Failure of long-term pallidal stimulation corrected by subthalamic stimulation in PD
Identifieur interne : 003B90 ( Main/Exploration ); précédent : 003B89; suivant : 003B91Failure of long-term pallidal stimulation corrected by subthalamic stimulation in PD
Auteurs : J. L. Houeto [France] ; P. B. Bejjani [France] ; P. Damier [France] ; C. Staedler [France] ; A. M. Bonnet [France] ; B. Pidoux [France] ; D. Dormont [France] ; P. Cornu [France] ; Yves Agid [Liban]Source :
- Neurology [ 0028-3878 ] ; 2000.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Bilateral, Case study, Electric Stimulation, Female, Globus Pallidus (pathology), Globus Pallidus (physiopathology), High frequency, Human, Humans, Instrumental stimulation, Magnetic Resonance Imaging, Male, Middle Aged, Pallidum, Parkinson Disease (pathology), Parkinson Disease (physiopathology), Parkinson Disease (therapy), Parkinson disease, Subthalamic Nucleus (physiopathology), Subthalamic nucleus, Time Factors, Treatment.
- MESH :
- pathology : Globus Pallidus, Parkinson Disease.
- physiopathology : Globus Pallidus, Parkinson Disease, Subthalamic Nucleus.
- therapy : Parkinson Disease.
- Electric Stimulation, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Time Factors.
Abstract
-Bilateral high-frequency continuous stimulation of the internal globus pallidus or subthalamic nucleus constitutes a new therapeutic approach for the treatment of patients with severe PD. The authors report two patients in whom stimulation of the globus pallidus failed to give long-term relief and was successfully replaced by bilateral subthalamic stimulation. The results emphasize the reversibility of deep brain stimulation therapy and suggest that the subthalamic target is preferable to the pallidal target.
Affiliations:
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Le document en format XML
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<term>Globus Pallidus (physiopathology)</term>
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<term>Humans</term>
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<front><div type="abstract" xml:lang="en">-Bilateral high-frequency continuous stimulation of the internal globus pallidus or subthalamic nucleus constitutes a new therapeutic approach for the treatment of patients with severe PD. The authors report two patients in whom stimulation of the globus pallidus failed to give long-term relief and was successfully replaced by bilateral subthalamic stimulation. The results emphasize the reversibility of deep brain stimulation therapy and suggest that the subthalamic target is preferable to the pallidal target.</div>
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