ParkinsonFranceV1, Main, Exploration, bibRecord, 000494

Survival, Differentiation, and Neuroprotective Mechanisms of Human Stem Cells Complexed With Neurotrophin-3-Releasing Pharmacologically Active Microcarriers in an Ex Vivo Model of Parkinson’s Disease

Identifieur interne : 000494 ( Main/Exploration ); précédent : 000493; suivant : 000495

Survival, Differentiation, and Neuroprotective Mechanisms of Human Stem Cells Complexed With Neurotrophin-3-Releasing Pharmacologically Active Microcarriers in an Ex Vivo Model of Parkinson’s Disease

Auteurs : Nicolas Daviaud ; Elisa Garbayo ; Laurence Sindji ; Alberto Martínez-Serrano ; Paul C. Schiller ; Claudia N. Montero-Menei

Source :

Stem Cells Translational Medicine [ 2157-6564 ] ; 2015.

RBID : PMC:4449089

English descriptors

mix :
- Laminin, Mesenchymal Stem Cells, Neural stem cells, Neurotrophin-3, Organotypic slice culture, Stanniocalcin-1, tissue engineering, vascular endothelial growth factor.

Abstract

The survival, differentiation, and neuroprotective mechanisms of marrow-isolated adult multilineage inducible (MIAMI) cells and neural stem cells (NSCs), both adhering to neurotrophin-3 releasing pharmacologically active microcarriers (PAMs) in an ex vivo organotypic model of nigrostriatal degeneration made from brain sagittal slices were elucidated. The results indicate a prospective interest of human NSC/PAM and MIAMI cell/PAM complexes in tissue engineering for Parkinson’s disease.

Url:

DOI: 10.5966/sctm.2014-0139
PubMed: 25925835
PubMed Central: 4449089

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>The survival, differentiation, and neuroprotective mechanisms of marrow-isolated adult multilineage inducible (MIAMI) cells and neural stem cells (NSCs), both adhering to neurotrophin-3 releasing pharmacologically active microcarriers (PAMs) in an ex vivo organotypic model of nigrostriatal degeneration made from brain sagittal slices were elucidated. The results indicate a prospective interest of human NSC/PAM and MIAMI cell/PAM complexes in tissue engineering for Parkinson’s disease.</p>
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<name sortKey="Martinez Serrano, Alberto" sort="Martinez Serrano, Alberto" uniqKey="Martinez Serrano A" first="Alberto" last="Martínez-Serrano">Alberto Martínez-Serrano</name>
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<name sortKey="Schiller, Paul C" sort="Schiller, Paul C" uniqKey="Schiller P" first="Paul C." last="Schiller">Paul C. Schiller</name>
<name sortKey="Sindji, Laurence" sort="Sindji, Laurence" uniqKey="Sindji L" first="Laurence" last="Sindji">Laurence Sindji</name>
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La maladie de Parkinson en France (serveur d'exploration)

Survival, Differentiation, and Neuroprotective Mechanisms of Human Stem Cells Complexed With Neurotrophin-3-Releasing Pharmacologically Active Microcarriers in an Ex Vivo Model of Parkinson’s Disease

Survival, Differentiation, and Neuroprotective Mechanisms of Human Stem Cells Complexed With Neurotrophin-3-Releasing Pharmacologically Active Microcarriers in an Ex Vivo Model of Parkinson’s Disease

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.