Subthalamic stimulation may inhibit the beneficial effects of levodopa on akinesia and gait.
Identifieur interne : 000155 ( Main/Exploration ); précédent : 000154; suivant : 000156Subthalamic stimulation may inhibit the beneficial effects of levodopa on akinesia and gait.
Auteurs : Vanessa Fleury [Suisse] ; Pierre Pollak [Suisse] ; Julien Gere [France] ; Giorgio Tommasi [France] ; Luigi Romito [France] ; Christophe Combescure [Suisse] ; Eric Bardinet [France] ; Stephan Chabardes [France] ; Shahan Momjian [Suisse] ; Alexandre Krainik [France] ; Pierre Burkhard [Suisse] ; Jérôme Yelnik [France] ; Paul Krack [France]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2016.
Abstract
Gait and akinesia deterioration in PD patients during the immediate postoperative period of DBS has been directly related to stimulation in the subthalamic region. The underlying mechanisms remain poorly understood. The aim of the present study was to clinically and anatomically describe this side effect.
DOI: 10.1002/mds.26545
PubMed: 26887333
Affiliations:
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sort="Fleury, Vanessa" uniqKey="Fleury V" first="Vanessa" last="Fleury">Vanessa Fleury</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Geneva University Hospital, Geneva, Switzerland. Vanessa.FleuryNissen@hcuge.ch.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neurology, Geneva University Hospital, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Geneva University Hospital, Geneva, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neurology, Geneva University Hospital, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Gere, Julien" sort="Gere, Julien" uniqKey="Gere J" first="Julien" last="Gere">Julien Gere</name><affiliation wicri:level="3"><nlm:affiliation>Movement Disorder Unit, Department of Psychiatry and Neurology, Grenoble University Hospital, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Movement Disorder Unit, Department of Psychiatry and Neurology, Grenoble University Hospital, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Tommasi, Giorgio" sort="Tommasi, Giorgio" uniqKey="Tommasi G" first="Giorgio" last="Tommasi">Giorgio Tommasi</name><affiliation wicri:level="3"><nlm:affiliation>Movement Disorder Unit, Department of Psychiatry and Neurology, Grenoble University Hospital, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Movement Disorder Unit, Department of Psychiatry and Neurology, Grenoble University Hospital, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old 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region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Chabardes, Stephan" sort="Chabardes, Stephan" uniqKey="Chabardes S" first="Stephan" last="Chabardes">Stephan Chabardes</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurosurgery, Grenoble University Hospital, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurosurgery, Grenoble University Hospital, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Momjian, Shahan" sort="Momjian, Shahan" uniqKey="Momjian S" first="Shahan" last="Momjian">Shahan Momjian</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurosurgery, Geneva University Hospital, Geneva, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neurosurgery, Geneva University Hospital, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Krainik, Alexandre" sort="Krainik, Alexandre" uniqKey="Krainik A" first="Alexandre" last="Krainik">Alexandre Krainik</name><affiliation wicri:level="3"><nlm:affiliation>US 017, INSERM, UMS 3552, CNRS, Grenoble University Hospital, Neuroradiology and MRI, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>US 017, INSERM, UMS 3552, CNRS, Grenoble University Hospital, Neuroradiology and MRI, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Burkhard, Pierre" sort="Burkhard, Pierre" uniqKey="Burkhard P" first="Pierre" last="Burkhard">Pierre Burkhard</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Geneva University Hospital, Geneva, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neurology, Geneva University Hospital, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Yelnik, Jerome" sort="Yelnik, Jerome" uniqKey="Yelnik J" first="Jérôme" last="Yelnik">Jérôme Yelnik</name><affiliation wicri:level="3"><nlm:affiliation>Sorbonne Université, UPMC Univ Paris, Inserm U975, CNRS UMR 7225, Centre de Neuroimagerie de Recherche, Institut du Cerveau et de la Moelle Épinière, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sorbonne Université, UPMC Univ Paris, Inserm U975, CNRS UMR 7225, Centre de Neuroimagerie de Recherche, Institut du Cerveau et de la Moelle Épinière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name><affiliation wicri:level="3"><nlm:affiliation>Movement Disorder Unit, Department of Psychiatry and Neurology, Grenoble University Hospital, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Movement Disorder Unit, Department of Psychiatry and Neurology, Grenoble University Hospital, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Gait and akinesia deterioration in PD patients during the immediate postoperative period of DBS has been directly related to stimulation in the subthalamic region. The underlying mechanisms remain poorly understood. The aim of the present study was to clinically and anatomically describe this side effect.</div></front></TEI><affiliations><list><country><li>France</li><li>Suisse</li></country><region><li>Auvergne-Rhône-Alpes</li><li>Rhône-Alpes</li><li>Île-de-France</li></region><settlement><li>Grenoble</li><li>Paris</li></settlement></list><tree><country name="Suisse"><noRegion><name sortKey="Fleury, Vanessa" sort="Fleury, Vanessa" uniqKey="Fleury V" first="Vanessa" last="Fleury">Vanessa Fleury</name></noRegion><name sortKey="Burkhard, Pierre" sort="Burkhard, Pierre" uniqKey="Burkhard P" first="Pierre" last="Burkhard">Pierre Burkhard</name><name sortKey="Combescure, Christophe" sort="Combescure, Christophe" uniqKey="Combescure C" first="Christophe" last="Combescure">Christophe Combescure</name><name sortKey="Momjian, Shahan" sort="Momjian, Shahan" uniqKey="Momjian S" first="Shahan" last="Momjian">Shahan Momjian</name><name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name></country><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Gere, Julien" sort="Gere, Julien" uniqKey="Gere J" first="Julien" last="Gere">Julien Gere</name></region><name sortKey="Bardinet, Eric" sort="Bardinet, Eric" uniqKey="Bardinet E" first="Eric" last="Bardinet">Eric Bardinet</name><name sortKey="Chabardes, Stephan" sort="Chabardes, Stephan" uniqKey="Chabardes S" first="Stephan" last="Chabardes">Stephan Chabardes</name><name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name><name sortKey="Krainik, Alexandre" sort="Krainik, Alexandre" uniqKey="Krainik A" first="Alexandre" last="Krainik">Alexandre Krainik</name><name sortKey="Romito, Luigi" sort="Romito, Luigi" uniqKey="Romito L" first="Luigi" last="Romito">Luigi Romito</name><name sortKey="Tommasi, Giorgio" sort="Tommasi, Giorgio" uniqKey="Tommasi G" first="Giorgio" last="Tommasi">Giorgio Tommasi</name><name sortKey="Yelnik, Jerome" sort="Yelnik, Jerome" uniqKey="Yelnik J" first="Jérôme" last="Yelnik">Jérôme Yelnik</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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