ParkinsonFranceV1, Main, Exploration, bibRecord, 003510

Intraoperative micro- and macrostimulation of the subthalamic nucleus in Parkinson's disease

Identifieur interne : 003510 ( Main/Exploration ); précédent : 003509; suivant : 003511

Intraoperative micro- and macrostimulation of the subthalamic nucleus in Parkinson's disease

Auteurs : Pierre Pollak [France] ; Paul Krack [France] ; Valérie Fraix [France] ; Alexandre Mendes [France] ; Elena Moro [France] ; Stephan Chabardes [France] ; Alim-Louis Benabid [France]

Source :

Movement disorders [ 0885-3185 ] ; 2002.

RBID : Pascal:02-0309292

Descripteurs français

Pascal (Inist)
- Parkinson maladie, Stimulation instrumentale, Noyau sousthalamique, Microélectrode, Traitement, Homme, Macroélectrode.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Brain Mapping (instrumentation), Brain Mapping (methods), Electric Stimulation Therapy, Human, Humans, Instrumental stimulation, Microelectrode, Microelectrodes, Monitoring, Intraoperative (instrumentation), Neurons (physiology), Parkinson Disease (physiopathology), Parkinson Disease (surgery), Parkinson Disease (therapy), Parkinson disease, Stereotaxic Techniques, Subthalamic Nucleus (physiopathology), Subthalamic Nucleus (surgery), Subthalamic nucleus, Treatment.
MESH :
- instrumentation : Brain Mapping, Monitoring, Intraoperative.
- methods : Brain Mapping.
- physiology : Neurons.
- physiopathology : Parkinson Disease, Subthalamic Nucleus.
- surgery : Parkinson Disease, Subthalamic Nucleus.
- therapy : Parkinson Disease.
- Electric Stimulation Therapy, Humans, Microelectrodes, Stereotaxic Techniques.

Abstract

Studying the clinical effects induced by electrical stimulation of the subthalamic nucleus (STN) area in a parkinsonian patient under local anesthesia is a mandatory step to determine the precise location of the final chronic electrode. Using multiple microelectrodes, preferably in a concentric parallel array allows a precise mapping of the STN region. The most reliable features to determine the suitable target are stimulation-induced dyskinesias and rigidity decrease at a low intensity without adverse effects or only at far higher intensities. New skills are needed to assess all stimulation-induced effects and interpret them in anatomo-functional terms.

Affiliations:

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Intraoperative micro- and macrostimulation of the subthalamic nucleus in Parkinson's disease</title>
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<placeName><region type="region">Auvergne-Rhône-Alpes</region>
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<settlement type="city">Grenoble</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Benabid, Alim Louis" sort="Benabid, Alim Louis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>INSERM Unit 318, Joseph Fourier University</s1>
<s2>Grenoble</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Grenoble</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Clinical and Biological Neurosciences, Service de Neurochirurgie, Centre Hospitalier Universitaire de Grenoble</s1>
<s2>Grenoble</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Grenoble</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2002">2002</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brain Mapping (instrumentation)</term>
<term>Brain Mapping (methods)</term>
<term>Electric Stimulation Therapy</term>
<term>Human</term>
<term>Humans</term>
<term>Instrumental stimulation</term>
<term>Microelectrode</term>
<term>Microelectrodes</term>
<term>Monitoring, Intraoperative (instrumentation)</term>
<term>Neurons (physiology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (surgery)</term>
<term>Parkinson Disease (therapy)</term>
<term>Parkinson disease</term>
<term>Stereotaxic Techniques</term>
<term>Subthalamic Nucleus (physiopathology)</term>
<term>Subthalamic Nucleus (surgery)</term>
<term>Subthalamic nucleus</term>
<term>Treatment</term>
</keywords>
<keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Brain Mapping</term>
<term>Monitoring, Intraoperative</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Brain Mapping</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Neurons</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term>
<term>Subthalamic Nucleus</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Parkinson Disease</term>
<term>Subthalamic Nucleus</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Electric Stimulation Therapy</term>
<term>Humans</term>
<term>Microelectrodes</term>
<term>Stereotaxic Techniques</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term>
<term>Stimulation instrumentale</term>
<term>Noyau sousthalamique</term>
<term>Microélectrode</term>
<term>Traitement</term>
<term>Homme</term>
<term>Macroélectrode</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Studying the clinical effects induced by electrical stimulation of the subthalamic nucleus (STN) area in a parkinsonian patient under local anesthesia is a mandatory step to determine the precise location of the final chronic electrode. Using multiple microelectrodes, preferably in a concentric parallel array allows a precise mapping of the STN region. The most reliable features to determine the suitable target are stimulation-induced dyskinesias and rigidity decrease at a low intensity without adverse effects or only at far higher intensities. New skills are needed to assess all stimulation-induced effects and interpret them in anatomo-functional terms.</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<region><li>Auvergne-Rhône-Alpes</li>
<li>Rhône-Alpes</li>
</region>
<settlement><li>Grenoble</li>
</settlement>
</list>
<tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
</region>
<name sortKey="Benabid, Alim Louis" sort="Benabid, Alim Louis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
<name sortKey="Benabid, Alim Louis" sort="Benabid, Alim Louis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
<name sortKey="Chabardes, Stephan" sort="Chabardes, Stephan" uniqKey="Chabardes S" first="Stephan" last="Chabardes">Stephan Chabardes</name>
<name sortKey="Chabardes, Stephan" sort="Chabardes, Stephan" uniqKey="Chabardes S" first="Stephan" last="Chabardes">Stephan Chabardes</name>
<name sortKey="Fraix, Valerie" sort="Fraix, Valerie" uniqKey="Fraix V" first="Valérie" last="Fraix">Valérie Fraix</name>
<name sortKey="Fraix, Valerie" sort="Fraix, Valerie" uniqKey="Fraix V" first="Valérie" last="Fraix">Valérie Fraix</name>
<name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name>
<name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name>
<name sortKey="Mendes, Alexandre" sort="Mendes, Alexandre" uniqKey="Mendes A" first="Alexandre" last="Mendes">Alexandre Mendes</name>
<name sortKey="Mendes, Alexandre" sort="Mendes, Alexandre" uniqKey="Mendes A" first="Alexandre" last="Mendes">Alexandre Mendes</name>
<name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name>
<name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name>
<name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
</country>
</tree>
</affiliations>
</record>

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La maladie de Parkinson en France (serveur d'exploration)

Intraoperative micro- and macrostimulation of the subthalamic nucleus in Parkinson's disease

Intraoperative micro- and macrostimulation of the subthalamic nucleus in Parkinson's disease

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	La maladie de Parkinson en France (serveur d'exploration)
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