La maladie de Parkinson en France (serveur d'exploration)

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Left Ventricular Diastolic Dysfunction in Patients with So‐Called Lone Atrial Fibrillation

Identifieur interne : 003A18 ( Main/Exploration ); précédent : 003A17; suivant : 003A19

Left Ventricular Diastolic Dysfunction in Patients with So‐Called Lone Atrial Fibrillation

Auteurs : Pierre Jaïs [États-Unis] ; Jing Tian Peng [États-Unis] ; Dipen C. Shah [États-Unis] ; Stéphane Garrfgue [États-Unis] ; Mélèze Hocini [États-Unis] ; Teiichi Yamane [États-Unis] ; Michel Haissaguerre [États-Unis] ; Serge S. Barold [États-Unis] ; Raymond Roudaut [États-Unis] ; Jacques Clementy [États-Unis]

Source :

RBID : ISTEX:69F7E8820F91CF8430705005237276DF567ECD37

English descriptors

Abstract

LV Diastolic Dysfunction in Lone AF. Lone atrial fibrillation (AF) is defined by the absence of identifiable causes of AF, but its hemodynamics have not been investigated. Twenty‐eight patients with lone AF were compared with 14 control patients referred for for Woff‐Parkinson‐White ablation. Transthoracic and transesophageal echocardiography were performed to rule out structural heart disease, followed by transseptally performed complete hemodynamic evaluation of the left heart systolic and diastolic function. There was no evidence of diastolic dysfunction according to echocardiographic criteria in AF and control patients. There was no difference in echocardiographic measurements, except for a significantly higher inferosuperior left atrial dimension seen in the four‐chamber apical view in AF patients (51 ± 10 vs 40 ± 6 mm, P = 0.03). Hemodynamic evaluation showed that end‐diastolic left ventricular pressure and the nadir of the left atrial Y descent were significantly higher in lone AF patients versus controls: 13 ± 5 versus 8 ± 3 mmHg (P = 0.001) and 6.7 ± 3 versus 4.6 ± 2.7 mmHg (P = 0.05). Our results demonstrated the presence of diastolic left heart dysfunction in patients with so‐called lone AF.

Url:
DOI: 10.1111/j.1540-8167.2000.tb00023.x


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">LV Diastolic Dysfunction in Lone AF. Lone atrial fibrillation (AF) is defined by the absence of identifiable causes of AF, but its hemodynamics have not been investigated. Twenty‐eight patients with lone AF were compared with 14 control patients referred for for Woff‐Parkinson‐White ablation. Transthoracic and transesophageal echocardiography were performed to rule out structural heart disease, followed by transseptally performed complete hemodynamic evaluation of the left heart systolic and diastolic function. There was no evidence of diastolic dysfunction according to echocardiographic criteria in AF and control patients. There was no difference in echocardiographic measurements, except for a significantly higher inferosuperior left atrial dimension seen in the four‐chamber apical view in AF patients (51 ± 10 vs 40 ± 6 mm, P = 0.03). Hemodynamic evaluation showed that end‐diastolic left ventricular pressure and the nadir of the left atrial Y descent were significantly higher in lone AF patients versus controls: 13 ± 5 versus 8 ± 3 mmHg (P = 0.001) and 6.7 ± 3 versus 4.6 ± 2.7 mmHg (P = 0.05). Our results demonstrated the presence of diastolic left heart dysfunction in patients with so‐called lone AF.</div>
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