Impact of deep brain stimulation on pharyngo-esophageal motility: a randomized cross-over study.
Identifieur interne : 000607 ( Main/Exploration ); précédent : 000606; suivant : 000608Impact of deep brain stimulation on pharyngo-esophageal motility: a randomized cross-over study.
Auteurs : S. Derrey [France] ; N. Chastan [France] ; D. Maltete [France] ; E. Verin [France] ; P. Dechelotte [France] ; R. Lefaucheur [France] ; F. Proust [France] ; P. Freger [France] ; A M Leroi [France] ; J. Weber [France] ; G. Gourcerol [France]Source :
- Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society [ 1365-2982 ] ; 2015.
English descriptors
- KwdEn :
- Aged, Cross-Over Studies, Deep Brain Stimulation, Esophagus (physiopathology), Female, Gastrointestinal Motility, Humans, Male, Manometry, Middle Aged, Parkinson Disease (physiopathology), Parkinson Disease (therapy), Pharynx (physiopathology), Subthalamic Nucleus (physiopathology), Treatment Outcome.
- MESH :
- physiopathology : Esophagus, Parkinson Disease, Pharynx, Subthalamic Nucleus.
- therapy : Parkinson Disease.
- Aged, Cross-Over Studies, Deep Brain Stimulation, Female, Gastrointestinal Motility, Humans, Male, Manometry, Middle Aged, Treatment Outcome.
Abstract
Bilateral subthalamic nucleus (STN) stimulation is used to alleviate Parkinson's disease (PD) motor symptoms. Recently, it has been shown that this therapeutic also increased gut cholinergic contractions. We therefore investigated the effect of STN stimulation on esophageal motility in an interventional randomized study.
DOI: 10.1111/nmo.12607
PubMed: 26053217
Affiliations:
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Derrey</name><affiliation wicri:level="3"><nlm:affiliation>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Chastan, N" sort="Chastan, N" uniqKey="Chastan N" first="N" last="Chastan">N. Chastan</name><affiliation wicri:level="3"><nlm:affiliation>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Maltete, D" sort="Maltete, D" uniqKey="Maltete D" first="D" last="Maltete">D. Maltete</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Rouen University Hospital, University of Rouen, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology, Rouen University Hospital, University of Rouen, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Verin, E" sort="Verin, E" uniqKey="Verin E" first="E" last="Verin">E. Verin</name><affiliation wicri:level="3"><nlm:affiliation>Department of Physiology, Rouen University Hospital, University of Rouen, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Physiology, Rouen University Hospital, University of Rouen, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Dechelotte, P" sort="Dechelotte, P" uniqKey="Dechelotte P" first="P" last="Dechelotte">P. Dechelotte</name><affiliation wicri:level="3"><nlm:affiliation>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Lefaucheur, R" sort="Lefaucheur, R" uniqKey="Lefaucheur R" first="R" last="Lefaucheur">R. Lefaucheur</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Rouen University Hospital, University of Rouen, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology, Rouen University Hospital, University of Rouen, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Proust, F" sort="Proust, F" uniqKey="Proust F" first="F" last="Proust">F. Proust</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurosurgery, Rouen University Hospital, University of Rouen, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurosurgery, Rouen University Hospital, University of Rouen, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Freger, P" sort="Freger, P" uniqKey="Freger P" first="P" last="Freger">P. Freger</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurosurgery, Rouen University Hospital, University of Rouen, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurosurgery, Rouen University Hospital, University of Rouen, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Leroi, A M" sort="Leroi, A M" uniqKey="Leroi A" first="A M" last="Leroi">A M Leroi</name><affiliation wicri:level="3"><nlm:affiliation>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Weber, J" sort="Weber, J" uniqKey="Weber J" first="J" last="Weber">J. Weber</name><affiliation wicri:level="3"><nlm:affiliation>Department of Physiology, Rouen University Hospital, University of Rouen, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Physiology, Rouen University Hospital, University of Rouen, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Gourcerol, G" sort="Gourcerol, G" uniqKey="Gourcerol G" first="G" last="Gourcerol">G. Gourcerol</name><affiliation wicri:level="3"><nlm:affiliation>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Nutrition, Gut & Brain Unit (INSERM UMR 1073), Institute for Biomedical Research and Innovation, Rouen University, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author></analytic><series><title level="j">Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society</title><idno type="eISSN">1365-2982</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Cross-Over Studies</term><term>Deep Brain Stimulation</term><term>Esophagus (physiopathology)</term><term>Female</term><term>Gastrointestinal Motility</term><term>Humans</term><term>Male</term><term>Manometry</term><term>Middle Aged</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (therapy)</term><term>Pharynx (physiopathology)</term><term>Subthalamic Nucleus (physiopathology)</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Esophagus</term><term>Parkinson Disease</term><term>Pharynx</term><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Cross-Over Studies</term><term>Deep Brain Stimulation</term><term>Female</term><term>Gastrointestinal Motility</term><term>Humans</term><term>Male</term><term>Manometry</term><term>Middle Aged</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Bilateral subthalamic nucleus (STN) stimulation is used to alleviate Parkinson's disease (PD) motor symptoms. Recently, it has been shown that this therapeutic also increased gut cholinergic contractions. We therefore investigated the effect of STN stimulation on esophageal motility in an interventional randomized study.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Haute-Normandie</li><li>Région Normandie</li></region><settlement><li>Rouen</li></settlement></list><tree><country name="France"><region name="Région Normandie"><name sortKey="Derrey, S" sort="Derrey, S" uniqKey="Derrey S" first="S" last="Derrey">S. Derrey</name></region><name sortKey="Chastan, N" sort="Chastan, N" uniqKey="Chastan N" first="N" last="Chastan">N. Chastan</name><name sortKey="Dechelotte, P" sort="Dechelotte, P" uniqKey="Dechelotte P" first="P" last="Dechelotte">P. Dechelotte</name><name sortKey="Freger, P" sort="Freger, P" uniqKey="Freger P" first="P" last="Freger">P. Freger</name><name sortKey="Gourcerol, G" sort="Gourcerol, G" uniqKey="Gourcerol G" first="G" last="Gourcerol">G. Gourcerol</name><name sortKey="Lefaucheur, R" sort="Lefaucheur, R" uniqKey="Lefaucheur R" first="R" last="Lefaucheur">R. Lefaucheur</name><name sortKey="Leroi, A M" sort="Leroi, A M" uniqKey="Leroi A" first="A M" last="Leroi">A M Leroi</name><name sortKey="Maltete, D" sort="Maltete, D" uniqKey="Maltete D" first="D" last="Maltete">D. Maltete</name><name sortKey="Proust, F" sort="Proust, F" uniqKey="Proust F" first="F" last="Proust">F. Proust</name><name sortKey="Verin, E" sort="Verin, E" uniqKey="Verin E" first="E" last="Verin">E. Verin</name><name sortKey="Weber, J" sort="Weber, J" uniqKey="Weber J" first="J" last="Weber">J. Weber</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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