidopamine (administration & dosage)</term><term>Parkinson Disease (complications)</term><term>Patch-Clamp Techniques</term><term>Proto-Oncogene Proteins c-fos (metabolism)</term><term>Rats</term><term>Rats, Sprague-Dawley</term><term>Receptors, Dopamine D1 (metabolism)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Daunorubicin</term><term>Oxidopamine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antiparkinson Agents</term><term>Levodopa</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Daunorubicin</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Neostriatum</term><term>Neurons</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Dyskinesia, Drug-Induced</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Proto-Oncogene Proteins c-fos</term><term>Receptors, Dopamine D1</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Models, Animal</term><term>Macaca fascicularis</term><term>Male</term><term>Patch-Clamp Techniques</term><term>Rats</term><term>Rats, Sprague-Dawley</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">ΔFosB is a surrogate marker of L-DOPA-induced dyskinesia (LID), the unavoidable disabling consequence of Parkinson's disease L-DOPA long-term treatment. However, the relationship between the electrical activity of FosB/ΔFosB-expressing neurons and LID manifestation is unknown.</div></front></TEI><affiliations><list><country><li>France</li><li>Italie</li><li>République populaire de Chine</li></country><region><li>Aquitaine</li><li>Latium</li><li>Nouvelle-Aquitaine</li></region><settlement><li>Bordeaux</li><li>Pékin</li><li>Rome</li></settlement></list><tree><country name="France"><region name="Nouvelle-Aquitaine"><name sortKey="Engeln, Michel" sort="Engeln, Michel" uniqKey="Engeln M" first="Michel" last="Engeln">Michel Engeln</name></region><name sortKey="Bastide, Matthieu F" sort="Bastide, Matthieu F" uniqKey="Bastide M" first="Matthieu F" last="Bastide">Matthieu F. Bastide</name><name sortKey="Bezard, Erwan" sort="Bezard, Erwan" uniqKey="Bezard E" first="Erwan" last="Bezard">Erwan Bezard</name><name sortKey="Boue Grabot, Eric" sort="Boue Grabot, Eric" uniqKey="Boue Grabot E" first="Eric" last="Boué-Grabot">Eric Boué-Grabot</name><name sortKey="Bourdenx, Mathieu" sort="Bourdenx, Mathieu" uniqKey="Bourdenx M" first="Mathieu" last="Bourdenx">Mathieu Bourdenx</name><name sortKey="Dehay, Benjamin" sort="Dehay, Benjamin" uniqKey="Dehay B" first="Benjamin" last="Dehay">Benjamin Dehay</name><name sortKey="Doudnikoff, Evelyne" sort="Doudnikoff, Evelyne" uniqKey="Doudnikoff E" first="Evelyne" last="Doudnikoff">Evelyne Doudnikoff</name><name sortKey="Fernagut, Pierre Olivier" sort="Fernagut, Pierre Olivier" uniqKey="Fernagut P" first="Pierre-Olivier" last="Fernagut">Pierre-Olivier Fernagut</name><name sortKey="Gross, Christian E" sort="Gross, Christian E" uniqKey="Gross C" first="Christian E" last="Gross">Christian E. Gross</name><name sortKey="Toulme, Estelle" sort="Toulme, Estelle" uniqKey="Toulme E" first="Estelle" last="Toulmé">Estelle Toulmé</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Li, Qin" sort="Li, Qin" uniqKey="Li Q" first="Qin" last="Li">Qin Li</name></noRegion></country><country name="Italie"><region name="Latium"><name sortKey="Pisani, Antonio" sort="Pisani, Antonio" uniqKey="Pisani A" first="Antonio" last="Pisani">Antonio Pisani</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.
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