La maladie de Parkinson en France (serveur d'exploration)

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Multiorgan aluminium deposits in a chronic haemodialysis patient

Identifieur interne : 005587 ( Main/Exploration ); précédent : 005586; suivant : 005588

Multiorgan aluminium deposits in a chronic haemodialysis patient

Auteurs : A. Roth [France] ; C. Nogues [France] ; P. Galle ; T. Drüeke

Source :

RBID : ISTEX:1CDB3110DBC6E2BCC89458FD3668C41795897DBA

Abstract

Summary: The study reports an aluminium-intoxicated haemodialysis patient who had encephalopathy, osteomalacia and congestive cardiomyopathy prior to his death. Detailed light and electron microscope examination revealed the presence of aluminium deposits within lysosomes of cells from many organs, including the kidney, liver, brain and heart. The heavy aluminium deposits in myocardial lysosomes favor a possible role of the trace element in the patient's congestive cardiomyopathy.

Url:
DOI: 10.1007/BF00694931


Affiliations:


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<div type="abstract" xml:lang="en">Summary: The study reports an aluminium-intoxicated haemodialysis patient who had encephalopathy, osteomalacia and congestive cardiomyopathy prior to his death. Detailed light and electron microscope examination revealed the presence of aluminium deposits within lysosomes of cells from many organs, including the kidney, liver, brain and heart. The heavy aluminium deposits in myocardial lysosomes favor a possible role of the trace element in the patient's congestive cardiomyopathy.</div>
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