Multiorgan aluminium deposits in a chronic haemodialysis patient
Identifieur interne : 000833 ( Istex/Curation ); précédent : 000832; suivant : 000834Multiorgan aluminium deposits in a chronic haemodialysis patient
Auteurs : A. Roth [France] ; C. Nogues [France] ; P. Galle ; T. DrüekeSource :
- Virchows Archiv A [ 0174-7398 ] ; 1984-03-01.
Abstract
Summary: The study reports an aluminium-intoxicated haemodialysis patient who had encephalopathy, osteomalacia and congestive cardiomyopathy prior to his death. Detailed light and electron microscope examination revealed the presence of aluminium deposits within lysosomes of cells from many organs, including the kidney, liver, brain and heart. The heavy aluminium deposits in myocardial lysosomes favor a possible role of the trace element in the patient's congestive cardiomyopathy.
Url:
DOI: 10.1007/BF00694931
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P. Galle<affiliation><mods:affiliation>Département de Biophysique, Hôpital Henri Mondor, Créteil</mods:affiliation>
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<affiliation><mods:affiliation>Département de Néphrologie et INSERM U 90, Hôpital Necker-Enfants Malades, F-75743, Paris Cedex</mods:affiliation>
<wicri:noCountry code="subField">Cedex</wicri:noCountry>
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<front><div type="abstract" xml:lang="en">Summary: The study reports an aluminium-intoxicated haemodialysis patient who had encephalopathy, osteomalacia and congestive cardiomyopathy prior to his death. Detailed light and electron microscope examination revealed the presence of aluminium deposits within lysosomes of cells from many organs, including the kidney, liver, brain and heart. The heavy aluminium deposits in myocardial lysosomes favor a possible role of the trace element in the patient's congestive cardiomyopathy.</div>
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