Impact of deep brain stimulation on pharyngo-esophageal motility: a randomized cross-over study.
Identifieur interne : 001738 ( Ncbi/Curation ); précédent : 001737; suivant : 001739Impact of deep brain stimulation on pharyngo-esophageal motility: a randomized cross-over study.
Auteurs : S. Derrey [France] ; N. Chastan [France] ; D. Maltete [France] ; E. Verin [France] ; P. Dechelotte [France] ; R. Lefaucheur [France] ; F. Proust [France] ; P. Freger [France] ; A M Leroi [France] ; J. Weber [France] ; G. Gourcerol [France]Source :
- Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society [ 1365-2982 ] ; 2015.
English descriptors
- KwdEn :
- Aged, Cross-Over Studies, Deep Brain Stimulation, Esophagus (physiopathology), Female, Gastrointestinal Motility, Humans, Male, Manometry, Middle Aged, Parkinson Disease (physiopathology), Parkinson Disease (therapy), Pharynx (physiopathology), Subthalamic Nucleus (physiopathology), Treatment Outcome.
- MESH :
- physiopathology : Esophagus, Parkinson Disease, Pharynx, Subthalamic Nucleus.
- therapy : Parkinson Disease.
- Aged, Cross-Over Studies, Deep Brain Stimulation, Female, Gastrointestinal Motility, Humans, Male, Manometry, Middle Aged, Treatment Outcome.
Abstract
Bilateral subthalamic nucleus (STN) stimulation is used to alleviate Parkinson's disease (PD) motor symptoms. Recently, it has been shown that this therapeutic also increased gut cholinergic contractions. We therefore investigated the effect of STN stimulation on esophageal motility in an interventional randomized study.
DOI: 10.1111/nmo.12607
PubMed: 26053217
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<term>Cross-Over Studies</term>
<term>Deep Brain Stimulation</term>
<term>Esophagus (physiopathology)</term>
<term>Female</term>
<term>Gastrointestinal Motility</term>
<term>Humans</term>
<term>Male</term>
<term>Manometry</term>
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<term>Parkinson Disease (physiopathology)</term>
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<term>Deep Brain Stimulation</term>
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<front><div type="abstract" xml:lang="en">Bilateral subthalamic nucleus (STN) stimulation is used to alleviate Parkinson's disease (PD) motor symptoms. Recently, it has been shown that this therapeutic also increased gut cholinergic contractions. We therefore investigated the effect of STN stimulation on esophageal motility in an interventional randomized study.</div>
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