ParkinsonFranceV1, Main, Exploration, bibRecordById, pubmed:14652103

Motor preparation is more impaired in Parkinson's disease when sensorimotor integration is involved

Identifieur interne : 003247 ( Main/Exploration ); précédent : 003246; suivant : 003248

Motor preparation is more impaired in Parkinson's disease when sensorimotor integration is involved

Auteurs : E. Labyt [France] ; D. Devos [France] ; J.-L. Bourriez [France] ; F. Cassim [France] ; A. Destee [France] ; J.-D. Guieu [France] ; L. Defebvre [France] ; P. Derambure [France]

Source :

Clinical neurophysiology [ 1388-2457 ] ; 2003.

RBID : Pascal:04-0259458

Descripteurs français

Pascal (Inist)
- Préparation motrice, Coordination sensorimotrice, Synchronisation, Performance, Mouvement corporel, Doigt, Extension, Contrôle moteur, Désynchronisation, Contrôle visuomoteur, Parkinson maladie, Electrodiagnostic, Topographie, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Body movement, Cortical Synchronization, Desynchronization, Dyskinesias (physiopathology), Electrodiagnosis, Electromyography, Extension, Female, Finger, Fingers, Functional Laterality, Human, Humans, Male, Middle Aged, Motor Neurons (physiology), Motor control, Motor preparation, Movement, Neurons, Afferent (physiology), Parkinson Disease (physiopathology), Parkinson disease, Performance, Psychomotor Performance (physiology), Sensorimotor coordination, Synchronization, Topography, Visuomotor control, Volition.
MESH :
- physiology : Motor Neurons, Neurons, Afferent, Psychomotor Performance.
- physiopathology : Dyskinesias, Parkinson Disease.
- Adult, Aged, Aged, 80 and over, Cortical Synchronization, Electromyography, Female, Fingers, Functional Laterality, Humans, Male, Middle Aged, Movement, Volition.

Abstract

Objective: This study aimed to investigate changes in spatio-temporal, event-related (de)synchronization (ERD/ERS) patterns recorded with respect to the more akinetic versus the less akinetic side during performance of a visuo-guided targeting movement when compared to an index finger extension. Methods: Twelve de novo parkinsonian patients were recorded. ERD/ERS in mu and beta frequency bands was computed from 21 source derivations. Results: When the index finger extension was performed with the less akinetic limb, mu ERD focused over contralateral central region appeared 2 s before movement. With the targeting movement, additional pre-movement mu ERD was observed over the parietal region, as well as earlier ipsilateral mu ERD. When the same movements were performed with the more akinetic limb, we observed delayed mu ERD over contralateral regions, earlier ipsilateral mu ERD and a lack of contralateral parietal mu ERD before the targeting movement. Following index finger extension for the less akinetic limb, a focused contralateral central beta ERS was recorded, increasing and spreading after the targeting movement. In contrast, for the more akinetic limb, beta ERS was dramatically attenuated and remained unchanged after the targeting movement. Conclusions: These results confirm the fact that motor programming is delayed, and provide some insight into what may well be impaired sensorimotor integration in Parkinson's disease.

Affiliations:

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Body movement</term>
<term>Cortical Synchronization</term>
<term>Desynchronization</term>
<term>Dyskinesias (physiopathology)</term>
<term>Electrodiagnosis</term>
<term>Electromyography</term>
<term>Extension</term>
<term>Female</term>
<term>Finger</term>
<term>Fingers</term>
<term>Functional Laterality</term>
<term>Human</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Motor Neurons (physiology)</term>
<term>Motor control</term>
<term>Motor preparation</term>
<term>Movement</term>
<term>Neurons, Afferent (physiology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson disease</term>
<term>Performance</term>
<term>Psychomotor Performance (physiology)</term>
<term>Sensorimotor coordination</term>
<term>Synchronization</term>
<term>Topography</term>
<term>Visuomotor control</term>
<term>Volition</term>
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<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Motor Neurons</term>
<term>Neurons, Afferent</term>
<term>Psychomotor Performance</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dyskinesias</term>
<term>Parkinson Disease</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Cortical Synchronization</term>
<term>Electromyography</term>
<term>Female</term>
<term>Fingers</term>
<term>Functional Laterality</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Movement</term>
<term>Volition</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Préparation motrice</term>
<term>Coordination sensorimotrice</term>
<term>Synchronisation</term>
<term>Performance</term>
<term>Mouvement corporel</term>
<term>Doigt</term>
<term>Extension</term>
<term>Contrôle moteur</term>
<term>Désynchronisation</term>
<term>Contrôle visuomoteur</term>
<term>Parkinson maladie</term>
<term>Electrodiagnostic</term>
<term>Topographie</term>
<term>Homme</term>
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<front><div type="abstract" xml:lang="en">Objective: This study aimed to investigate changes in spatio-temporal, event-related (de)synchronization (ERD/ERS) patterns recorded with respect to the more akinetic versus the less akinetic side during performance of a visuo-guided targeting movement when compared to an index finger extension. Methods: Twelve de novo parkinsonian patients were recorded. ERD/ERS in mu and beta frequency bands was computed from 21 source derivations. Results: When the index finger extension was performed with the less akinetic limb, mu ERD focused over contralateral central region appeared 2 s before movement. With the targeting movement, additional pre-movement mu ERD was observed over the parietal region, as well as earlier ipsilateral mu ERD. When the same movements were performed with the more akinetic limb, we observed delayed mu ERD over contralateral regions, earlier ipsilateral mu ERD and a lack of contralateral parietal mu ERD before the targeting movement. Following index finger extension for the less akinetic limb, a focused contralateral central beta ERS was recorded, increasing and spreading after the targeting movement. In contrast, for the more akinetic limb, beta ERS was dramatically attenuated and remained unchanged after the targeting movement. Conclusions: These results confirm the fact that motor programming is delayed, and provide some insight into what may well be impaired sensorimotor integration in Parkinson's disease.</div>
</front>
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<name sortKey="Bourriez, J L" sort="Bourriez, J L" uniqKey="Bourriez J" first="J.-L." last="Bourriez">J.-L. Bourriez</name>
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<name sortKey="Guieu, J D" sort="Guieu, J D" uniqKey="Guieu J" first="J.-D." last="Guieu">J.-D. Guieu</name>
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   |clé=     Pascal:04-0259458
   |texte=   Motor preparation is more impaired in Parkinson's disease when sensorimotor integration is involved
}}

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La maladie de Parkinson en France (serveur d'exploration)

Motor preparation is more impaired in Parkinson's disease when sensorimotor integration is involved

Motor preparation is more impaired in Parkinson's disease when sensorimotor integration is involved

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	La maladie de Parkinson en France (serveur d'exploration)
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