Intraoperative micro- and macrostimulation of the subthalamic nucleus in Parkinson's disease.
Identifieur interne : 000238 ( Ncbi/Curation ); précédent : 000237; suivant : 000239Intraoperative micro- and macrostimulation of the subthalamic nucleus in Parkinson's disease.
Auteurs : Pierre Pollak [France] ; Paul Krack ; Valérie Fraix ; Alexandre Mendes ; Elena Moro ; Stephan Chabardes ; Alim-Louis BenabidSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2002.
English descriptors
- KwdEn :
- Brain Mapping (instrumentation), Brain Mapping (methods), Electric Stimulation Therapy, Humans, Microelectrodes, Monitoring, Intraoperative (instrumentation), Neurons (physiology), Parkinson Disease (physiopathology), Parkinson Disease (surgery), Parkinson Disease (therapy), Stereotaxic Techniques, Subthalamic Nucleus (physiopathology), Subthalamic Nucleus (surgery).
- MESH :
- instrumentation : Brain Mapping, Monitoring, Intraoperative.
- methods : Brain Mapping.
- physiology : Neurons.
- physiopathology : Parkinson Disease, Subthalamic Nucleus.
- surgery : Parkinson Disease, Subthalamic Nucleus.
- therapy : Parkinson Disease.
- Electric Stimulation Therapy, Humans, Microelectrodes, Stereotaxic Techniques.
Abstract
Studying the clinical effects induced by electrical stimulation of the subthalamic nucleus (STN) area in a parkinsonian patient under local anesthesia is a mandatory step to determine the precise location of the final chronic electrode. Using multiple microelectrodes, preferably in a concentric parallel array allows a precise mapping of the STN region. The most reliable features to determine the suitable target are stimulation-induced dyskinesias and rigidity decrease at a low intensity without adverse effects or only at far higher intensities. New skills are needed to assess all stimulation-induced effects and interpret them in anatomo-functional terms.
PubMed: 11948771
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pubmed:11948771Le document en format XML
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